Bos indicus (zebu cattle): 109564199 Help Entry 109564199         CDS       T04792                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04020   Calcium signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04727   GABAergic synapse biu04742   Taste transduction biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05032   Morphine addiction biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05207   Chemical carcinogenesis - receptor activation biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109564199 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109564199 (ADCY4)    04371 Apelin signaling pathway     109564199 (ADCY4)    04020 Calcium signaling pathway     109564199 (ADCY4)    04072 Phospholipase D signaling pathway     109564199 (ADCY4)    04024 cAMP signaling pathway     109564199 (ADCY4)    04022 cGMP-PKG signaling pathway     109564199 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109564199 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     109564199 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109564199 (ADCY4)    04062 Chemokine signaling pathway     109564199 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     109564199 (ADCY4)    04923 Regulation of lipolysis in adipocytes     109564199 (ADCY4)    04912 GnRH signaling pathway     109564199 (ADCY4)    04913 Ovarian steroidogenesis     109564199 (ADCY4)    04915 Estrogen signaling pathway     109564199 (ADCY4)    04914 Progesterone-mediated oocyte maturation     109564199 (ADCY4)    04921 Oxytocin signaling pathway     109564199 (ADCY4)    04926 Relaxin signaling pathway     109564199 (ADCY4)    04935 Growth hormone synthesis, secretion and action     109564199 (ADCY4)    04918 Thyroid hormone synthesis     109564199 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     109564199 (ADCY4)    04916 Melanogenesis     109564199 (ADCY4)    04925 Aldosterone synthesis and secretion     109564199 (ADCY4)    04927 Cortisol synthesis and secretion     109564199 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109564199 (ADCY4)    04270 Vascular smooth muscle contraction     109564199 (ADCY4)   09154 Digestive system    04970 Salivary secretion     109564199 (ADCY4)    04971 Gastric acid secretion     109564199 (ADCY4)    04972 Pancreatic secretion     109564199 (ADCY4)    04976 Bile secretion     109564199 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     109564199 (ADCY4)    04727 GABAergic synapse     109564199 (ADCY4)    04725 Cholinergic synapse     109564199 (ADCY4)    04723 Retrograde endocannabinoid signaling     109564199 (ADCY4)   09157 Sensory system    04742 Taste transduction     109564199 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     109564199 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     109564199 (ADCY4)    04213 Longevity regulating pathway - multiple species     109564199 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     109564199 (ADCY4)    04714 Thermogenesis     109564199 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109564199 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     109564199 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109564199 (ADCY4)    05163 Human cytomegalovirus infection     109564199 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     109564199 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109564199 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109564199 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109564199 (ADCY4) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109564199 (ADCY4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  109564199 NCBI-ProteinID:  XP_019823303 UniProt:  A0A6P5CCY5 LinkDB All DBs Position 10:21117001..21131622 Genome browser AA seq 1039 aa AA seqDB search MARLFSPRQPPSEDLFYETYYSLSQQYPLLLLLLLIVLLGLLALLPVAWASGRELAADPA FLTTVLCALGGFSLLLVLASREQRLQRWTRPLSGLVWAALLALGHSFLFTGGVVSAWDQV SFFLFVIFTVYAMLPLDMRDAITAGVTSSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL FLCGNAAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK EEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGCPHMAQAAEEDEKG TAGGLLSSLEGSKMRPSLLMTRYLESWGAAKPFAHLSHVESPVSTSTPLPEKALSSFSPQ WSLDRSRTMRGPDEELDTGDAKFFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRL SALPAFKYYAACTFLVFLSNFIIQMLVTNRPPALTITYGITFLLFFLLLFVCFSEHLMKC VLKGPKMLHWLPTLSVLVATRPGLRVALGTATILLVFVMAITSLVFLPATSACPFQAPNM SSMASNLSWELPGSLPLISIPYSMHCCVLGFLSCSLFLHMSFELKLLLLLLWLTASCSIF LHSHAWLSDCLIARLYLGTLDSRPGVLKEPKLMGAVSFFIFFFTLLVLARQNEYYCRLDF LWKKKLRQEQEETETMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFAS VPDFKEFYSESSINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTICSTYMAATGLN ATSGQDAQQDAEQSCGHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIG AQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETAWALQSLGYTCYSRGIIKVKGKGQLC TYFLNTDLTRTGPPSATLG NT seq 3120 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagtccacggcagccccccagcgaagacctcttctacgagacctac tacagcttgagccagcagtacccactgctgctgctgctgctgctgatcgtgctcttgggg ctcctggcgctgctccctgtggcctgggcaagtggcagggagctggccgcagacccagcc ttcctgaccactgtgctgtgcgctctgggtggcttctcactgctgctggtcctggcttcc cgggagcagcgactgcagcgctggacgcgtcccctgtcaggcctcgtgtgggcagcactg cttgcactaggccacagcttcctgttcactgggggcgtggtgagcgcctgggaccaggtg tcctttttcctttttgtcatcttcactgtgtatgccatgttgcccttggacatgcgggac gccatcaccgcgggtgtcacctcctcactctcacacttgctggtccttgggctgtatctt gggcctcagcccgactctcggccggcgctgctgccacagctggctgcaaacgcggtgctg ttcctgtgcgggaacgcggccggagcctatcacaaggcgctgatggagcgcgcgctgcgc gccacgttccgggaggcgcttagttccctgcactcgcggcggagactggacaccgagaag aagcatcaggaacaccttctcttgtccatccttcctgcctacctggcccgagagatgaag gaggagatcatggcacggctgcaggctggacaggggtcacggccagagagcaccaacaac tttcacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcacgagactggccagtgagtgctcccctaaggagttggtgcttatgctcaacgag ctctttggcaagttcgaccaaatcgccaaggagcacgaatgcatgcggatcaagatccta ggagactgttactactgtgtctccggcctgccgctctcactgcctgaccacgccatcaac tgtgtgcgcatggggctggacatgtgccgggccatcaggaaacttcgggcagccacaggc gtggatatcaacatgcgtgtgggcgtgcactcaggcagcgtgctctgcggggtcatcggg ctacagaaatggcagtatgatgtctggtcccatgacgtcactctggccaaccacatggag gcgagtggagtgccagggtgccctcatatggcccaggctgcagaggaggacgagaagggt actgcaggagggttgctgtcctctcttgagggctccaagatgcgtccatcactgctgatg acccgctacctggagtcctggggtgcagccaagcctttcgcccacctgagccacgtagag agccctgtgtccacatctacccctctcccggagaaggccctgtcttccttcagcccccag tggagcctggaccggagccgtaccatgaggggacctgatgaggaattagacactggggat gccaagttcttccaggtcatcgaacagctcaattctcagaaacaatggaaacagtcaaag gacttcaatccactgacactgtacttcagagagaaggagatggagaaagagtatcggctc tctgcactccccgccttcaaatactatgcagcctgcaccttcctggtttttctctccaac ttcattatccagatgctggtgacaaacaggcctccagctctgaccatcacctatggcatc accttcctcctcttcttcctcctcctcttcgtctgcttctcagagcacctgatgaagtgt gtcttgaaaggccccaagatgctgcactggctacccaccctgtctgtcctggtggccaca cggccaggactgcgagtggctctgggcaccgctaccatcctgctcgtcttcgtcatggcc attaccagtctggtcttcttaccagcaacatcagcctgcccttttcaggctcccaatatg tcctccatggcttccaacctctcctgggagctccctgggtccctgcctctcatcagcatc ccatactccatgcactgctgcgtgttgggcttcctctcctgctccctcttcctgcacatg agctttgagctgaagctgctgctgctcctgctgtggctgacggcctcctgctccatcttc ctgcactcccacgcctggttgtccgactgcctcatcgcccgcctctacctgggcaccttg gactccaggccaggggtgctgaaggagcccaaactgatgggagcagtctccttcttcatc ttcttcttcaccctcctagtcctggctcggcagaacgaatattactgccgcctggacttt ctgtggaagaagaagctgaggcaagagcaggaggagacagagacaatggagaacctgact cggctgctcttggagaacgtgctccctgcgcacgtggccccccagttcattggtcagaat cggcgcaatgaggacctctaccaccagtcctatgagtgtgtgtgtgtcctcttcgcctcg gtcccagacttcaaggagttctactctgaatccagcatcaaccatgaggggctagagtgt ctgcggctgctcaatgagataatcgctgattttgatgagctgctctccaagcccaagttc agtggggtggagaagatcaaaactatctgcagcacctacatggcagctaccggcttgaac gccacctctggacaggatgcacagcaggatgctgagcaaagctgcggccaccttggcacc atggtagagtttgctgtggcccttgggtctaagctggatgtcatcaacaagcactcattc aacaactttcgcttgcgtgtagggttaaaccacggacctgtagtggctggagtgattggg gcccagaaaccacaatatgacatctggggcaacacggtgaatgtggccagccgcatggag agcacaggtgtcctgggcaagattcaggtaacagaagagacagcctgggccctccagtcc ttaggctacacctgctacagccggggcatcatcaaggtcaaaggcaaagggcagctctgc acctacttcttgaacacagatttgacacgaactggacctccctcagccaccctaggctga

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