KEGG   Bubalus bubalis (water buffalo): 102412431
Entry
102412431         CDS       T05912                                 
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
  KO
K09490  endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub03060  Protein export
bbub04141  Protein processing in endoplasmic reticulum
bbub04612  Antigen processing and presentation
bbub04918  Thyroid hormone synthesis
bbub05012  Parkinson disease
bbub05014  Amyotrophic lateral sclerosis
bbub05020  Prion disease
bbub05022  Pathways of neurodegeneration - multiple diseases
bbub05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03060 Protein export
    102412431 (HSPA5)
   04141 Protein processing in endoplasmic reticulum
    102412431 (HSPA5)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    102412431 (HSPA5)
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    102412431 (HSPA5)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    102412431 (HSPA5)
   05014 Amyotrophic lateral sclerosis
    102412431 (HSPA5)
   05020 Prion disease
    102412431 (HSPA5)
   05022 Pathways of neurodegeneration - multiple diseases
    102412431 (HSPA5)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102412431 (HSPA5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:bbub03110]
    102412431 (HSPA5)
   04131 Membrane trafficking [BR:bbub04131]
    102412431 (HSPA5)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:bbub04147]
    102412431 (HSPA5)
Enzymes [BR:bbub01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.10  non-chaperonin molecular chaperone ATPase
     102412431 (HSPA5)
Chaperones and folding catalysts [BR:bbub03110]
 Heat shock proteins
  HSP70 / DNAK
   102412431 (HSPA5)
Membrane trafficking [BR:bbub04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   ER-Golgi intermediate compartment (ERGIC) proteins
    102412431 (HSPA5)
Exosome [BR:bbub04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   102412431 (HSPA5)
  Exosomal proteins of other body fluids (saliva and urine)
   102412431 (HSPA5)
  Exosomal proteins of colorectal cancer cells
   102412431 (HSPA5)
SSDB
Motif
Pfam: HSP70 MreB_Mbl Hydantoinase_A FtsA DDR FGGY_C ParM_N Tombus_movement
Other DBs
NCBI-GeneID: 102412431
NCBI-ProteinID: XP_006049327
EnsemblRapid: ENSBBUG00015004805
LinkDB
Position
12:complement(95580693..95585065)
AA seq 655 aa
MKLSLVAAVLLLLLGTARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGN
RITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKV
VEKKTKPYIQVDVGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDA
QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDN
GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL
SSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI
VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDV
CPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLL
GTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIE
RMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE
EKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTSEEEAADKDEL
NT seq 1968 nt   +upstreamnt  +downstreamnt
atgaagctgtccctggtggctgcggtgctgctgctgctgctcggcacggcacgcgcggag
gaggaggacaagaaggaggacgtgggcacggtggtcggcatcgacctgggtaccacctac
tcctgcgttggggtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaac
cgcatcacgccgtcttatgtggctttcactcctgaaggggagcgtctgatcggcgatgca
gccaagaaccagctcacctccaatccggagaacacagtcttcgacgccaagcgactcatt
ggccggacgtggaatgacccgtccgtgcagcaggacatcaagttcttgcctttcaaggtg
gttgaaaagaaaactaaaccatacattcaagttgatgttggaggtgggcaaacaaagaca
tttgctcctgaagaaatttctgccatggttctcactaaaatgaaggaaactgctgaggct
tatttgggaaagaaggttactcatgcagttgttactgtaccagcatatttcaatgatgcc
caacgccaggcaaccaaagatgctggaactattgctggattgaatgtcatgaggatcatc
aatgagcctacagcagctgctattgcttatggcctggataagagggaaggggagaagaac
atcctggtgtttgacctgggtggtggaacctttgatgtgtctcttctcaccattgataat
ggtgtctttgaagtcgtggccactaatggagatactcatctgggtggagaagactttgac
cagcgtgtcatggaacacttcatcaaactctacaaaaagaagactggcaaagatgttcgg
aaggacaacagagctgtgcagaaactccggcgtgaggtagaaaaggccaaacgggccctg
tcttcccaacatcaagcaagaattgaaatcgagtccttctatgaaggagaagacttctcg
gagaccctgactcgggctaaatttgaagagctaaacatggacctgttccgttccaccatg
aagcctgtccagaaagtgttggaagattctgatttaaagaagtctgatattgatgaaatt
gttcttgttggtggctctactcgaatcccaaagattcaacagctggttaaagagtttttc
aatggcaaggagccatcccgtggcataaacccagatgaggctgtggcatatggtgccgct
gtccaggctggtgtgctctctggtgatcaagatacaggtgacctggtactgcttgatgta
tgtcccctgacacttggtattgaaactgtgggaggtgtcatgaccaaactgattccaagg
aacactgtggtgcccaccaagaagtctcagatcttttctacagcctctgataatcaacca
actgttaccatcaaggtctatgaaggtgaacgacccctgacgaaagacaatcaccttctg
ggaactttcgacctgactggaattcctcctgcaccccgtggggtcccacagattgaagtc
acctttgagatagatgtgaatggcattcttcgagtgacagctgaagacaaaggtacaggc
aacaaaaataagatcacaattaccaatgatcaaaatcgcctgacacctgaagaaattgaa
agaatggtcaatgatgctgagaagtttgctgaggaagacaaaaagctcaaggagcgcatc
gacacaagaaatgaattggaaagctatgcctactctcttaagaatcagattggagataaa
gaaaaactgggaggtaaactttcctcagaagataaggagaccatggaaaaagctgtagaa
gaaaagattgagtggctggaaagtcaccaagatgctgacattgaagatttcaaagctaaa
aagaaggagctagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggc
ccgcccccaaccagtgaggaggaagcagcagacaaagatgagttgtag

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