Bos mutus (wild yak): 102286168 Help Entry 102286168         CDS       T02919                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism bom  Bos mutus (wild yak) Pathway bom00230   Purine metabolism bom01100   Metabolic pathways bom01522   Endocrine resistance bom04015   Rap1 signaling pathway bom04020   Calcium signaling pathway bom04022   cGMP-PKG signaling pathway bom04024   cAMP signaling pathway bom04062   Chemokine signaling pathway bom04072   Phospholipase D signaling pathway bom04114   Oocyte meiosis bom04211   Longevity regulating pathway bom04213   Longevity regulating pathway - multiple species bom04261   Adrenergic signaling in cardiomyocytes bom04270   Vascular smooth muscle contraction bom04371   Apelin signaling pathway bom04540   Gap junction bom04611   Platelet activation bom04713   Circadian entrainment bom04714   Thermogenesis bom04723   Retrograde endocannabinoid signaling bom04724   Glutamatergic synapse bom04725   Cholinergic synapse bom04727   GABAergic synapse bom04742   Taste transduction bom04750   Inflammatory mediator regulation of TRP channels bom04911   Insulin secretion bom04912   GnRH signaling pathway bom04913   Ovarian steroidogenesis bom04914   Progesterone-mediated oocyte maturation bom04915   Estrogen signaling pathway bom04916   Melanogenesis bom04918   Thyroid hormone synthesis bom04921   Oxytocin signaling pathway bom04923   Regulation of lipolysis in adipocytes bom04925   Aldosterone synthesis and secretion bom04926   Relaxin signaling pathway bom04927   Cortisol synthesis and secretion bom04928   Parathyroid hormone synthesis, secretion and action bom04934   Cushing syndrome bom04935   Growth hormone synthesis, secretion and action bom04970   Salivary secretion bom04971   Gastric acid secretion bom04972   Pancreatic secretion bom04976   Bile secretion bom05032   Morphine addiction bom05163   Human cytomegalovirus infection bom05166   Human T-cell leukemia virus 1 infection bom05200   Pathways in cancer bom05207   Chemical carcinogenesis - receptor activation bom05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bom00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102286168 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102286168 (ADCY4)    04371 Apelin signaling pathway     102286168 (ADCY4)    04020 Calcium signaling pathway     102286168 (ADCY4)    04072 Phospholipase D signaling pathway     102286168 (ADCY4)    04024 cAMP signaling pathway     102286168 (ADCY4)    04022 cGMP-PKG signaling pathway     102286168 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102286168 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     102286168 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102286168 (ADCY4)    04062 Chemokine signaling pathway     102286168 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     102286168 (ADCY4)    04923 Regulation of lipolysis in adipocytes     102286168 (ADCY4)    04912 GnRH signaling pathway     102286168 (ADCY4)    04913 Ovarian steroidogenesis     102286168 (ADCY4)    04915 Estrogen signaling pathway     102286168 (ADCY4)    04914 Progesterone-mediated oocyte maturation     102286168 (ADCY4)    04921 Oxytocin signaling pathway     102286168 (ADCY4)    04926 Relaxin signaling pathway     102286168 (ADCY4)    04935 Growth hormone synthesis, secretion and action     102286168 (ADCY4)    04918 Thyroid hormone synthesis     102286168 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     102286168 (ADCY4)    04916 Melanogenesis     102286168 (ADCY4)    04925 Aldosterone synthesis and secretion     102286168 (ADCY4)    04927 Cortisol synthesis and secretion     102286168 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102286168 (ADCY4)    04270 Vascular smooth muscle contraction     102286168 (ADCY4)   09154 Digestive system    04970 Salivary secretion     102286168 (ADCY4)    04971 Gastric acid secretion     102286168 (ADCY4)    04972 Pancreatic secretion     102286168 (ADCY4)    04976 Bile secretion     102286168 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     102286168 (ADCY4)    04727 GABAergic synapse     102286168 (ADCY4)    04725 Cholinergic synapse     102286168 (ADCY4)    04723 Retrograde endocannabinoid signaling     102286168 (ADCY4)   09157 Sensory system    04742 Taste transduction     102286168 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     102286168 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     102286168 (ADCY4)    04213 Longevity regulating pathway - multiple species     102286168 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     102286168 (ADCY4)    04714 Thermogenesis     102286168 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102286168 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     102286168 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102286168 (ADCY4)    05163 Human cytomegalovirus infection     102286168 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     102286168 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102286168 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102286168 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102286168 (ADCY4) Enzymes [BR:bom01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102286168 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  102286168 NCBI-ProteinID:  XP_005910346 UniProt:  L8HRR9 LinkDB All DBs Position Un AA seq 1077 aa AA seqDB search MARLFSPRQPPSEDLFYETYYSLSQQYPLLLLLLLIVLLGLLALLPVAWASGRELAADPA FLTTVLCALGGFSLLLVLASREQRLQRWTRPLSGLVWAALLALGHSFLFTGGVVSAWDQV SFFLFVIFTVYAMLPLDMRDAITAGVTSSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL FLCGNAAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK EEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGRVHITGATLALLAG AYAVEDAAMEHRDPYLRELGEPTYLVIDPWAAEEDEKGTAGGLLSSLEGSKMRPSLLMTR YLESWGAAKPFAHLSHVESPVSTSTPLPEKALSSFSPQWSLDRSRTMRGPDEELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFLSNFI IQMLVTNRPPALTITYGITFLLFFLLLFVCFSEYLMKCVLKGPKMLHWLPTLSVLVATRP GLRVALGTATILLVFVMAITSLVFLPATSACPFQAPNMSSMASNLSWELPGSLPLISIPY SMHCCVLGFLSCSLFLHMSFELKLLLLLLWLTASCSIFLHSHAWLSDCLIARLYLGTLDS RPGVLKEPKLMGAVSFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEQEETETMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESSINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTICSTYMAATGLNATSGQDAQQDAEQSCGHLGTMV EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETAWALQSLGYTCYSRGIIKVKGKGQLCTYFLNTDLTRTGPPSATLG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagtccacggcagccccccagcgaagacctcttctacgagacctac tacagcctgagccagcagtacccactgctgctgctgctgctgctgatcgtgctcttgggg ctcctggcgctgctccctgtggcctgggcaagtggcagggagctggccgcagacccagcc ttcctgaccactgtgctgtgcgctctgggtggcttctcactgctgctggtcctggcttcc cgggagcagcgactgcagcgctggacgcgtcccctgtcaggcctcgtgtgggcagcactg cttgcactaggccacagcttcctgttcactgggggcgtggtgagcgcctgggaccaggtg tcctttttcctctttgtcatcttcactgtgtatgccatgttgcccctggacatgcgggac gccatcaccgcgggtgtcacctcctcactctcacacttgctggtccttgggctgtatctt gggcctcagcccgactctcggccggcgctgctgccacagctggctgcaaacgcggtgctg ttcctgtgcgggaacgcggccggagcctatcacaaggcgctgatggagcgcgcgctgcgc gccacgttccgggaggcgcttagttccctgcactcgcggcggagactggacaccgagaag aagcatcaggaacaccttctcttgtccatccttcctgcctacctggcccgagagatgaag gaggagatcatggcacggctgcaggctggacaggggtcacggccagagagcaccaacaac ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcacgagactggccagtgagtgctcccctaaggagttggtgcttatgctcaacgag ctctttggcaagttcgaccaaatcgccaaggagcacgaatgcatgcggatcaagatccta ggagactgttactactgtgtctccggcctgccgctctcactgcctgaccacgccatcaac tgtgtgcgcatggggctggacatgtgccgggccatcaggaaacttcgggcagccacaggc gtggatatcaacatgcgtgtgggcgtgcactcaggcagcgtgctctgcggggtcatcggg ctacagaaatggcagtatgatgtctggtcccatgacgtcactctggccaaccacatggag gcgagtggagtgccaggacgagtacatatcacaggggctacgctggccctgctggccggg gcttatgctgtggaggatgcagccatggaacaccgggacccataccttcgggagctaggg gagccgacctacctggtcatcgacccctgggctgcagaggaggacgagaagggtactgca ggagggttgctgtcctctcttgagggctccaagatgcgtccatcactgctgatgacccgc tacctggagtcctggggtgcagccaagcctttcgcccacctgagccacgtggagagccct gtgtccacatctacccctctcccggagaaggccctgtcttccttcagcccccagtggagc ctggaccggagccgtaccatgaggggacctgatgaggaactagacactggggatgccaag ttcttccaggtcatcgaacagctcaattctcagaaacaatggaaacagtcgaaggacttc aatccactgacactgtacttcagagagaaggagatggagaaagagtatcggctctctgca ctccccgccttcaaatactatgcagcctgcaccttcctggtttttctctccaacttcatt atccagatgctggtgacaaacaggcctccagctctgaccatcacctatggcatcaccttc ctcctcttcttcctcctcctcttcgtctgcttctcagagtacctgatgaagtgtgtcttg aaaggccccaagatgctgcactggctacccaccctgtctgtcctggtggccacacggcca ggactgcgagtggctctgggcaccgctaccatcctgctcgtcttcgtcatggccattacc agtctggtcttcttaccagcaacatcagcctgcccttttcaggctcccaatatgtcttcc atggcttccaacctctcctgggagctccctgggtccctgcctctcatcagcatcccatac tccatgcactgctgcgtgttgggcttcctctcctgctccctcttcctgcacatgagcttt gagctgaagctgctgctgctcctgctgtggctgacggcctcctgctccatcttcctgcac tcccacgcctggttgtccgactgcctcatcgcccgcctctacctgggcaccttggactcc aggccaggggtgctgaaggagcccaaactgatgggagcagtctccttcttcatcttcttc ttcaccctcctagtcctggctcggcagaatgaatattactgccgcctggactttctgtgg aagaagaagctgaggcaagagcaggaggagacagagacaatggagaacctgactcggctg ctcttggagaacgtgctccctgcgcacgtggccccccagttcattggtcagaatcggcgc aatgaggacctctaccaccagtcctatgagtgtgtgtgtgtcctcttcgcctcggtccca gacttcaaggagttctactctgaatccagcatcaaccatgaggggctagagtgtctgcgg ctgctcaatgagataatcgctgattttgatgagctgctctccaagcccaagttcagtggg gtggagaagatcaaaactatctgcagcacctacatggcagctaccggcttgaacgccacc tctggacaggatgcacagcaggatgctgagcaaagctgcggccaccttggcaccatggta gagtttgctgtggcccttgggtctaagctggatgtcatcaacaagcactcattcaacaac tttcgcttgcgtgtagggttaaaccacggacctgtagtggctggagtgattggggcccag aaaccacaatatgacatctggggcaacacggtgaatgtggccagccgcatggagagcaca ggtgtcctgggcaagattcaggtaacagaagagacagcctgggccctccagtccttaggc tacacctgctacagccggggcatcatcaaggtcaaaggcaaagggcagctctgcacctac ttcttgaacacagatttgacacgaactggacctccctcagccaccctaggctga

DBGET integrated database retrieval system