Camelus dromedarius (Arabian camel): 105107124 Help Entry 105107124         CDS       T04642                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism cdk  Camelus dromedarius (Arabian camel) Pathway cdk01521   EGFR tyrosine kinase inhibitor resistance cdk04151   PI3K-Akt signaling pathway cdk04217   Necroptosis cdk04380   Osteoclast differentiation cdk04550   Signaling pathways regulating pluripotency of stem cells cdk04620   Toll-like receptor signaling pathway cdk04621   NOD-like receptor signaling pathway cdk04630   JAK-STAT signaling pathway cdk04658   Th1 and Th2 cell differentiation cdk04659   Th17 cell differentiation cdk05140   Leishmaniasis cdk05145   Toxoplasmosis cdk05152   Tuberculosis cdk05160   Hepatitis C cdk05161   Hepatitis B cdk05162   Measles cdk05163   Human cytomegalovirus infection cdk05164   Influenza A cdk05165   Human papillomavirus infection cdk05166   Human T-cell leukemia virus 1 infection cdk05167   Kaposi sarcoma-associated herpesvirus infection cdk05168   Herpes simplex virus 1 infection cdk05169   Epstein-Barr virus infection cdk05171   Coronavirus disease - COVID-19 cdk05200   Pathways in cancer cdk05203   Viral carcinogenesis cdk05212   Pancreatic cancer cdk05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:cdk00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     105107124 (JAK1)    04151 PI3K-Akt signaling pathway     105107124 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     105107124 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     105107124 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     105107124 (JAK1)    04621 NOD-like receptor signaling pathway     105107124 (JAK1)    04658 Th1 and Th2 cell differentiation     105107124 (JAK1)    04659 Th17 cell differentiation     105107124 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     105107124 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105107124 (JAK1)    05203 Viral carcinogenesis     105107124 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     105107124 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     105107124 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105107124 (JAK1)    05161 Hepatitis B     105107124 (JAK1)    05160 Hepatitis C     105107124 (JAK1)    05171 Coronavirus disease - COVID-19     105107124 (JAK1)    05164 Influenza A     105107124 (JAK1)    05162 Measles     105107124 (JAK1)    05168 Herpes simplex virus 1 infection     105107124 (JAK1)    05163 Human cytomegalovirus infection     105107124 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     105107124 (JAK1)    05169 Epstein-Barr virus infection     105107124 (JAK1)    05165 Human papillomavirus infection     105107124 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     105107124 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     105107124 (JAK1)    05140 Leishmaniasis     105107124 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105107124 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cdk01001]     105107124 (JAK1) Enzymes [BR:cdk01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105107124 (JAK1) Protein kinases [BR:cdk01001]  Non-receptor tyrosine kinases   JAK family [OT]    105107124 (JAK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  105107124 NCBI-ProteinID:  XP_031321163 LinkDB All DBs Position 13:complement(49881118..50092118) Genome browser AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPAPGVEVLFYLPDREPLRLGSGEYTAEEL CIRAAQECCISPLCHNLFALYDENTKLWYAPNHTITIDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMIKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN RFHPNDSGNVLYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNSFSYFPEITHIVIKESVVSVNKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSDRGFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT LMDYKDDEGTAEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPEEVYQLMRKCWEFQPSNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcaatatctaaacataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagaccgaggtgaatctggaggcccctgcgcccggggtggaggtgctcttc tatctcccggacagggagcccctccggctgggcagcggagagtacacggcggaggagctg tgcatcagggcggcgcaggagtgctgtatctctcctctgtgtcataacctctttgccctg tatgatgagaacaccaagctctggtatgctccaaatcacaccatcaccatcgacgacaag acgtcgctccggctccactaccggatgaggttctatttcaccaactggcatgggaccaat gataatgagcagtcagtatggcgacattccccaaagaagcagaagaatggctacgagaaa aaaaaagttccagatgcaacccctctccttgacgccagctcactggagtatctgtttgct cagggacagtacgatttggtcaagtgcctggctcccatccgagaccccaagacggagcag gacgggcatgatattgagaacgagtgtttgggaatggccgtcctggctatctcccactac gccatgataaagaagatgcagctgcccgagcttcccaaggatatcagctacaagcgatat attccagaaacactgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataacgttttcaaggatttcctaaaggagtttaacaacaagaccatctgcgacagcagc gtgtccacgcacgacctgaaggtgaagtacctggccaccttggagactctgacgaaacat tatggtgctgaaatatttgagacatccatgctactgatctcgtcagaaaatgagatgaat cggtttcatccgaatgacagtggaaacgttctctactatgaagtgatggtgactggaaat cttggaatccaatggaggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaa ctgaagcggaaaaaactggaaaataaacacaagaaggatgaggagaaaaacaaaatccgg gaagagtggaacagcttttcttacttccccgagatcactcacatcgtaatcaaggagtct gtggtcagcgttaataagcaggacaacaagaaaatggaactgaagctctcgtcccacgag gaggccttgtcttttgtgtccctggtggacggctacttccggctcacggcagatgcccac cattacctctgcaccgacgtggctcccccgctcattgtccacaacatacagaatggctgt catgggccaatctgcacagaatatgccatcaacaaattgcggcaagaaggaagcgaggag gggatgtacgtgctgcggtggagctgcaccgacttcgacaacatcctcatgaccgttacc tgcttcgaaaagtctgaggtgctgggtggccagaaacagttcaagaactttcagatcgag gtgcagaagggccgctacagcctgcacggctcagaccgcggcttccccagcctcggggac ctcatgagccacctgaagaagcagatcctgcgcacagacaacatcagcttcgtgctgaag cgctgctgccagcccaagccccgagaaatctccaacctgctggtggccactaagaaagcc caagagtggcagcccgtctaccccatgagccagctgagttttgatcggatcctcaagaaa gatattatgcaaggcgagcaccttgggagaggcacacggacacacatctactctgggacc ctcatggattacaaggatgacgaaggaactgccgaagagaagagaataaaagtgatcctc aaagtgttagaccccagccacagggacatttccctggccttctttgaggcagccagcatg atgagacaggtctcccataaacacatcgtgtacctctatggcgtctgtgtccgagacgtg gagaatatcatggtggaagagtttgtggagggggggcccctggacctcttcatgcaccgg aaaagtgatgtcctcaccacaccctggaaattcaaagttgccaagcagctggccagcgcc ctgagttacttggaggataaagacctggtccacggaaacgtgtgcactaaaaacctcctc ctggcccgcgagggcattgacagcgagtgcggcccgttcatcaagctcagtgaccccggc atccccatcacggtgctgtccagacaagagtgcatagaacgaatcccatggattgctccc gagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggaacc acactctgggaaatctgctacaatggcgagatccccttgaaagacaagacactgattgag aaagagaggttctacgaaagccggtgcaggccagtgacaccgtcttgtaaggagctggct gaccttatgacccgctgcatgaactacgaccccaaccagagaccgttcttccgagccatc atgagagacatcaacaagctggaggagcagaatccagacatcgtatcagaaaaaaagcca gcaaccgaagtggatcccacacattttgaaaagcggttcttaaagaggatccgtgacttg ggagagggccacttcgggaaggttgagctctgcagatacgaccccgagggggacaataca ggggagcaggtggctgtcaaatctctgaagcctgagagtggagggaaccacatagctgat ctgaagaaggaaatcgaaatcttaagaaacctttatcacgagaacattgtgaagtacaaa ggcatctgcaccgaggacggaggaaatggtattaagctcatcatggaatttctgccttcg ggaagccttaaggaatatcttccaaagaacaagaacaaaattaacctcaaacagcagtta aaatatgctgttcagatttgcaaggggatggactacctgggttctcggcagtacgttcac cgggacttggcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattggagac ttcggtctgaccaaagcaattgaaactgataaggagtattacacagtcaaggacgaccgg gacagccctgtgttctggtatgctccagaatgtttaattcagtgtaaattttatatcgcc tctgatgtctggtcttttggagtgactctgcacgagctgcttacttactgtgattcagat tccagtcccatggcattgttcctgaaaatgataggcccaactcatggccagatgacggta acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacctaactgtcca gaagaggtttatcaactcatgagaaaatgctgggaattccaaccatctaatcggacaacc tttcaaaaccttattgaaggatttgaagcacttttaaaataa

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