KEGG   Bifidobacterium animalis subsp. lactis AD011: BLA_0236
Entry
BLA_0236          CDS       T00819                                 
Symbol
ddlA
Name
(GenBank) D-alanine-D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
bla  Bifidobacterium animalis subsp. lactis AD011
Pathway
bla00470  D-Amino acid metabolism
bla00550  Peptidoglycan biosynthesis
bla01100  Metabolic pathways
bla01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:bla00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    BLA_0236 (ddlA)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    BLA_0236 (ddlA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    BLA_0236 (ddlA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:bla01011]
    BLA_0236 (ddlA)
Enzymes [BR:bla01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     BLA_0236 (ddlA)
Peptidoglycan biosynthesis and degradation proteins [BR:bla01011]
 Precursor biosynthesis
  Amino acid ligase
   BLA_0236 (ddlA)
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp CPSase_L_D2 ATP-grasp_4
Other DBs
NCBI-ProteinID: ACL28538
UniProt: B8DVN7
LinkDB
Position
298050..299186
AA seq 378 aa
MAKTRVAVLYGGKADEHSISCISAASFMRALDPELFEAVPIGITKTGTWFVDGQDPLGWN
LAEGLPEAVETPDSREVVLTIGDGGDGFHARNADGSLDSLGHIDVVLPALHGPFGEDGTI
QGLFEMMGVPYVGCGVLASAACMDKHYTKVLLRAAGIPVAPGITLDTRHYDASDEFATDG
EEFLRQVNEAGLQYPLFVKPSRAGSSFGVTKVEQIGDAAALAAAVFEASRHDWRVLVEQG
IDAREIECAVVRIHPTDPTRAALPGEVVLDRRSEGDDQFYDFDSKYMDSQASHTEIPAKI
GDDLIARVRETAVRAFDAVDGMGLSRVDTFVTADGDVLVNEINTLPGCTSISMFPQAWEA
MGIPFRTVVTDLIEGALA
NT seq 1137 nt   +upstreamnt  +downstreamnt
atggcgaagacacgggtggcggttctctacggcggcaaggcggacgaacattcgatttcc
tgcatctccgcagcctcattcatgcgcgcgctcgaccctgaactgttcgaggccgtgccg
atcggcatcacgaagaccggcacctggttcgtagacggccaggatccgctcggttggaat
ctggccgaaggactccccgaggcggttgagacgcccgattcgcgcgaagtggtgctcacc
attggcgacggtggcgacgggttccacgcccgcaatgctgacggctcgcttgattcgctc
ggtcacattgatgtggtgctgcccgcactgcacggcccgtttggcgaggatggcacgatc
caaggcctgttcgagatgatgggcgtgccgtacgtgggctgcggcgtgctcgcctcggcc
gcgtgcatggacaagcactacaccaaggtgctgttgcgcgccgccggcattccggtggcg
ccgggcatcacgctcgacacccgtcactacgacgcctccgacgagttcgccaccgacggc
gaggaattcctgcggcaggtgaacgaggccggtttgcagtacccgttgttcgtcaaaccc
agccgtgccggctccagcttcggtgtgaccaaggtggagcagattggcgacgcagccgca
ctcgccgccgctgtgttcgaggcgagccggcatgattggcgcgtgctggtcgagcagggc
attgacgcgcgcgaaatcgagtgcgctgtggtgcgcattcacccgaccgacccgacccgt
gccgcgctacctggcgaagtggtgctcgaccggcgcagcgaaggcgacgaccagttctac
gatttcgacagcaaatacatggactcccaggcgagccacaccgagattccggcgaagatt
ggcgatgacctgatcgcgcgcgtccgcgagaccgccgtacgcgcattcgacgcggtggac
ggcatgggactgagccgtgtggacaccttcgtgaccgcagatggcgatgtgcttgtcaat
gagatcaacacactgccaggttgcacttcgatttcgatgttcccgcaagcgtgggaggcc
atgggcattccgttccgcaccgtggtcaccgacctcatcgaaggcgcgctcgcctga

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