Bos taurus (cow): 513730
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Entry
513730 CDS
T01008
Symbol
NOTCH2
Name
(RefSeq) neurogenic locus notch homolog protein 2 isoform X1
KO
K20994
Notch 2
Organism
bta
Bos taurus (cow)
Pathway
bta01522
Endocrine resistance
bta04330
Notch signaling pathway
bta04658
Th1 and Th2 cell differentiation
bta04919
Thyroid hormone signaling pathway
bta05165
Human papillomavirus infection
bta05200
Pathways in cancer
bta05206
MicroRNAs in cancer
bta05207
Chemical carcinogenesis - receptor activation
bta05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
513730 (NOTCH2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
513730 (NOTCH2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
513730 (NOTCH2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
513730 (NOTCH2)
05206 MicroRNAs in cancer
513730 (NOTCH2)
05207 Chemical carcinogenesis - receptor activation
513730 (NOTCH2)
09162 Cancer: specific types
05224 Breast cancer
513730 (NOTCH2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
513730 (NOTCH2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
513730 (NOTCH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
EGF
hEGF
EGF_CA
EGF_2
Ank_2
Ank
NOD
Notch
NODP
Ank_5
Ank_4
Ank_3
EGF_3
Motif
Other DBs
NCBI-GeneID:
513730
NCBI-ProteinID:
XP_002686160
BGD-bta:
BT29990
Ensembl:
ENSBTAG00000007909
LinkDB
All DBs
Position
3:23196522..23371805
Genome browser
AA seq
2471 aa
AA seq
DB search
MPALRPAPLWALLALWLCRAAPARALQCRDGYEPCVNEGICVTYHNGTGYCKCPEGFLGE
YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAPGFTGEDCQHSTTHPCFVSHPCLNGGT
CHVLSRDTYECTCQVGFTGKLCQWTDACLSHPCANGSTCTTMANQFSCTCLAGFTGQKCE
TDVNECDIPGQCQHGGTCLNLPGSYQCQCPQGFTGQHCDSPYVPCAPSPCVNGGTCRQTG
DFTFECSCLPGFEGVTCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
ECLLQPNACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGSDCTEDVDECA
MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCKNDATCLDKIGGFTC
LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
GAICSDQIDECYSSPCLNEGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCVHGVCM
DGVNRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRCICPEGPHHPSCYSQ
VNECLSNPCVHGNCTGGLTGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
CTCKKGFKGYNCQVNIDECASNPCLNQGTCLDDVSGYTCHCVLPYTGKNCQTVLAPCSPN
PCENAGVCKEAPNFESYSCLCAPGWQGQRCTIDIDECVSKPCMNHGLCHNTQGSYMCECP
PGFSGMDCEEDIDDCLANPCQNGGSCVDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN
GGTCSDYVNSYTCKCPAGFDGVHCENNIDECTESSCFNGGTCIDGINSFSCLCPVGFTGS
FCLHEINECNSHPCLNEGVCVDGLGTYRCICPLGYTGKNCQTLVNLCSRSPCKNKGTCIQ
DKAESRCLCPSGWAGAYCDVPSVSCEVAASHRGVPVDRLCQHSGVCISAGNSHHCQCPLG
YTGSYCEDQLDECSSNPCQHGATCRDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
TCIDLVNHFKCSCPPGTRGLLCEENVDDCARGPHCLNGGQCVDRIGGYSCRCLPGFAGER
CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSTFTGRHCETFVDVCPQMPCLNGGTCA
VASNMPDGFICRCPPGFSGARCQSSCGQVKCRRGEQCVHTASGPRCFCPNPQDCDSGCAS
SPCQHGGSCYPQRQPPYYSCQCAPPFRGSHCELYTAPTSTPPATCLSQYCADKARDGICD
DVCNSHACQWDGGDCSLTMEDPWANCSSPLPCWEYINNQCDELCNTAECLFDNFECQKSS
KTCKYDKYCADHYEDNHCDQGCNSEECGWDGLDCAADRPENLAEGTLVIVVLMPPEQLLQ
DARRFLRALGTLLHTNLRIKRSAQGELMVYPYYGGKSAAMKKQRLTRRSLPGDEEQEVAG
SQVFLEIDNRQCVQDSDQCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPKRTQLLY
LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDSSNHKRREPVGQDAVGLKNL
SVQVSEANLIGSGTSEHWVDDEGPQPKKAKAEDEALLSEEDDPIDRRPWTQQHLEAADIR
RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDMSDEDEDAEDSSANIIT
DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRPFLSLKHTPMG
KKSRRPNTKSTVPTSLPNLAKEAKDAKGNRRKKSLSDKGQLSESSVTLSPVDSLESPHTY
VSDTTSSPMITSPGILQASPNPMLATAAPTAPVHAQHALSFSNLHEMQPLAHGANTVLPS
VSQLLSHRHIVPPGSSTAGSLGRLHSVTVPADWMNRVEMNESQYNEMFGMVLAPAEGTHP
GIAPQSRPPEGKHLTTPREPLPPIVTFQLIPKGSIAQPTGAAQPPSNCPPAVAGTLPTMY
QIPEMARLPSMAFPTAMMPQQDGQVAQTILPAYHAFPASVGKYPTPPSQHSYASSNAAER
TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS
EPPRSNMQVYA
NT seq
7416 nt
NT seq
+upstream
nt +downstream
nt
atgcccgccctgcgccccgctccgctgtgggcgctgctggcactgtggctgtgccgcgcg
gccccggcgcgtgcattgcaatgtcgggatggctatgagccttgtgtaaatgaaggaata
tgtgttacctaccacaacggtacaggatactgcaagtgtccagagggcttcttgggagaa
tattgtcagcatcgagacccctgtgagaagaaccgttgccagaatggtgggacgtgtgtg
gcccaggctatgttggggaaagccacgtgccgctgtgccccgggcttcacgggcgaggac
tgccagcactcgactactcacccctgctttgtgtctcacccctgcctgaatgggggcacc
tgccacgtgcttagccgggacacctacgagtgtacctgccaagtcggttttacaggtaaa
ctgtgccagtggactgatgcctgcctgtcccacccctgtgcaaacggaagtacctgtacc
actatggccaaccagttctcctgcacatgccttgcaggcttcacagggcagaaatgtgag
actgatgtcaatgagtgtgacattccaggacagtgccagcacggtggcacctgcctcaac
ctcccaggctcctatcagtgccaatgcccccagggcttcacaggccagcactgcgacagt
ccctatgtgccctgcgcaccctccccctgtgtcaacggaggtacctgccggcagaccggt
gactttacctttgagtgcagttgccttccaggttttgaaggagtcacctgtgagcggaat
atagatgactgtcctaaccacaagtgtcagaatggaggggtttgtgtggatggggtcaat
acctacaactgccgctgtccccctcagtggacaggacagttctgcacagaggatgtggat
gagtgcctgctgcagcccaatgcctgtcagaacgggggcacctgtaccaaccgcaacggg
ggctatggctgtgtatgtgtgaatggctggagtggggacgactgcagtgagaatatcgat
gactgtgccttcgcctcctgcaccccgggctctacctgcatcgatcgtgtggcctccttc
tcttgtatgtgcccagaaggaaaggcaggtctcttatgtcatctggatgacgcgtgcatc
agcaacccctgccacaagggggcgctgtgtgataccaaccctctgaatggacagtatatt
tgcacctgcccacaaggctacaaagggagtgactgtacagaagatgtggatgagtgtgcc
atggccaacagcaatccttgtgagcatgcaggaaaatgtgtgaacacagatggtgccttc
cactgtgagtgtctgaagggctatgcaggacctcgttgtgagatggacatcaatgagtgc
cactcagacccctgcaagaatgatgccacctgtttggataagattggaggcttcacgtgt
ctgtgcatgccaggtttcaaaggtgtgcattgtgagttggagataaatgaatgtcagagc
aacccttgtgtgaacaatggacagtgtgtggataaagtcaatcgcttccagtgtctgtgt
ccgcctggattcacgggaccagtttgccagattgatattgatgactgttctagtactccg
tgtctgaatggggcaaagtgtatagatcacccgaatggctatgagtgccagtgtgccaca
ggattcactggtgtgttgtgtgaggagaacattgacaactgtgaccctgatccttgccac
cacggccagtgtcaggatggcattgattcctacacctgcatttgcaatccgggctacatg
ggcgccatctgcagtgaccagatagacgaatgctacagcagcccttgcctgaatgagggt
cgctgcatcgacctggtgaatggttaccagtgcaactgccagccaggcacgtcaggtgtt
aattgtgaaatcaattttgatgactgtgcaagtaacccgtgtgtccatggagtctgtatg
gatggcgttaatcgttacagctgtgtctgctcaccaggattcacagggcagagatgtaac
attgacattgatgagtgtgcctccaatccctgtcgcaagggtgcaacgtgcatcaatgat
gtgaatggtttccgctgtatctgccctgagggcccccaccatcccagctgctactcacag
gtgaacgagtgcctgagcaatccctgtgtccatggaaactgtactgggggcctcactgga
tacaagtgcctctgtgatgcaggctgggttggcatcaactgtgaagtggacaaaaatgaa
tgtctttctaatccatgccagaacgggggaacttgtgacaatctggtgaatggatacagg
tgcacttgcaagaagggctttaaaggctataactgccaggtgaatattgatgaatgtgct
tcaaatccatgtctgaaccaaggaacctgccttgatgacgtaagcggttatacttgccac
tgtgtgctgccatacacaggcaagaactgtcagaccgtattggctccctgttccccaaac
ccttgtgagaatgctggtgtttgcaaagaggcaccaaattttgagagttactcctgcctg
tgtgctcctggctggcaaggtcagcggtgtaccatcgacattgatgagtgtgtctccaag
ccctgcatgaaccacggtctctgccataacacccagggcagctacatgtgtgaatgtcct
ccaggcttcagtggcatggactgtgaggaggacattgatgactgccttgccaatccttgc
cagaatggaggttcctgtgtagatggagtgaatactttctcctgcctgtgccttccgggc
ttcactggggataaatgtcagacagacatgaatgagtgtctgagtgagccctgtaagaac
ggaggaacctgctctgactatgtcaacagttacacctgcaagtgcccggcgggatttgat
ggagtccactgtgagaacaacattgacgagtgcactgagagctcctgtttcaatggtggc
acgtgtatcgatgggattaactccttctcttgcttgtgccctgtgggcttcactggttcc
ttctgcctccatgagatcaatgaatgcaactctcatccatgcctgaatgaaggagtatgt
gttgatggcctgggtacctaccgctgtatctgcccattgggctacactggaaaaaactgt
cagaccctggtgaacctctgtagtcggtctccatgtaaaaacaaaggtacctgcattcag
gataaagcagagtcgcggtgcctgtgtccgtctggatgggctggtgcttactgcgatgtt
cccagtgtctcctgtgaggtggcggcctcccacagaggggtgcccgttgaccgcttgtgc
cagcactcaggcgtctgtatcagtgcgggcaactcgcatcactgccagtgccccctgggc
tacaccgggagctactgtgaggaccagcttgatgagtgctcgtccaatccctgccagcac
ggcgccacctgccgggacttcattggtggatacagatgtgagtgtgtccctggatatcag
ggtgtcaactgcgagtatgaagtggatgagtgccagaaccagccatgccagaatgggggc
acctgtatcgaccttgtgaaccacttcaagtgctcctgcccaccaggcactcggggcctg
ctttgtgaagagaacgttgacgactgtgccaggggtccccactgccttaatggtggccag
tgtgtagacaggattgggggctacagttgtcgctgcttgccaggctttgctggagaacgc
tgtgaaggggacatcaacgagtgcctgtccaacccctgcagctctgagggcagcctggac
tgcatacagctcaccaacgactacctgtgcgtctgccgcagcaccttcactggtcgtcac
tgtgaaacgttcgtcgacgtgtgtccccagatgccttgcctgaacggaggcacttgtgct
gtggccagcaacatgcccgatggtttcatctgtcgttgtcccccgggcttctctggggca
cgatgccagagcagctgcggacaggtgaagtgcaggagaggggagcaatgtgtgcacacg
gcctcgggcccccgctgcttctgccccaacccccaggactgcgactcgggctgcgccagt
agcccctgccagcacggggggagctgctaccctcagcgccagcctccttactactcgtgc
cagtgtgccccgccgttccggggcagccactgtgaactctacaccgcccccaccagcacc
cctcccgccacctgcctgagccagtattgtgctgacaaagctcgggacggcatctgtgat
gacgtgtgcaacagccatgcctgccagtgggatgggggggactgttccctcaccatggag
gacccctgggccaattgctcctccccgctgccctgctgggagtacatcaacaaccagtgc
gacgagctgtgcaacacggccgagtgcctgtttgacaactttgaatgccagaagagtagc
aagacatgcaaatatgacaaatactgtgcagaccactacgaagacaaccattgtgaccag
ggttgcaacagtgaggagtgtggctgggatgggctggactgtgctgctgaccggccagaa
aacctggcagagggcaccctggtcatcgtggtgctgatgccacctgaacagctgctccag
gatgcccgcagattcttgcgggcactgggcaccctgctccacaccaacctccgcatcaaa
cggtctgcccagggggaactcatggtctacccctattatggtgggaagtcagctgccatg
aagaagcagagactgacacgcaggtcccttcctggagatgaagaacaggaagtggctggc
tctcaggtatttctggagattgacaaccgccagtgtgttcaagactcagaccagtgcttt
aagaacacagacgcagccgcagctcttctggcttctcacgccatccaggggaccctgtcg
tacccacttgtgtctgtcgtcagtgaatctctgaccccaaaacgcactcagcttctctat
ctgcttgctgttgccgttgtcattatcttgtttattatcctgctgggggttatcatggca
aaacgaaagcgcaagcatggctccctctggctgcctgaaggtttcacccttcgccgtgac
tccagcaaccacaaacgtcgtgagccagtgggccaggatgctgtgggactcaaaaatctt
tcagtgcaagtctcagaggcgaacctaattggttctggaacaagtgaacactgggtcgat
gatgaagggccgcagcctaagaaagccaaggctgaagatgaggctttgctctcagaagaa
gatgaccccatcgatcggcgtccatggacacagcagcacctggaagctgcagacatccgt
aggacaccatcgctggctctcacccctccacaggcagagcaggaggtggacgtgctggat
gtgaacgtccgcggtccagatgggtgcaccccactgatgctggcttctctccgaggaggc
agctcagacatgagtgatgaagatgaagatgcagaggactcttctgccaacatcatcacg
gacctagtctaccagggtgccagcctccaagcacagacagaccggacgggtgagatggcc
ctgcatctcgcagcccggtactcaagggcagatgctgccaagcgtctcctggatgcaggt
gcagatgccaatgcccaggacaacatgggccgctgccctctccatgctgcagtggctgct
gatgcccaaggtgtcttccagatactgatccgcaaccgagtaactgatctagacgcaagg
atgaatgatggcactacacccctgatcctggctgcccgcctggcagtggagggaatggtg
gcagaactgatcaactgccaagcagatgtgaatgcagtggatgaccatggaaaatctgcc
cttcactgggcagctgctgtgaataatgtggaggcaacccttttgctgttgaaaaatggg
gccaaccgagacatgcaggacaacaaggaggagacacccctgtttcttgctgcccgggag
gggagctatgaagcagccaagatcctgttagaccattttgccaatcgggacatcacagac
cacatggatcgccttccccgggacgtggcccgggaccgcatgcaccatgacatcgtgcgc
ctgctggacgagtacaacgtgacccccagccctcccggcacagtgctgacttctgcgctc
tcacccgtcatctgtgggcccaacagaccttttctcagtttgaagcataccccaatgggc
aagaagtctagacggcctaacaccaagagtaccgtgcccactagcctccctaaccttgcc
aaggaggccaaggatgccaaggggaacaggaggaagaagtctctgagtgacaagggccag
ctgtccgagagctcagtgactctgtcccccgtcgattccctagaatctccgcacacatat
gtttctgacaccacctcctctccaatgatcacatcccccggaatcttacaggcctccccc
aaccccatgctggccactgccgcccccactgccccagtccatgcacagcatgcactgtct
ttctctaaccttcatgagatgcagcccttggctcatggggccaacactgtgcttccctcg
gtgagccagctgctgtctcaccgccacattgtgcccccgggcagcagcaccgcagggagc
ttgggtaggctgcattcagtcactgtccccgccgactggatgaaccgcgtggagatgaat
gagagccagtacaacgagatgttcggtatggtcctggctccagctgagggcacccaccct
ggcatagctccccagagcaggccgcccgaagggaagcatttaaccaccccacgagagccc
ttgccccccattgtgactttccagctaatccccaaaggcagcattgcccaaccaactggg
gctgcccagcctccgtccaactgccctccagctgttgcaggcaccctgcccaccatgtat
cagattccagaaatggctcgcttgcccagtatggcttttcccactgccatgatgccccag
caggatgggcaggttgctcagaccattctcccagcctatcacgccttcccagcctccgtg
ggcaagtatcccacacccccatcacagcatagctatgcttcctccaacgctgctgagaga
acgcccagtcacagtggtcacctccagggtgagcatccctacctgacaccgtccccagag
tctcctgaccagtggtcaagttcatcaccccactctgcttctgactggtcagatgtgacc
accagccccactcctgggggtgctggaggaggtcagcggggacctgggacacacatgtct
gagccaccacgcagcaacatgcaggtctatgcatga
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integrated database retrieval system
