KEGG   Canis familiaris (dog): 442942Help
Entry
442942            CDS       T01007                                 

Gene name
PTGS2, COX-2
Definition
(RefSeq) prostaglandin-endoperoxide synthase 2
  KO
K11987  
prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
Organism
cfa  Canis familiaris (dog)
Pathway
Arachidonic acid metabolism
Metabolic pathways
NF-kappa B signaling pathway
VEGF signaling pathway
IL-17 signaling pathway
TNF signaling pathway
Retrograde endocannabinoid signaling
Serotonergic synapse
Ovarian steroidogenesis
Oxytocin signaling pathway
Regulation of lipolysis in adipocytes
Leishmaniasis
Human papillomavirus infection
Kaposi's sarcoma-associated herpesvirus infection
Pathways in cancer
Chemical carcinogenesis
MicroRNAs in cancer
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:cfa00001]
 Metabolism
  Lipid metabolism
   00590 Arachidonic acid metabolism
    442942 (PTGS2)
 Environmental Information Processing
  Signal transduction
   04370 VEGF signaling pathway
    442942 (PTGS2)
   04064 NF-kappa B signaling pathway
    442942 (PTGS2)
   04668 TNF signaling pathway
    442942 (PTGS2)
 Organismal Systems
  Immune system
   04657 IL-17 signaling pathway
    442942 (PTGS2)
  Endocrine system
   04923 Regulation of lipolysis in adipocyte
    442942 (PTGS2)
   04913 Ovarian Steroidogenesis
    442942 (PTGS2)
   04921 Oxytocin signaling pathway
    442942 (PTGS2)
  Nervous system
   04726 Serotonergic synapse
    442942 (PTGS2)
   04723 Retrograde endocannabinoid signaling
    442942 (PTGS2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    442942 (PTGS2)
   05206 MicroRNAs in cancer
    442942 (PTGS2)
   05204 Chemical carcinogenesis
    442942 (PTGS2)
   05222 Small cell lung cancer
    442942 (PTGS2)
  Infectious diseases
   05167 Kaposi's sarcoma-associated herpesvirus infection
    442942 (PTGS2)
   05165 Human papillomavirus infection
    442942 (PTGS2)
   05140 Leishmaniasis
    442942 (PTGS2)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.99  Miscellaneous
    1.14.99.1  prostaglandin-endoperoxide synthase
     442942 (PTGS2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
UniProt: 
LinkDB All DBs
Position
7
AA seq 604 aa AA seqDB search
MLARALVLCAALAVVRAANPCCSHPCQNQGICMSTGFDQYKCDCTRTGFYGENCSTPEFL
TRIKLYLKPTPNTVHYILTHFKGVWNIVNNIPFLRNTIMKYVLTSRSHLIESPPTYNVNY
GYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGKKELPDSKEIVEKFLLRRKFIPDPQGT
NMMFAFFAQHFTHQFFKTDHKRGPAFTKGLGHGVDLNHVYGETLDRQHKLRLFKDGKMKY
QVIDGEVYPPTVKDTQVEMIYPPHVPEHLQFAVGQEVFGLVPGLMMYATIWLREHNRVCD
VLKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQ
NRIAAEFNTLYHWHPLLPDTLQIDDQEYNFQQFIYNNSILLEHGLTQFVESFSRQIAGRV
AGGRNVPAAVQQVAKASIDQSRQMKYQSLNEYRKRFRLKPYTSFEELTGEKEMAAGLEAL
YGDIDAMELYPALLVEKPRPDAIFGETMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGEV
GFKIINTASIQSLICNNVKGCPFTAFSVQDGQLTKTVTINASSSHSGLDDINPTVLLKER
STEL
NT seq 1815 nt NT seq  +upstreamnt  +downstreamnt
atgctggcccgcgccctggtgctctgcgccgccctggcggtcgtccgcgcagcaaatcct
tgctgttcccacccatgtcaaaaccaaggtatttgtatgagcacaggatttgaccagtat
aagtgtgactgtacccgaacaggattctacggcgaaaactgctcaacaccggaatttctg
acaagaataaaattatacctgaaacccactccaaatacagtacactacatacttacccac
ttcaagggagtctggaacattgtcaataacatccccttcctgcgaaatacaattatgaaa
tatgtgttgacatcccggtcacatttgattgagagtccaccaacttataatgtgaactac
ggctataaaagctgggaagccttttctaacctctcctattataccagagctcttccccct
gtacctgatgactgtccaacacccatgggtgtgaaaggcaagaaagagcttcctgattca
aaagagattgtggaaaagtttcttctgcgaagaaagttcattcctgatccccaaggcacc
aatatgatgtttgcattctttgcccagcactttacccatcaatttttcaagacagatcat
aagcgaggaccagctttcaccaaaggattgggccatggggtggacttaaatcatgtttat
ggggaaactttggatagacaacataaactgcgccttttcaaggatggaaaaatgaaatat
caggtaattgatggagaggtgtatcctcctaccgtcaaagatactcaggtcgagatgatc
tacccacctcatgttcctgaacacctgcagtttgctgtgggccaggaggtctttggtctg
gtgcctggtctgatgatgtatgccaccatttggctgcgggagcataacagagtgtgtgat
gtgcttaaacaggagcacccagaatgggatgatgagcggttattccagacgagcaggcta
atacttataggagaaaccattaagattgtgattgaagactatgtacaacacttgagtggc
tatcacttcaagctgaagtttgacccagagctgcttttcaaccaacaattccagtaccaa
aaccgcattgctgctgagtttaacacactctaccactggcatcccctcctgcctgacacc
ttgcaaatagatgaccaggagtacaatttccaacagtttatctacaacaactctatatta
ttggaacatggccttacccagtttgtggaatcattcagcaggcaaattgctggcagggtt
gccggtggcaggaatgttccagctgcagtacaacaagtagcaaaagcttcgattgaccag
agcagacagatgaaataccagtctcttaatgagtatcgcaaacgctttaggctgaagccc
tatacatcattcgaagaacttacaggagagaaggaaatggctgcggggttggaggccctt
tatggtgatattgatgccatggagctgtatcctgccctcttggtagaaaagcctcgtcca
gatgccatctttggtgagaccatggtagaaatgggagcaccattctccttgaaaggactt
atgggtaatcccatctgttcacctgactactggaagcctagcacctttggtggagaagta
ggctttaaaatcatcaacactgcctcaatccagtctctcatctgcaataacgtgaagggc
tgtccattcactgcattctctgttcaagacggacaactcaccaaaacagtcaccattaat
gcaagctcttcgcactccggtctagatgacatcaatcccacagtcctactgaaagaacgg
tcaactgaactatag

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