Canis lupus familiaris (dog): 100856448 Help Entry 100856448         CDS       T01007                                  Symbol HK2 Name (RefSeq) hexokinase-2   KO K00844   hexokinase [EC:2.7.1.1] Organism cfa  Canis lupus familiaris (dog) Pathway cfa00010   Glycolysis / Gluconeogenesis cfa00051   Fructose and mannose metabolism cfa00052   Galactose metabolism cfa00500   Starch and sucrose metabolism cfa00520   Amino sugar and nucleotide sugar metabolism cfa00524   Neomycin, kanamycin and gentamicin biosynthesis cfa01100   Metabolic pathways cfa01200   Carbon metabolism cfa01250   Biosynthesis of nucleotide sugars cfa04066   HIF-1 signaling pathway cfa04910   Insulin signaling pathway cfa04930   Type II diabetes mellitus cfa04973   Carbohydrate digestion and absorption cfa05230   Central carbon metabolism in cancer Module cfa_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate cfa_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose cfa_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:cfa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     100856448 (HK2)    00051 Fructose and mannose metabolism     100856448 (HK2)    00052 Galactose metabolism     100856448 (HK2)    00500 Starch and sucrose metabolism     100856448 (HK2)    00520 Amino sugar and nucleotide sugar metabolism     100856448 (HK2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     100856448 (HK2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     100856448 (HK2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100856448 (HK2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     100856448 (HK2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     100856448 (HK2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100856448 (HK2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:cfa04131]     100856448 (HK2) Enzymes [BR:cfa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      100856448 (HK2) Membrane trafficking [BR:cfa04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     100856448 (HK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 FGGY_N Motif Other DBs NCBI-GeneID:  100856448 NCBI-ProteinID:  XP_038309165 Ensembl:  ENSCAFG00000008265 VGNC:  41699 LinkDB All DBs Position 17:complement(47929800..47991763) Genome browser AA seq 917 aa AA seqDB search MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDENLLEISKRFRKEMEKGLGATTHPTAS VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQKVEMENQIYAIPEDLMR GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCVQTKLDESFLVSWTKGFKSSGV EGKDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGILDDFRTEFDQEIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFGGKLSPGLLATGQFETKDVSDIEGEKDGIRKAREVLVRLG IDPTQEDCVATHRVCQIVSTRSASLCAATLAAVLRRIKENKGEERLRSTIGVDGSVYKKH PHFAKRLHKTVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQNTLESLKLS REQLLEVKRRMNVEMGRGLSKETHAIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVKNGKRRGVEMHNKIYSIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD IRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKIMHETVKDLAPKCDVSFLESEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgatcgcctcgcatctgctcgcctacttcttcacggagctcaaccacgaccaggtgcag aaggtcgaccagtatctctaccacatgcgtctttctgatgagaaccttctggagatctct aagcggttccgcaaggagatggagaaggggcttggagccaccacccaccccaccgcttca gtgaaaatgctgcccacctttgtgaggtctactccagatgggacagaacatggagagttc ctggctctggaccttggagggacaaacttccgtgtgcttcgggtaagagtaacagacaac gggctccagaaggtcgagatggagaaccagatctatgccattcccgaggacctcatgaga ggcagcggcacccagctgtttgaccacattgccgaatgcctggctaacttcatggataag ctgcaaatcaaagacaagaagctccccttgggttttactttctcattcccctgtgtccaa acgaaactagatgagagtttcctggtctcctggacaaaggggttcaagtccagtggtgtg gaaggcaaagatgtggttactctgattcggaaggccatccagaggagaggggactttgat attgatatcgtggccgtagtgaatgacacagttgggaccatgatgacctgtggttatgat gaccagaattgtgagattggtctcattgtaggcacgggcagcaatgcctgctacatggaa gagatgcgtcacattgacatggtggagggcgacgaggggcggatgtgtatcaacatggaa tggggggcttttggagacgacggcatactcgatgacttccgcactgagtttgatcaggag atcgacatgggctccctgaaccccgggaaacaactatttgagaagatgatcagtgggatg tacatgggagaactggtgaggcttatcttggtgaagatggccaaggaagagctacttttc ggggggaagctcagcccagggctccttgctactggccagtttgagaccaaagacgtttca gatatcgaaggggaaaaggatggcatccggaaggcccgtgaggtgctggtgcggctgggc atagacccgacacaggaggactgcgtggctactcaccgagtctgccagattgtgtctaca cgctcagccagcctgtgtgcagccaccctggcagccgtgctgcggcgcatcaaggagaac aagggcgaggagcggctgcgctccaccattggggttgatggctccgtctacaagaagcac ccacatttcgccaaacgtcttcacaagaccgtgaggcgcttggtgcccgactgtgacgtc cgcttcctgcgttccgaggatggcagtggcaagggggcggccatggtgacggcagtggcc taccggctggctgaccaacaccgagctcgccagaataccctggagtctctgaagctgagc cgcgagcagctactggaggtcaagaggaggatgaacgtagaaatggggcgaggtctgagc aaggagactcatgccattgcccccgtcaagatgctgcctacttacgtgtgcgccacccct gatggcacagagaaaggtgacttcctggccttggaccttggaggtaccaatttccgggtc ctgctggtgcgtgtgaagaatggaaagcgacgcggcgtggagatgcacaacaagatctac tctatcccgcaggaggtcatgcatggcactggggatgagctctttgaccatattgtccag tgcatcgccgacttccttgagtacatgggcatgaaaggcgtgtccctgcctctgggtttc accttctccttcccctgccagcagaacagcctggatgagagcatcctcctcaagtggact aaaggcttcaaggcatcaggctgcgagggagaggatgtggtcactctgctgaaggaagcc atccaccggcgagaggagtttgacctggacgtggttgctgtggtgaacgacacagttggg actatgatgacctgtggctatgaagaccctcactgtgaagtcggcctcattgttggcacg ggcagcaatgcctgctacatggaggagatgcggaacgtggagctggtggagggggaagag ggtcggatgtgtgtcaacatggaatggggggccttcggggacaatggatgccttgacgac atccgcacagagtttgatgtggctgtggatgagctctcccttaaccccggcaaacagaga ttcgagaaaatgatcagtggaatgtacctgggtgagattgtccggaacatcctcatcgat ttcaccaagcgtgggctgcttttccgtggccgcatctctgagcggctcaagacaagagga atctttgaaaccaagtttctgtctcagattgagagtgactgcttggccctgctgcaggtc cgtgccatcctgcaccacctggggctcgagagcacctgtgatgacagcatcattgtcaaa gaggtgtgcactgtggtggcacggcgggcagcccagctctgtggtgcaggcatggccgcc gtggtggacaaaatacgagaaaaccgtgggctggacaccctcaaagtgacagtgggcgtg gatgggaccctctacaagctccatcctcactttgccaaaatcatgcatgagacagtgaag gacctggctccgaaatgtgacgtgagctttctcgagtcagaggacggcagcgggaagggg gccgctctcatcaccgccgtggcctgccgcatccgcgaggctggacagcgatag

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