Bos taurus (cow): 512723
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Entry
512723 CDS
T01008
Symbol
DLAT
Name
(RefSeq) dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
KO
K00627
pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:
2.3.1.12
]
Organism
bta
Bos taurus (cow)
Pathway
bta00010
Glycolysis / Gluconeogenesis
bta00020
Citrate cycle (TCA cycle)
bta00620
Pyruvate metabolism
bta00785
Lipoic acid metabolism
bta01100
Metabolic pathways
bta01200
Carbon metabolism
bta01210
2-Oxocarboxylic acid metabolism
Module
bta_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
512723 (DLAT)
00020 Citrate cycle (TCA cycle)
512723 (DLAT)
00620 Pyruvate metabolism
512723 (DLAT)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
512723 (DLAT)
Enzymes [BR:
bta01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.12 dihydrolipoyllysine-residue acetyltransferase
512723 (DLAT)
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Motif
Pfam:
2-oxoacid_dh
Biotin_lipoyl
E3_binding
Motif
Other DBs
NCBI-GeneID:
512723
NCBI-ProteinID:
NP_001192659
Ensembl:
ENSBTAG00000010709
VGNC:
109392
UniProt:
P11180
Structure
PDB
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Position
15:22340056..22374925
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AA seq
647 aa
AA seq
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MWRVCARRAQNAAPRAGFGARWTAFREEPGAPCVTPQAGSALARCSSKTPGYGRVRALCG
WSPVSRATPRNRVLLQLWGSPSRRWYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKIN
EGELIAEVETDKATVGFESVEECYMAKILVAEGTRDVPVGAIICITVDKPEDVEAFKNYT
LDSSAAPAPPAAPAPTPAAPAPSPTPSAQAPGSSYPTHMQVLLPALSPTMTMGTVQRWEK
KVGEKLNEGDLLAEIETDKATIGFEVQEEGYLAKILIPEGTRDVPLGTPLCIIVEKEADI
PAFADYRPAEVTDLKPPAPPPIPSPAAPVPPAPQPVAPPPSAPRPAAPAGPKGRVFVSPL
AKKLAAEKGIDLTQVKGTGPDGRIIKKDIDSFVPTKAAPTPAAAVPPPSPGVAPVPTGVF
TDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKMLEGKSKISVNDFI
IKASALACLKVPEANSSWMDTVIRQNHVVDISVAVSTPAGLITPIVFNAHIKGLETIAND
VVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDRLVPA
DNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL
NT seq
1944 nt
NT seq
+upstream
nt +downstream
nt
atgtggcgcgtctgtgcgcgacgggctcagaatgcagccccccgggcgggattcggggct
cggtggacggcctttcgggaggagccgggagctccgtgcgtgaccccgcaggctggctcg
gctctggctcgctgcagcagcaagaccccagggtatggcagggtccgggcactctgcggc
tggagcccagtctctcgggccacaccgcggaatcgcgttttgctgcagctctggggatcg
cctagccgccgctggtatagcctacccccgcatcagaaggttccattgccttcactgtcc
cctacaatgcaggcaggcaccatagcccgctgggaaaagaaggaaggagaaaaaatcaat
gagggtgaactaattgcagaggttgaaaccgataaagctactgttggatttgagagtgtg
gaggagtgttacatggcaaagatccttgttgctgaaggtaccagagatgttccagttgga
gcaatcatctgtatcacagttgacaagcctgaagatgttgaagcctttaaaaattacaca
ctggattcttcagcagcacctgccccaccagcagccccggcaccaacccctgccgccccc
gctccatcacctacaccttctgctcaggctcctggtagctcatatcctactcacatgcag
gtgcttcttcctgccctgtctcccaccatgaccatgggcacagttcagagatgggaaaaa
aaagtgggtgagaagctaaatgaaggagatctattggcagagatagagactgacaaggcc
actataggttttgaggtacaggaagaaggttacctggcaaaaatcctgatccctgaaggc
acacgagatgtccctctaggaaccccgctctgtatcattgtggaaaaagaggcagatata
ccagcatttgctgactatcggccagctgaagtaactgatttaaaaccaccagcaccacca
cctatcccatctccggcagcccctgttcctccagctccccaacctgtagcccctccacct
tcagccccccggccagccgctccagctggaccaaagggaagggtgtttgttagcccgctt
gcgaagaagttggcagcagagaaagggattgaccttacacaagtaaaagggacaggacca
gatggcagaatcatcaagaaggacattgactcttttgtgcctactaaagctgctcctact
ccagcagccgccgtgcctcccccaagtccaggagtggctccagttcctacaggtgtcttc
acagatatcccaatcagcaacattcgccgagtcattgcacagcggttaatgcaatctaag
caaaccatacctcattattacctttctattgatgtaaatatgggagaagttttgttggta
cggaaagaacttaataagatgttagaaggaaaaagtaaaatttccgtcaatgacttcatt
ataaaagcttcagctttggcatgtttaaaagttcctgaagcaaattcttcttggatggac
acagttataagacaaaatcatgttgttgatatcagtgttgcagtcagtactcctgcagga
ctcatcacacctattgtatttaatgcacatataaaaggactggaaaccattgctaatgac
gttgtttctttagcaaccaaagcacgagagggtaaactacaaccacatgagttccagggt
ggcacttttacgatctcaaatttaggaatgtttgggattaagaacttctctgctattata
aacccacctcaagcatgtattttggcaattggtgcttcagaggatagactggttccagca
gataatgaaaaaggatttgatgtggccagcatgatgtctgttacactcagttgtgatcat
cgggttgtcgacggagcagttggagcccagtggcttgctgagtttagaaagtaccttgaa
aaacctatcaccatgttgttataa
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