Bos indicus (zebu cattle): 109563399 Help Entry 109563399         CDS       T04792                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 isoform X1   KO K10160   toll-like receptor 4 Organism biu  Bos indicus (zebu cattle) Pathway biu04064   NF-kappa B signaling pathway biu04066   HIF-1 signaling pathway biu04145   Phagosome biu04151   PI3K-Akt signaling pathway biu04217   Necroptosis biu04613   Neutrophil extracellular trap formation biu04620   Toll-like receptor signaling pathway biu04621   NOD-like receptor signaling pathway biu04936   Alcoholic liver disease biu05132   Salmonella infection biu05133   Pertussis biu05134   Legionellosis biu05135   Yersinia infection biu05140   Leishmaniasis biu05142   Chagas disease biu05144   Malaria biu05145   Toxoplasmosis biu05146   Amoebiasis biu05152   Tuberculosis biu05161   Hepatitis B biu05162   Measles biu05164   Influenza A biu05170   Human immunodeficiency virus 1 infection biu05171   Coronavirus disease - COVID-19 biu05205   Proteoglycans in cancer biu05235   PD-L1 expression and PD-1 checkpoint pathway in cancer biu05321   Inflammatory bowel disease biu05323   Rheumatoid arthritis biu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:biu00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     109563399 (TLR4)    04066 HIF-1 signaling pathway     109563399 (TLR4)    04151 PI3K-Akt signaling pathway     109563399 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     109563399 (TLR4)   09143 Cell growth and death    04217 Necroptosis     109563399 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     109563399 (TLR4)    04620 Toll-like receptor signaling pathway     109563399 (TLR4)    04621 NOD-like receptor signaling pathway     109563399 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     109563399 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     109563399 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     109563399 (TLR4)    05161 Hepatitis B     109563399 (TLR4)    05171 Coronavirus disease - COVID-19     109563399 (TLR4)    05164 Influenza A     109563399 (TLR4)    05162 Measles     109563399 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     109563399 (TLR4)    05135 Yersinia infection     109563399 (TLR4)    05133 Pertussis     109563399 (TLR4)    05134 Legionellosis     109563399 (TLR4)    05152 Tuberculosis     109563399 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     109563399 (TLR4)    05144 Malaria     109563399 (TLR4)    05145 Toxoplasmosis     109563399 (TLR4)    05140 Leishmaniasis     109563399 (TLR4)    05142 Chagas disease     109563399 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     109563399 (TLR4)    05321 Inflammatory bowel disease     109563399 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     109563399 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     109563399 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:biu04131]     109563399 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:biu04054]     109563399 (TLR4)    04090 CD molecules [BR:biu04090]     109563399 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:biu00536]     109563399 (TLR4) Membrane trafficking [BR:biu04131]  Endocytosis   Phagocytosis    Toll-like receptors     109563399 (TLR4) Pattern recognition receptors [BR:biu04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    109563399 (TLR4) CD molecules [BR:biu04090]  Proteins   109563399 (TLR4) Glycosaminoglycan binding proteins [BR:biu00536]  Hyaluronan   Cell surface receptors    109563399 (TLR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 LRR_4 TIR LRR_1 TIR_2 LRR_9 LRR_6 ThsB_TIR Motif Other DBs NCBI-GeneID:  109563399 NCBI-ProteinID:  XP_019822383 UniProt:  A0A6P5CA83 LinkDB All DBs Position 8:112425284..112436302 Genome browser AA seq 841 aa AA seqDB search MMARARLAAXXIPATAILSCLRTESWDPCVQVVPNISYQCMELNLYKIPDNIPISTKMLD LSFNYLRHLGSHNFSSFPELQVLDLSRCEIKIIEDDTFQGLNHLSTLILTGNPIQSLAWG AFSGLSSLQKLVAVETNLVSLNDFPIGHLKXLKELNVAHNFIHSFKLPEYFSNLPNLEHL DLSNNKIQNIYYEDVKVLHQMPLLNLSLDLSLNPLDFIEPGTFKEIKLNGLTLRSNFNSS HVMKTCIQGLAGLKTNRLVLGEFKNERKLQRFDRSFLEGLCNLTIEQFRIAYLDKFSGDD TDLFNCLANVSVISLLSISLGSLQALLKDFRWQHLEIINCDFDKFPXLKLSSLKKFVFTD NKDISTFTEFQLPSLQYLDLKRNHLSFKGCCSHTDFGTTNLKHLDLSFNDVITLGSNFMG LEQLEHLDFQHSTLKQINAFSAFLSLRNLRYLDISYTNIRIVFHGIFTGLVSLQTLKMAG NSFQNNLLPDIFTELTNLTVLDLSKCQLEQVAQTAFHSLSSLQVLNMSHNKLLSLDTFLY EPLHSLRILDCSFNRIMASKEQELQNLPRSLTWLNLTQNAFACVCEHQSFLQWVKDQRQL LVGAEQMMCAEPLDMEDMPVLSFRNATCQLSKTIISVSVVTVLLVSVVGXLVYKFYFHLM LLAGCKKYGRGESTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIA ANIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKLEKSLL RQQVELYRLLSRNTYLEWEDSVLGRHVFWRRLRKALLAGKPQSPEGTADAETNPQEATTS T NT seq 2526 nt NT seq  +upstreamnt  +downstreamnt atgatggcgcgtgcccgcctggctgcgnnnnngatcccagccacggccatcctctcctgc ctgagaaccgagagytgggacccttgcgtacaggttgttcctaacattagttaccagtgc atggagctgaatctctacaaaatccccgacaacatccccatatcaaccaagatgctggac ctgagctttaactacctgagacatttaggcagccataacttctccagcttcccagaactg caagtgctggatttatccagatgtgaaattaagattattgaagacgacacatttcagggc ctaaaccacctctccaccttgatactgacgggaaaccctatccagagtttagcctgggga gccttttctgggctatcaagtttacagaagctggtggccgtggagacaaacctagtctct ctaaatgacttccccattggacatctcaaaamcttgaaagagcttaatgtggctcacaat tttatccattccttcaagttacctgaatatttttctaacctgcccaacctggagcacttg gatctttctaacaacaaaatccaaaatatttattatgaagatgtgaaagttctacatcaa atgcccctactcaacctctctttagatttgtccttgaaccctttagactttattgaacca ggtacctttaaagaaattaagctcaatggattgactctgcgaagtaattttaacagttca catgtcatgaaaacctgtattcaaggtctggctggtttaaaaaccaaccggctggttttg ggagaatttaaaaatgaaaggaagttgcaaagatttgacagatctttcctggagggactg tgcaacctgaccattgaacaattccggatagcgtacttggacaaattctcaggggacgat acagacttatttaattgtttggcaaatgtttctgtgatttctctgttgagtatatcttta ggaagtctacaagcccttcttaaagattttagatggcaacacttagaaattattaactgt gactttgacaagtttcctgmattgaagctcagttctctcaaaaagtttgttttcacagac aacaaagatataagcacttttactgagtttcagctaccgagccttcagtatctagatctc aaaagaaatcacttgagtttcaagggktgctgttctcacactgattttgggacaaccaac ctgaagcatttagatctgagcttcaatgatgtcattaccttaggttcaaacttcatgggc ttagagcaactagaacacctggattttcagcattccactctgaaacagatcaatgctttt tcagcattcctatcactcagaaacctccgctaccttgatatttcttataccaacatccgc attgtcttccatggcatctttactggcttagtcagtctgcaaaccttgaaaatggcaggc aactcttttcagaacaacttgctccctgacatcttcacagaactgactaacttaaccgtc ttggacctctctaagtgtcagctggaacaggtagcccagacagcatttcactccctctct agccttcaggtgctgaatatgagtcacaacaaactcttgtcactggatacatttctttat gaaccactccactcgctccggatcctagactgcagtttcaaccgtatcatggcctctaag gagcaagaactacagaatttgccaaggagcctcacttggctaaatcttactcagaatgca tttgcttgtgtttgtgaacatcagagyttcctgcagtgggtcaaggaccagaggcagctc ttggtgggagctgagcaaatgatgtgygcagagcctttagatatggaggacatgccagtg cttagtttcaggaaygccacttgtcagctgagcaagacgatcatcagtgtgtcggtggtc actgtgctcctggtgtctgtggtaggrrtcctagtctacaagttctatttccacctgatg cttcttgctggmtgcaaaaagtatggcaggggcgagagcacctatgaygcctttgtcatc tactcgagccaggatgaagactgggtgcggaatgaactggtaaagaacttggaggagggc gtgcccccctttcagctctgccttcactacagggactttattcctggggtggccatcgcc gccaatatcatccaggagggtttccacaaaagccgtaaggttattgtcgtggtgtcccag cacttcatccagagccgatggtgtatcttcgagtatgagattgcccagacctggcagttt ctgagcagccgtgctggcatcatcttcatcgtcctgcagaagctggagaagtctctcctg cggcagcaggtggagctctatcgccttctgagcaggaacacctacctggagtgggaggac agtgtcctggggcggcatgtcttctggagaagactcagaaaagccttgctggctggtaaa ccccagagtccagaaggaacagcagatgcagaaaccaacccgcaagaagcgacaacctcc acctga

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