Canis lupus familiaris (dog): 475511
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Entry
475511 CDS
T01007
Symbol
EZH2
Name
(RefSeq) histone-lysine N-methyltransferase EZH2 isoform X6
KO
K11430
[histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:
2.1.1.356
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00310
Lysine degradation
cfa01100
Metabolic pathways
cfa03083
Polycomb repressive complex
cfa05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
475511 (EZH2)
09120 Genetic Information Processing
09126 Chromosome
03083 Polycomb repressive complex
475511 (EZH2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
475511 (EZH2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
cfa03036
]
475511 (EZH2)
Enzymes [BR:
cfa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.356 [histone H3]-lysine27 N-trimethyltransferase
475511 (EZH2)
Chromosome and associated proteins [BR:
cfa03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
475511 (EZH2)
Polycomb repressive complex (PRC) and associated proteins
PRC2.1
475511 (EZH2)
PRC2.2
475511 (EZH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ezh2_MCSS
PRC2_HTH_1
SET
EZH2_WD-Binding
preSET_CXC
Motif
Other DBs
NCBI-GeneID:
475511
NCBI-ProteinID:
XP_003432121
Ensembl:
ENSCAFG00000003411
VGNC:
40541
LinkDB
All DBs
Position
16:3025322..3090857
Genome browser
AA seq
746 aa
AA seq
DB search
MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW
KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF
MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ
YNDDDDDDDGDDPDEREEKQKDLEENRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL
KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH
ATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPN
NSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKM
KPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPA
PAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQ
NFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVS
CKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDK
YMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGE
ELFFDYRYSQADALKYVGIEREMEIP
NT seq
2241 nt
NT seq
+upstream
nt +downstream
nt
atgggccagactgggaagaaatctgagaagggacctgtttgttggcgcaagcgtgtaaaa
tcagagtacatgcggctgcggcagctcaagaggttcaggcgggctgacgaagttaagagt
atgtttagttccaatcgtcagaaaattttggaaagaacggaaatcttaaaccaagaatgg
aaacagcgaaggatacagcctgtgcacatcctgacttctgtgagctcattgcgcgggacc
agggagtgttcagtgaccagtgacttggattttccaacacaagtcatcccattaaagact
ctgaatgcggttgcttcagtacccataatgtattcttggtctccccttcagcagaatttt
atggtggaagatgaaactgttttacataacattccgtatatgggggatgaagttttagat
caggatgggactttcattgaagaactaataaaaaattatgatggaaaagtacatggggat
agagaatgtgggtttataaatgatgaaatttttgtggagttggtgaatgctcttggtcaa
tacaatgatgatgatgatgatgatgatggagatgatcctgatgaaagagaagaaaaacag
aaagatctagaggagaacagagatgataaagaaagccgcccacctcggaaatttccttct
gataaaatttttgaagccatttcctcaatgtttccagataagggcacagcagaagaacta
aaggaaaagtataaagagctcaccgagcagcagctcccaggtgcgcttcctcctgaatgt
accccgaacatcgatggaccaaatgctaaatctgttcagagggagcaaagcttgcattca
tttcatacgcttttctgtaggcgatgttttaaatatgactgcttcctacatccatttcat
gcaacacccaatacttacaagcggaagaacacagaaaccgctctagacaacaaaccttgt
ggaccacagtgttaccagcacttggagggagcaaaggagtttgcggctgccctcactgcc
gagcgcatcaagaccccgcccaagcggcccggcggccgcaggagaggccggcttcccaac
aatagcagccggcccagcacccccaccattaatgtgctggagtccaaggacacggacagt
gacagggaagcggggactgagacgggcggggagaacaacgataaggaggaggaggagaag
aaggacgagacctccagctcctcggaagcaaattctcggtgtcaaacgccaataaagatg
aagccaaacattgagcctcccgagaacgtggagtggagcggcgctgaggcctccatgttc
cgggtgctcatcggtacctactatgacaatttctgtgccattgccaggctcatcgggacc
aagacttgtcggcaggtgtatgagttccgtgtcaaagaatcgagtatcattgctccagcc
ccggccgaggacgtggacacccccccaaggaagaagaagaggaaacaccggttgtgggcg
gcacactgcagaaagatacagctgaaaaaggacggctcctctaaccacgtttacaactat
caaccctgtgaccatccacggcagccttgtgacagttcgtgcccttgtgtgatagcacaa
aatttttgtgagaagttttgtcaatgtagctcagagtgtcaaaaccgctttcctgggtgc
cgctgcaaagcgcagtgcaacacgaagcagtgcccgtgctacctggccgtgcgcgagtgc
gaccccgacctgtgcctcacgtgcggcgccgccgaccactgggacagcaagaacgtgtcc
tgcaagaactgcagcatccagcgcggctccaagaagcacttgctgctggcaccgtctgac
gtggcaggctgggggattttcatcaaagaccctgtgcagaaaaatgaattcatctcggag
tactgtggagagattatttctcaagatgaagcagacagaagagggaaagtctacgataaa
tacatgtgcagctttctcttcaacttgaacaatgattttgtggtggatgcaacccgcaag
ggtaacaaaattcgttttgcaaatcactcagtaaatccaaactgctatgcaaaagttatg
atggttaacggcgatcacaggatagggatttttgctaagagagccatccagaccggtgaa
gagctgttttttgattacagatacagccaggctgatgccctgaagtacgtgggcatcgaa
agagagatggaaatcccttga
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integrated database retrieval system
