Canis lupus familiaris (dog): 475035 Help Entry 475035            CDS       T01007                                  Symbol HDAC2 Name (RefSeq) histone deacetylase 2 isoform X1   KO K06067   histone deacetylase 1/2 [EC:3.5.1.98] Organism cfa  Canis lupus familiaris (dog) Pathway cfa03082   ATP-dependent chromatin remodeling cfa03083   Polycomb repressive complex cfa04110   Cell cycle cfa04213   Longevity regulating pathway - multiple species cfa04330   Notch signaling pathway cfa04350   TGF-beta signaling pathway cfa04613   Neutrophil extracellular trap formation cfa04919   Thyroid hormone signaling pathway cfa05016   Huntington disease cfa05031   Amphetamine addiction cfa05034   Alcoholism cfa05165   Human papillomavirus infection cfa05169   Epstein-Barr virus infection cfa05200   Pathways in cancer cfa05202   Transcriptional misregulation in cancer cfa05203   Viral carcinogenesis cfa05206   MicroRNAs in cancer cfa05220   Chronic myeloid leukemia Brite KEGG Orthology (KO) [BR:cfa00001]  09120 Genetic Information Processing   09126 Chromosome    03082 ATP-dependent chromatin remodeling     475035 (HDAC2)    03083 Polycomb repressive complex     475035 (HDAC2)  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     475035 (HDAC2)    04350 TGF-beta signaling pathway     475035 (HDAC2)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     475035 (HDAC2)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     475035 (HDAC2)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     475035 (HDAC2)   09149 Aging    04213 Longevity regulating pathway - multiple species     475035 (HDAC2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     475035 (HDAC2)    05202 Transcriptional misregulation in cancer     475035 (HDAC2)    05206 MicroRNAs in cancer     475035 (HDAC2)    05203 Viral carcinogenesis     475035 (HDAC2)   09162 Cancer: specific types    05220 Chronic myeloid leukemia     475035 (HDAC2)   09172 Infectious disease: viral    05169 Epstein-Barr virus infection     475035 (HDAC2)    05165 Human papillomavirus infection     475035 (HDAC2)   09164 Neurodegenerative disease    05016 Huntington disease     475035 (HDAC2)   09165 Substance dependence    05031 Amphetamine addiction     475035 (HDAC2)    05034 Alcoholism     475035 (HDAC2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:cfa03036]     475035 (HDAC2) Enzymes [BR:cfa01000]  3. Hydrolases   3.5  Acting on carbon-nitrogen bonds, other than peptide bonds    3.5.1  In linear amides     3.5.1.98  histone deacetylase      475035 (HDAC2) Chromosome and associated proteins [BR:cfa03036]  Eukaryotic type   Histone modification proteins    HDACs (histone deacetylases)     Class I HDACs      475035 (HDAC2)    HDAC complexes     Sin3A-HDAC complex      475035 (HDAC2)     BRAF-HDAC complex      475035 (HDAC2)     REST complex      475035 (HDAC2)     SHIP complex      475035 (HDAC2)     MiDAC complex      475035 (HDAC2)    Polycomb repressive complex (PRC) and associated proteins     Noncanonical PRC1 (PRC1.6)      475035 (HDAC2)   Heterochromatin formation proteins    Other heterochromatin formation proteins     475035 (HDAC2)   Chromatin remodeling factors    NuRD complex     475035 (HDAC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hist_deacetyl Motif Other DBs NCBI-GeneID:  475035 NCBI-ProteinID:  XP_013973700 Ensembl:  ENSCAFG00000004049 VGNC:  49101 LinkDB All DBs Position 12:complement(69799259..69828714) Genome browser AA seq 509 aa AA seqDB search MHRDPGPAAGRPGSPHPRSGPQRGRRPRLRPALAGVSAGDIGNYYYGQGHPMKPHRIRMT HNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGE DCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVL AILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGK GKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTV KGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFG PDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDG EDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKA DVKEEDKSKDSSGEKTDTKGAKSEQLSNP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgcaccgggacccgggtcctgcagccggcaggcccgggtccccccatccgcgctccggc ccacagagggggcggcgaccgcgcctgcgccccgcgctcgctggggtctcggcaggtgat attggaaattactattatggacagggtcatcccatgaaacctcatagaatccgcatgacc cataacttgctgctaaattatggcttatatagaaaaatggaaatatacaggccccacaaa gccactgctgaagaaatgacaaaataccacagtgatgagtacatcaaatttctacgttca ataagaccagataacatgtctgagtatagtaagcagatgcagagatttaatgttggagaa gactgtccagtgtttgatggactctttgagttttgccagctctcaacgggtggctcagtt gctggtgctgtgaagttaaaccgacaacaaactgatatggctgttaactgggctggagga ttacatcatgctaagaaatcagaagcatcaggattctgttatgttaatgatattgtactt gccatccttgaattactaaagtatcatcagagagtgttatatattgatattgatatccat catggtgatggtgttgaagaagctttttacacaacagatcgtgtaatgactgtatcattc cataaatatggggagtactttcctggaacaggagacttgagggatattggtgcaggaaaa ggcaaatactatgctgtcaattttccaatgagagatggtatagatgatgaatcctatggg caaatatttaagcctattatctcaaaagtgatggagatgtatcaacccagtgctgtggtg ctacagtgtggtgcagactcactgtctggtgataggcttggttgcttcaatctgacagtc aaaggtcatgctaaatgtgtagaagttgtgaaaactttcaatttaccattactgatgctt gggggaggtggatacacaattcgtaatgttgctcgatgttggacgtacgagactgcggtt gcccttgattgtgagattcccaacgaactgccatataatgattactttgagtattttggc ccggacttcaaactgcatattagtccttcaaatatgacaaaccagaacactccagaatat atggaaaagataaaacagcgtttatttgaaaatttacgcatgttacctcatgcacctggc gtccagatgcaagcaatcccagaagacgctgttcatgaagacagtggagatgaagatgga gaagatccagacaagagaatttctattcgagcatcagacaaacggatagcttgtgatgaa gaattctcagattctgaggatgaaggtgaaggaggacgtagaaatgtggccgatcataag aaaggagcaaagaaagctagaattgaagaagacaagaaggaaacagaggacaaaaaagca gatgttaaggaagaagataaatccaaggacagtagtggtgaaaaaacagataccaaagga gccaaatcagaacagctcagcaacccttga

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