KEGG   Bubalus bubalis (water buffalo): 102414534
Entry
102414534         CDS       T05912                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X7
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub04010  MAPK signaling pathway
bbub04020  Calcium signaling pathway
bbub04022  cGMP-PKG signaling pathway
bbub04114  Oocyte meiosis
bbub04218  Cellular senescence
bbub04310  Wnt signaling pathway
bbub04360  Axon guidance
bbub04370  VEGF signaling pathway
bbub04380  Osteoclast differentiation
bbub04625  C-type lectin receptor signaling pathway
bbub04650  Natural killer cell mediated cytotoxicity
bbub04658  Th1 and Th2 cell differentiation
bbub04659  Th17 cell differentiation
bbub04660  T cell receptor signaling pathway
bbub04662  B cell receptor signaling pathway
bbub04720  Long-term potentiation
bbub04724  Glutamatergic synapse
bbub04728  Dopaminergic synapse
bbub04921  Oxytocin signaling pathway
bbub04922  Glucagon signaling pathway
bbub04924  Renin secretion
bbub05010  Alzheimer disease
bbub05014  Amyotrophic lateral sclerosis
bbub05020  Prion disease
bbub05022  Pathways of neurodegeneration - multiple diseases
bbub05031  Amphetamine addiction
bbub05152  Tuberculosis
bbub05163  Human cytomegalovirus infection
bbub05166  Human T-cell leukemia virus 1 infection
bbub05167  Kaposi sarcoma-associated herpesvirus infection
bbub05170  Human immunodeficiency virus 1 infection
bbub05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bbub05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102414534 (PPP3CB)
   04310 Wnt signaling pathway
    102414534 (PPP3CB)
   04370 VEGF signaling pathway
    102414534 (PPP3CB)
   04020 Calcium signaling pathway
    102414534 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    102414534 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102414534 (PPP3CB)
   04218 Cellular senescence
    102414534 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    102414534 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    102414534 (PPP3CB)
   04660 T cell receptor signaling pathway
    102414534 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    102414534 (PPP3CB)
   04659 Th17 cell differentiation
    102414534 (PPP3CB)
   04662 B cell receptor signaling pathway
    102414534 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    102414534 (PPP3CB)
   04921 Oxytocin signaling pathway
    102414534 (PPP3CB)
   04924 Renin secretion
    102414534 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    102414534 (PPP3CB)
   04728 Dopaminergic synapse
    102414534 (PPP3CB)
   04720 Long-term potentiation
    102414534 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    102414534 (PPP3CB)
   04380 Osteoclast differentiation
    102414534 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102414534 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102414534 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    102414534 (PPP3CB)
   05163 Human cytomegalovirus infection
    102414534 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102414534 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    102414534 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102414534 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    102414534 (PPP3CB)
   05020 Prion disease
    102414534 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    102414534 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    102414534 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102414534 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:bbub01009]
    102414534 (PPP3CB)
Enzymes [BR:bbub01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     102414534 (PPP3CB)
Protein phosphatases and associated proteins [BR:bbub01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     102414534 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 102414534
NCBI-ProteinID: XP_025140540
EnsemblRapid: ENSBBUG00015000644
LinkDB
Position
4:complement(148587146..148630979)
AA seq 514 aa
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDMDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDGSAAARKEIIRNKIRAIGKMARVFS
VLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSAIRGFSPPHRICSFEEAKGLDRINE
RMPPRKDAVQQDGFNSLNTAHATENHGTGNHGAQ
NT seq 1545 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggctgcaccgcccccacccccgcccccgccgccccct
cccggggctgaccgcgtcgtcaaagctgttcctttccccccaacacatcgcttgacatct
gaagaagtatttgatatggatgggatacccagggttgatgttctgaagaaccacttagta
aaagaaggtcgggtagatgaagaaattgcacttagaattatcaatgagggtgctgccatt
cttcggagagagaaaaccatgatagaagtagaggctccaattacagtgtgtggtgacatc
catggccaattttttgatctgatgaaactttttgaagtaggaggatcacctgctaataca
cgatacctttttcttggtgattatgtggacagaggttattttagtatagagtgtgtctta
tatttatgggtcctgaagattctatatccaagtacattatttcttctgagaggcaaccat
gaatgcagacaccttactgaatattttacctttaagcaggaatgtaaaattaaatattca
gaaagagtctatgaagcttgtatggaagcttttgatagcttgcctcttgctgcactttta
aaccaacaatttctttgtgttcatggtggactttcaccagaaatacacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgcta
tggtccgatccttctgaagattttggaaatgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtgtgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacagtttaactgttctccacatccttattggttgcccaattttatggatgttttcaca
tggtctttaccgtttgttggagaaaaagtgacagaaatgttggtaaacgttctgagtatt
tgctctgatgatgaacttatgactgaaggcgaagaccagtttgatggttcagctgcagcc
cggaaagaaatcataagaaacaaaattcgagcaattggcaagatggcaagggtcttctct
gttctcagggaggagagtgaaagtgtgctgacactcaagggcctgactcccacagggatg
ttgcctagtggagtgttggctggaggacggcagaccctgcaaagtgcaatacgaggattc
tctccaccacatagaatctgcagttttgaagaggcaaagggtttggataggatcaatgag
agaatgccaccccggaaagatgctgtacagcaagatggtttcaattctctgaacaccgca
catgccactgagaaccacgggactggcaaccatggtgcccagtga

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