KEGG   Bos mutus (wild yak): 102277785
Entry
102277785         CDS       T02919                                 
Symbol
GCK
Name
(RefSeq) glucokinase
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
bom  Bos mutus (wild yak)
Pathway
bom00010  Glycolysis / Gluconeogenesis
bom00052  Galactose metabolism
bom00500  Starch and sucrose metabolism
bom00520  Amino sugar and nucleotide sugar metabolism
bom00524  Neomycin, kanamycin and gentamicin biosynthesis
bom01100  Metabolic pathways
bom01200  Carbon metabolism
bom01250  Biosynthesis of nucleotide sugars
bom04910  Insulin signaling pathway
bom04911  Insulin secretion
bom04917  Prolactin signaling pathway
bom04922  Glucagon signaling pathway
bom04930  Type II diabetes mellitus
bom04950  Maturity onset diabetes of the young
bom05230  Central carbon metabolism in cancer
Module
bom_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
bom_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
bom_M00892  UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:bom00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    102277785 (GCK)
   00052 Galactose metabolism
    102277785 (GCK)
   00500 Starch and sucrose metabolism
    102277785 (GCK)
   00520 Amino sugar and nucleotide sugar metabolism
    102277785 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    102277785 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    102277785 (GCK)
   04910 Insulin signaling pathway
    102277785 (GCK)
   04922 Glucagon signaling pathway
    102277785 (GCK)
   04917 Prolactin signaling pathway
    102277785 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    102277785 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102277785 (GCK)
   04950 Maturity onset diabetes of the young
    102277785 (GCK)
Enzymes [BR:bom01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     102277785 (GCK)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 102277785
NCBI-ProteinID: XP_005899472
LinkDB
Position
Un
AA seq 465 aa
MLDDRARMEISKKEKAEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHKEASVKMLPT
YVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTTHQMYSIPEDAMTGTAE
MLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNN
IVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMQN
VELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLYEKLIGGKYMGE
LVRLVLLKLVDENLLFHGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRPS
ATDCDIVRRACESVSTRAAHMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFK
ERFHAIVRRLTPSCEITFIESEEGSGRGAALISAVACKKACMLGQ
NT seq 1398 nt   +upstreamnt  +downstreamnt
atgctggatgacagagccaggatggagatctccaagaaggaaaaggcggaacagatcctg
gcagagttccagctgcaggaggaggacttgaagaaggtgatgaggcggatgcagaaggag
atggaccgaggcctgaggctggagacccacaaggaggccagtgtgaagatgctgcccacc
tatgtgcgctccaccccagagggctcagaagttggggacttcctctccctggacctgggt
ggcaccaacttccgggtgatgctggtgaaggtgggagaaggagaggcgggacagtggagt
gtgaagaccacgcaccagatgtactccatccccgaggatgccatgacgggtactgctgag
atgctctttgactacatctctgagtgcatctctgacttcctggataagcatcagatgaag
cataagaagctgcccttgggcttcaccttctcctttcccgtgaggcatgaagacattgac
aagggcatccttctcaactggaccaagggcttcaaggcctcgggagcagaaggcaacaac
attgtggggctcctgcgagatgccatcaagcggagaggtgactttgagatggacgtggtg
gccatggtgaatgacactgtggccacgatgatctcctgctactatgaagaccgccggtgt
gaggttggcatgattgtgggcacgggctgcaacgcttgctacatggaggagatgcagaac
gtggagctggtggaaggggacgagggccgcatgtgtgtcaacaccgagtggggcgccttc
ggggactcaggcgagctggacgagttcctgctggagtacgaccgcgtggtggatgagaac
tccctgaaccccggccagcagctgtacgagaaactcatcggtggcaagtacatgggcgag
ctggtgcggcttgtgctgctgaagcttgtggacgagaatctgctcttccacggagaggcc
tcggagcagctgcgcacgcgcggcgccttcgagacacgcttcgtgtctcaggtggagagc
gattccggtgaccgcaagcagatctacaatatcctgagcactctagggctgcgaccctcg
gccactgactgtgacatcgtgcgccgagcctgcgagagcgtgtccacgcgcgccgcgcac
atgtgcgccgcgggactggcgggagtcatcaaccggatgcgcgagagccgcagcgaggac
gtgatgcgcatcaccgtgggcgtggacggctcggtgtacaagctgcaccctagcttcaag
gagcggttccacgccatcgtgcgcaggctgacgcccagctgtgaaatcaccttcattgag
tcggaggagggcagcggccggggcgcggccttgatctccgcggtggcctgtaagaaggcc
tgcatgctgggccagtaa

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