Bos indicus (zebu cattle): 109564346 Help Entry 109564346         CDS       T04792                                  Symbol SOS2 Name (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism biu  Bos indicus (zebu cattle) Pathway biu01521   EGFR tyrosine kinase inhibitor resistance biu01522   Endocrine resistance biu04010   MAPK signaling pathway biu04012   ErbB signaling pathway biu04014   Ras signaling pathway biu04062   Chemokine signaling pathway biu04068   FoxO signaling pathway biu04072   Phospholipase D signaling pathway biu04150   mTOR signaling pathway biu04151   PI3K-Akt signaling pathway biu04510   Focal adhesion biu04540   Gap junction biu04630   JAK-STAT signaling pathway biu04650   Natural killer cell mediated cytotoxicity biu04660   T cell receptor signaling pathway biu04662   B cell receptor signaling pathway biu04664   Fc epsilon RI signaling pathway biu04714   Thermogenesis biu04722   Neurotrophin signaling pathway biu04810   Regulation of actin cytoskeleton biu04910   Insulin signaling pathway biu04912   GnRH signaling pathway biu04915   Estrogen signaling pathway biu04917   Prolactin signaling pathway biu04926   Relaxin signaling pathway biu04935   Growth hormone synthesis, secretion and action biu05034   Alcoholism biu05160   Hepatitis C biu05161   Hepatitis B biu05163   Human cytomegalovirus infection biu05165   Human papillomavirus infection biu05200   Pathways in cancer biu05205   Proteoglycans in cancer biu05206   MicroRNAs in cancer biu05207   Chemical carcinogenesis - receptor activation biu05208   Chemical carcinogenesis - reactive oxygen species biu05210   Colorectal cancer biu05211   Renal cell carcinoma biu05213   Endometrial cancer biu05214   Glioma biu05215   Prostate cancer biu05220   Chronic myeloid leukemia biu05221   Acute myeloid leukemia biu05223   Non-small cell lung cancer biu05224   Breast cancer biu05225   Hepatocellular carcinoma biu05226   Gastric cancer biu05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:biu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     109564346 (SOS2)    04012 ErbB signaling pathway     109564346 (SOS2)    04014 Ras signaling pathway     109564346 (SOS2)    04630 JAK-STAT signaling pathway     109564346 (SOS2)    04068 FoxO signaling pathway     109564346 (SOS2)    04072 Phospholipase D signaling pathway     109564346 (SOS2)    04151 PI3K-Akt signaling pathway     109564346 (SOS2)    04150 mTOR signaling pathway     109564346 (SOS2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     109564346 (SOS2)    04540 Gap junction     109564346 (SOS2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     109564346 (SOS2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     109564346 (SOS2)    04660 T cell receptor signaling pathway     109564346 (SOS2)    04662 B cell receptor signaling pathway     109564346 (SOS2)    04664 Fc epsilon RI signaling pathway     109564346 (SOS2)    04062 Chemokine signaling pathway     109564346 (SOS2)   09152 Endocrine system    04910 Insulin signaling pathway     109564346 (SOS2)    04912 GnRH signaling pathway     109564346 (SOS2)    04915 Estrogen signaling pathway     109564346 (SOS2)    04917 Prolactin signaling pathway     109564346 (SOS2)    04926 Relaxin signaling pathway     109564346 (SOS2)    04935 Growth hormone synthesis, secretion and action     109564346 (SOS2)   09156 Nervous system    04722 Neurotrophin signaling pathway     109564346 (SOS2)   09159 Environmental adaptation    04714 Thermogenesis     109564346 (SOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109564346 (SOS2)    05206 MicroRNAs in cancer     109564346 (SOS2)    05205 Proteoglycans in cancer     109564346 (SOS2)    05207 Chemical carcinogenesis - receptor activation     109564346 (SOS2)    05208 Chemical carcinogenesis - reactive oxygen species     109564346 (SOS2)    05231 Choline metabolism in cancer     109564346 (SOS2)   09162 Cancer: specific types    05210 Colorectal cancer     109564346 (SOS2)    05225 Hepatocellular carcinoma     109564346 (SOS2)    05226 Gastric cancer     109564346 (SOS2)    05214 Glioma     109564346 (SOS2)    05221 Acute myeloid leukemia     109564346 (SOS2)    05220 Chronic myeloid leukemia     109564346 (SOS2)    05211 Renal cell carcinoma     109564346 (SOS2)    05215 Prostate cancer     109564346 (SOS2)    05213 Endometrial cancer     109564346 (SOS2)    05224 Breast cancer     109564346 (SOS2)    05223 Non-small cell lung cancer     109564346 (SOS2)   09172 Infectious disease: viral    05161 Hepatitis B     109564346 (SOS2)    05160 Hepatitis C     109564346 (SOS2)    05163 Human cytomegalovirus infection     109564346 (SOS2)    05165 Human papillomavirus infection     109564346 (SOS2)   09165 Substance dependence    05034 Alcoholism     109564346 (SOS2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     109564346 (SOS2)    01522 Endocrine resistance     109564346 (SOS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF PH Motif Other DBs NCBI-GeneID:  109564346 NCBI-ProteinID:  XP_019823385 UniProt:  A0A6P5CCJ3 LinkDB All DBs Position 10:complement(43126094..43241943) Genome browser AA seq 1348 aa AA seqDB search MAASPLVTEIYSLRTFVRXTDIVPNRILVHNFCLISIILLILKLRTFFFKVQEQVHPNLS ANEESLYYIEELIFQLLNKLCMAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKR RNPLLLPVDKIHPSLKEVLGYKVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQ QDIKVSMCADKVLMDMFDQDDIGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNM IIKVFREAFLSDRKLFKPSDIEKIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGS CFEDLAEEQAFDPYETLSQDILSPKFNENFSKLMARPAVALHFQSIADGFKEAVRYVLPR LMLVPVYHCWHYFELLKQLKIRSEEHEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPG DPVCPFYNRQLRSKHLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMXXXXXRGGTNLLFDG LMISCKPNHSQSRLPGCSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSIIY AAKSAEEKNNWMAALISLQYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENI VFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIE RFEIPEPEPTEADKLALEKGEQPISTDLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFER DLELLERLESFISSVRGKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHIS RPGQFETFDLMTLHPIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIR HTTNLTLWFEKCIVEAENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRL DHTFEALQERKRKILDDAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNND FLKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGCASEKEFT DYLFNKSLEIEPRNCKQPPRFPRKSAFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPC KISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLP HSKSFFSSCGSLHKLSEEPLIPPPLPPRKKFDQDASNSKGTMKSDDDPPAIPPRQPPPPK VKPRVPAPAGPFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFTLQPPPLGHLHR DPDWFRDVSTCPNSPNTPPSTPSPRVPRRCYVLSSSQNNLAHPQAPPVPPRQNSSPHLPK LPPKTYKRELSHPPVYRLPLLENAETPQ NT seq 4047 nt NT seq  +upstreamnt  +downstreamnt atggctgcctctcctcttgtcacagaaatttacagcctcaggacttttgtgagastgact gatatcgtccctaataggatccttgtacacaacttttgtttaataagtatcattttgctt atacttaaattgagaacttttttttttaaggttcaggagcaagtacatcccaatctctca gctaatgaagagtctctctattacattgaagagctgatttttcagctgcttaataaatta tgcatggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcct catccaattgataaatgggctattgctgatgcacagtctgccatagagaaacgaaaaaga agaaatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttaggg tacaaagtggactaccatgtatccctgtatattgtggctgtgctggagtatatctcagct gatattttgaaattggctggtaattatgtttttaatatccgacattatgaaatatctcaa caagacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggat gacataggcttggtttctctttgtgaagatgaacctagttcttcaggcgaattaaactac tatgaccttgttagaactgaaattgcagaagaaagacagtatctacgggaactaaatatg atcataaaagtgtttcgagaagcttttctttctgacagaaagctgtttaaaccttctgat attgaaaagattttcagtaacattttagatatacatgaattgactgtgaaacttttaggt ttaattgaagacacagttgaaatgactgatgaaagtagccctcatcccttagctggcagc tgttttgaagatctggcagaggagcaagcatttgatccttatgaaacattatcccaggat attctttcaccaaagtttaatgaaaattttagtaagttgatggccagacctgcagtggct ctacactttcagtccatcgctgatggttttaaagaggcagttcgttatgtccttccacgc cttatgctggtgccagtatatcattgttggcactattttgaattattaaagcaattgaaa atacgtagtgaagagcatgaagacagagaatgtttgaaccaagctattactgctctcatg aatctccaaggtagtatggaccgaatttacaagcagtattcacctagacgccgacctggg gatcctgtttgccctttttataatcgtcaattaagaagcaagcacctggctattaaaaaa atgaatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgt aatgaatttattatgnnnnnnnnnnnnngtcgaggcgggaccaatcttctctttgatggc ttaatgattagctgcaaacccaatcacagccagtcacgccttccaggatgcagtagtgca gaatacagattaaaagaaaaatttgtcatgaggaaaatacaaatatgtgataaagaagat acttgtgagtgcaaacatgcttttgaattagtatccaaagatgaaaacagcataatatat gctgctaagtctgccgaagagaaaaataattggatggcagcacttatttcccttcagtat cgtagtactcttgatcgaatgctagattcagtattattgaaggaagaaaatgaacaacca ttgagattaccaagtcctgaagtgtatcgttttgtggtaaaagactctgaggaaaacatt gtttttgaagacaacttgcagagtagaagtggaatccccattattaaaggaggaactgtg gtgaaattaattgaaaggctaacatatcatatgtacgcagatcccaattttgttcgtact tttcttactacatatcgttcattttgtaaaccacaggaattactaagcttactgattgaa cgatttgaaattccagagccagaacctactgaagcagataaattggcgttagaaaaaggc gagcagcccatcagtacagaccttaaaaggtttcgcaaggaatacgtccaaccagtacaa cttagggtcttaaatgtgtttcggcactgggttgaacaccatttttatgactttgaaaga gacttggagctgcttgaaagactagaatccttcatttcaagtgtaagagggaaagctatg aagaaatgggtagagtcaattgctaagatcatcaagaggaaaaaacaagctcaggcaaat ggtataagccataatattacctttgaaagtccacctccaccaattgaatggcatatcagc agaccaggacagtttgaaacatttgatctcatgacacttcatccaatagaaattgcacgt cagctgacccttttggaatctgatctctacaggaaagttcaaccttctgaacttgtaggg agtgtatggaccaaagaagataaagaaataaattctccaaatttattaaaaatgattcgc cacaccacaaatctcaccctctggtttgaaaaatgcattgtggaggcagaaaattttgag gaacgagtggcaatactgagtagaattatagaaattctgcaagtttttcaagatttgaat aatttcaatggtgtattggagatcgtcagtgcagtaaattcagtatcagtctatagacta gatcatacctttgaggcgttgcaggaaagaaaaaggaaaattttggatgacgctgtggaa ttaagtcaagatcattttaaaaaatatctagtgaaacttaagtcaatcaatccaccctgt gtgcctttttttggaatatatttaacaaatatactgaagactgaagaagggaataatgat tttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggaggaaagtagctgaa attactggagaaattcagcagtatcaaaatcaaccttactgtttacggatagaaccagaa atgaggagattctttgaaaaccttaaccccatgggatgtgcttctgaaaaagagtttaca gattatttgttcaacaagtcactagaaattgaaccccgaaattgcaaacagccacctcga tttcctaggaaatcagctttctccttaaaatctcctggaataaggcctaatacaggccga catggctctacctcaggtactttgcgaggtcacccaacaccattagaaagagaaccgtgt aaaataagctttagtcggattgctgaaacggagcttgaatcaacagtgtcagcaccaacc tctccaaatacaccatctaccccaccagtgtctgcttcttcagaccttagtgtgttttta gatgtggatctcaacagttcctgtggaagcaatagcatctttgctccagtcctcttgcct cattcaaagtctttcttcagttcgtgtggtagtttacataagctaagtgaagagccactg attcctcctccacttccacctcgaaaaaaatttgatcaggatgcttcaaattccaaggga actatgaaatctgatgatgacccccctgctattccaccaagacaacctcctcctccaaag gtaaaacccagagttcctgctcccgctggtccatttgacgggcctctgcacagtccacct ccaccrccgccgagagaccctcttcctgatacccctccaccggttccacttcggcctcca gaacactttataaactgtccgtttacccttcagccacctccactgggacatcttcacaga gatccagactggttcagagacgttagtacgtgtccaaattctccgaacactcctcctagc acaccctctccaagggtacctcgtcgatgctatgtgctcagttctagtcaaaataatctt gctcatcctcaagctccccctgttccaccaaggcagaattcaagccctcatctaccaaaa ctgccaccaaagacttacaaacgggagctttcacaccccccagtgtatagactgcctttg ttagaaaatgcagaaactcctcaatga

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