Canis lupus familiaris (dog): 489019 Help Entry 489019            CDS       T01007                                  Symbol HKDC1 Name (RefSeq) hexokinase HKDC1 isoform X5   KO K00844   hexokinase [EC:2.7.1.1] Organism cfa  Canis lupus familiaris (dog) Pathway cfa00010   Glycolysis / Gluconeogenesis cfa00051   Fructose and mannose metabolism cfa00052   Galactose metabolism cfa00500   Starch and sucrose metabolism cfa00520   Amino sugar and nucleotide sugar metabolism cfa00524   Neomycin, kanamycin and gentamicin biosynthesis cfa01100   Metabolic pathways cfa01200   Carbon metabolism cfa01250   Biosynthesis of nucleotide sugars cfa04066   HIF-1 signaling pathway cfa04910   Insulin signaling pathway cfa04930   Type II diabetes mellitus cfa04973   Carbohydrate digestion and absorption cfa05230   Central carbon metabolism in cancer Module cfa_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate cfa_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose cfa_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:cfa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     489019 (HKDC1)    00051 Fructose and mannose metabolism     489019 (HKDC1)    00052 Galactose metabolism     489019 (HKDC1)    00500 Starch and sucrose metabolism     489019 (HKDC1)    00520 Amino sugar and nucleotide sugar metabolism     489019 (HKDC1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     489019 (HKDC1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     489019 (HKDC1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     489019 (HKDC1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     489019 (HKDC1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     489019 (HKDC1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     489019 (HKDC1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:cfa04131]     489019 (HKDC1) Enzymes [BR:cfa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      489019 (HKDC1) Membrane trafficking [BR:cfa04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     489019 (HKDC1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  489019 NCBI-ProteinID:  XP_546137 Ensembl:  ENSCAFG00000032754 VGNC:  41701 UniProt:  A0A8C0NLX0 LinkDB All DBs Position 4:20484075..20525712 Genome browser AA seq 917 aa AA seqDB search MFAIHLMAFYFSKLKEDQIKKVDRFLYHMRLSDETLLDIMARFQAEMQKGLGKDTNPTAS VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVSEEGKRNVQMESQFYPTPNEIIR GNGSELFDYIADCLADFMKTRGLKHKKFPLGLTFSFPCRQTKLEEGILLSWTKKFKARGV QDTDVVSCLTKAVKKHKDIDVDILTLVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME DMSNIDLVEGDEGRMCINTEWGAFGDDGTLEDIRTEFDRELDLGSLNPGKQLFEKMISGL YLGELVRIILLKMAKAGLLFGGKKSSALHTKGKIETRHVAAMEKYKEGLANTREILTDLG LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKLERLRTTVGMDGTLYKIH PQYPKRLHKVVRRLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFQLT REQLMDVQGKMRREFEYGLKRDTHLMATVKMLPTYVCGMPDGTEKGKFLALDLGGTNFRV LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGVQLPLGFT FSFPCRQTSIDKGTLIEWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT MMTCGHEDPNCEIGLIAGTGSNMCYMEEMRNIELVEGDEGKMCINTEWGGFGDNGCIDDI RTQYDEKVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI FETKFLSQIESDRLALLQVRSILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLYGAGLAAV VEKKREDQGLEYLKITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTLMLSEDGSGKGA ALITAVAKRLQQAQKEN NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgtttgcaatacacttgatggcattttacttcagcaaactgaaggaggatcagatcaag aaggtggacaggttcctgtatcacatgcggctctccgatgagacccttttggacatcatg gctcgcttccaggctgaaatgcagaagggtctggggaaggacaccaaccccacagcctct gtgaagatgctgcccacctttgtcagggccattccagatggctcagaaaatggggaattt ctttctctggatcttggagggtccaagtttcgtgtcttaaaggtccaagtctctgaagag gggaaaagaaacgtccagatggagagtcagttctacccaacacccaatgaaattatccga gggaatggctcagagctgtttgactacatagctgactgtctggcagatttcatgaagacg agagggttgaagcataagaaatttcccctcggcctaaccttttcttttccatgcagacaa actaaattggaagagggtattctgctttcatggaccaagaagtttaaggcacggggagtt caagacacagatgtagtgagttgtctgaccaaagccgtgaaaaaacacaaggacatagac gtggacatcctgaccttggtcaatgacactgtgggaaccatgatgacctgcgcctatgat gatccctactgtgaagttggtgtcatcattggtactggcacgaatgcgtgttacatggag gacatgagcaacattgacctggtggaaggtgacgaggggagaatgtgcatcaacacggag tggggggccttcggagatgatgggactctggaagatatccgtaccgagttcgaccgggag ttagacctcggctctctcaaccctgggaagcaactgtttgagaagatgatcagtggcctg tacctgggcgaacttgtcaggattatattgctgaagatggccaaggcaggtctcctgttt ggtggcaagaaatcctctgctctccacactaagggcaagattgaaacacggcatgtggct gccatggaaaagtataaagaaggccttgccaatacaagagagatcctgacagacctgggc ctggagccttcggaggctgactgcattgcggtccagcacgtctgcaccatcgtatctttc cgttcagccaatctctgtgcagcagccctggcagccatcctgacacgcctccgggagaac aagaagctggagcggctccggaccacagtgggcatggacggcacactctacaagatacac cctcaatatcccaaacgcctgcacaaggtggtaaggaggctggttccgaactgcgacgtc cgcttcctcttgtcagagagcggcagcaccaagggagctgccatggtgacagcggtggcc tcccgggtgcaggcccaaagaaagcagattgacaaggtgctggctttgttccaactgact cgagagcagcttatggatgtgcagggcaagatgcggagggagttcgagtatggactaaaa agggacacccacctgatggccacagtcaagatgctgcccacctatgtctgcgggatgcca gatggcacagagaaaggaaagttccttgccctggatctggggggaaccaacttccgggtc ctcctggtaaagatcagaagtggacggaggtcggtgcgaatgtacaacaagatctttgcc atccccttggagatcatgcagggcaccggtgaggagctatttgaccacatagtgcagtgc atcgctgacttcctggactacatgggcctcaagggagtccaactgcctttgggcttcaca ttctcatttccctgcaggcagacgagcattgacaagggaacactcattgagtggaccaaa ggcttcaaggccactgattgtgaaggggaagacgtggtggacatgctcagggaagccatc aagaggagaaatgagtttgacttagacatagttgcagttgtgaatgatacagtggggacc atgatgacctgtggccatgaagatcctaattgtgagataggcctgattgcaggaacaggc agcaacatgtgctatatggaagagatgaggaacatcgaactggtggaaggggacgaaggg aagatgtgcattaacaccgagtggggaggatttggagataatggctgcatagatgacatc cggacccaatatgatgagaaggtggatgaggggtccttgaaccccggcaaacagagatat gagaagatgaccagcgggatgtatctgggggaaattgtgcggcagatcctgattgacctg accaagcagggtcttctcttccgtgggcagatttcagagcgtctccggaccaggggcatc tttgaaaccaaattcctgtctcagattgaaagcgatcggctagccctcctccaggtcagg agtatcctgcaacagcttggcctagacagcacatgtgaggacagcattgtggtgaaggag gtgtgcggagctgtgtcccggcgggcggcccagctctacggtgcaggcctggcagctgtc gtggagaagaagagggaagaccaggggcttgaatacctgaagatcactgtgggagtggat ggcaccctgtacaagctgcacccacacttttctcggatattgcaggaaaccgtgaaagaa ctagcacctcgatgtgatgtgacgctcatgctgtcagaagatgggagtggaaagggagcc gctctgatcactgctgtggccaagaggttacagcaggcacagaaggagaactag

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