KEGG   Mycetohabitans rhizoxinica: RBRH_03254
Entry
RBRH_03254        CDS       T01355                                 
Name
(GenBank) D-alanine--D-alanine ligase (EC 6.3.2.4)
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
brh  Mycetohabitans rhizoxinica
Pathway
brh00470  D-Amino acid metabolism
brh00550  Peptidoglycan biosynthesis
brh01100  Metabolic pathways
brh01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:brh00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    RBRH_03254
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    RBRH_03254
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    RBRH_03254
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:brh01011]
    RBRH_03254
Enzymes [BR:brh01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     RBRH_03254
Peptidoglycan biosynthesis and degradation proteins [BR:brh01011]
 Precursor biosynthesis
  Amino acid ligase
   RBRH_03254
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 TTL ATPgrasp_ST RimK ATP-grasp ATPgrasp_YheCD
Other DBs
NCBI-ProteinID: CBW73841
UniProt: E5ALG8
LinkDB
Position
302353..303300
AA seq 315 aa
MKMRAIDPKAFGKVAVLYGGESSERDVSLVSGRLACQGLRDAGVDAYLFDPKERPLSALK
DEGFARAFIALHGGYGENGQIQGALDFYGIRYTGPGVLGSALGMDKFRTKLIWQQLGIPT
PPFDTVLRGEDYDMRAQQIVAKLGLPLFVKPATEGSSVAVFKVKAADNLPHALAQAARHD
PVVLVEKSIDGGGEYTACIAGSLPLPLIRIVPAGEFYDYHAKYVADDTQYLIPCGLSDAD
EQRLTALARRAFEVLACTAWGRADFMLDSDGNPYFLEVNTSPGMTDHSLPPKAARAVGIS
YSELLVNVLALTLKD
NT seq 948 nt   +upstreamnt  +downstreamnt
atgaagatgcgcgcgattgatccaaaggcattcggtaaagtggcggtgctctatggcggt
gagtcgtccgagcgcgacgtgtcgctcgtgtccggtcggctggcgtgccagggactgcgc
gacgccggcgtggacgcgtacttgttcgatccgaaggagcggcccttgtcggcgcttaag
gacgaagggttcgcgcgcgcgttcattgcgttgcacggcggatatggcgaaaacggccag
atccagggcgcactcgacttctacgggatccgctacaccggcccgggcgtgctcggctcg
gcactgggcatggacaagttccgcacaaaactgatttggcagcagctcgggatcccgacg
ccgccgttcgacacggtactgcgtggcgaggactacgacatgcgggcgcagcagatcgtg
gcgaaactcgggttgccgctgttcgtcaagccggcgaccgaaggctcaagcgtcgcggtg
ttcaaggtcaaggcggccgacaatttgccgcatgcactggcgcaggccgcgcggcatgat
ccggtcgtgctggtggagaagagcatcgacggtgggggagaatacaccgcgtgcatcgcc
ggctcgttgccgttgccgctgatccggatcgtgccggctggtgagttctacgattaccat
gcgaaatacgtcgctgacgatacccagtacctgattccgtgcggcttgagcgatgccgac
gagcagcgactaacggcgctcgcgcgccgcgcgttcgaggtcctcgcatgcaccgcctgg
ggacgtgctgacttcatgctcgacagcgatggcaacccctatttcctggaggtcaacacc
tcgcccggtatgaccgatcactcattgccaccgaaggcggcgcgtgcggtcggcatctcg
tatagcgaactgctcgtgaacgtgcttgcgctcacgctgaaggattga

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