Capra hircus (goat): 102169019 Help Entry 102169019         CDS       T02910                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism chx  Capra hircus (goat) Pathway chx00230   Purine metabolism chx01100   Metabolic pathways chx01522   Endocrine resistance chx04015   Rap1 signaling pathway chx04020   Calcium signaling pathway chx04022   cGMP-PKG signaling pathway chx04024   cAMP signaling pathway chx04062   Chemokine signaling pathway chx04072   Phospholipase D signaling pathway chx04114   Oocyte meiosis chx04211   Longevity regulating pathway chx04213   Longevity regulating pathway - multiple species chx04261   Adrenergic signaling in cardiomyocytes chx04270   Vascular smooth muscle contraction chx04371   Apelin signaling pathway chx04540   Gap junction chx04611   Platelet activation chx04713   Circadian entrainment chx04714   Thermogenesis chx04723   Retrograde endocannabinoid signaling chx04724   Glutamatergic synapse chx04725   Cholinergic synapse chx04727   GABAergic synapse chx04740   Olfactory transduction chx04750   Inflammatory mediator regulation of TRP channels chx04911   Insulin secretion chx04912   GnRH signaling pathway chx04913   Ovarian steroidogenesis chx04914   Progesterone-mediated oocyte maturation chx04915   Estrogen signaling pathway chx04916   Melanogenesis chx04918   Thyroid hormone synthesis chx04921   Oxytocin signaling pathway chx04923   Regulation of lipolysis in adipocytes chx04925   Aldosterone synthesis and secretion chx04926   Relaxin signaling pathway chx04927   Cortisol synthesis and secretion chx04928   Parathyroid hormone synthesis, secretion and action chx04934   Cushing syndrome chx04935   Growth hormone synthesis, secretion and action chx04962   Vasopressin-regulated water reabsorption chx04970   Salivary secretion chx04971   Gastric acid secretion chx04972   Pancreatic secretion chx04976   Bile secretion chx05032   Morphine addiction chx05163   Human cytomegalovirus infection chx05166   Human T-cell leukemia virus 1 infection chx05200   Pathways in cancer chx05207   Chemical carcinogenesis - receptor activation chx05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:chx00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102169019 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102169019 (ADCY3)    04371 Apelin signaling pathway     102169019 (ADCY3)    04020 Calcium signaling pathway     102169019 (ADCY3)    04072 Phospholipase D signaling pathway     102169019 (ADCY3)    04024 cAMP signaling pathway     102169019 (ADCY3)    04022 cGMP-PKG signaling pathway     102169019 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102169019 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     102169019 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102169019 (ADCY3)    04062 Chemokine signaling pathway     102169019 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     102169019 (ADCY3)    04923 Regulation of lipolysis in adipocytes     102169019 (ADCY3)    04912 GnRH signaling pathway     102169019 (ADCY3)    04913 Ovarian steroidogenesis     102169019 (ADCY3)    04915 Estrogen signaling pathway     102169019 (ADCY3)    04914 Progesterone-mediated oocyte maturation     102169019 (ADCY3)    04921 Oxytocin signaling pathway     102169019 (ADCY3)    04926 Relaxin signaling pathway     102169019 (ADCY3)    04935 Growth hormone synthesis, secretion and action     102169019 (ADCY3)    04918 Thyroid hormone synthesis     102169019 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     102169019 (ADCY3)    04916 Melanogenesis     102169019 (ADCY3)    04925 Aldosterone synthesis and secretion     102169019 (ADCY3)    04927 Cortisol synthesis and secretion     102169019 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102169019 (ADCY3)    04270 Vascular smooth muscle contraction     102169019 (ADCY3)   09154 Digestive system    04970 Salivary secretion     102169019 (ADCY3)    04971 Gastric acid secretion     102169019 (ADCY3)    04972 Pancreatic secretion     102169019 (ADCY3)    04976 Bile secretion     102169019 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     102169019 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     102169019 (ADCY3)    04727 GABAergic synapse     102169019 (ADCY3)    04725 Cholinergic synapse     102169019 (ADCY3)    04723 Retrograde endocannabinoid signaling     102169019 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     102169019 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     102169019 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     102169019 (ADCY3)    04213 Longevity regulating pathway - multiple species     102169019 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     102169019 (ADCY3)    04714 Thermogenesis     102169019 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102169019 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     102169019 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102169019 (ADCY3)    05163 Human cytomegalovirus infection     102169019 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     102169019 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102169019 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102169019 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102169019 (ADCY3) Enzymes [BR:chx01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102169019 (ADCY3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  102169019 NCBI-ProteinID:  XP_005687005 EnsemblRapid:  ENSCHIG00000025812 UniProt:  A0A452G4N4 LinkDB All DBs Position 11:74037527..74125235 Genome browser AA seq 1145 aa AA seqDB search MPRTQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSADKLAPLAVAGVGLVLDII LFVLCKKGLLPNRVTRRVVPYLLWLLISAQVFSYLGLNFSRAHAASDTVGWQAFFVFSFF ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLKGVRLLREILANVFLYLCAIVVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGEGGSRCD YLEEKGIETYLIIASKPEVKKTAAQNGLNGSALLNGAPPSSKPSSPALIETKESNGSIHT SSSISEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTAVVEILIDPWLMTN YVTFVVGEALLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYYTGPTNGTAEMQVEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLIAGAVAVINVYAWRPIFDDYDHKRFQQHNFPMVALEKMQVFSTSGLNGTDRLPLVPSK YSMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKEEKSDKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNGASITLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggacccagggcttctccgagcccgagtactccgctgagtactcggccgagtac tctgtcagcctgccttcggaccctgaccgcggggtgggccggacccatgaaatctcagtt cggaactcggggtcgtgcctctgcttacctcgcttcatgcgactgaccttcgtaccagag tccttggagaatctgtaccagacttacttcaagaggcagcgccatgagaccctgctggtg ctggtggtctttgcggccctcttcgactgctatgtggtggtcatgtgcgccgtggtcttc tctgctgacaagctggcccccctcgccgtggccggggttgggctggtgttggacatcatc cttttcgtgctctgcaaaaaggggctgctccccaaccgggtcactcggagagtggtgccc tacctgctgtggctgctgatatcagcccaggtcttctcctacctgggcctgaacttctcc cgtgcccatgcggccagcgacacggtgggctggcaggccttcttcgtcttctccttcttc atcacgctgccgctcagcctcagccccattgtcatcatctccgtggtctcctgcgttgtg cacacactcgtcttgggggtcaccgtggcccagcagcagcaggatgggctgaagggagtg cgcttgctgagggagattctggccaacgtcttcctctacctgtgcgccatcgtcgtgggc atcatgtcctactacatggcagaccgcaagcaccgcaaggccttcctggaggcccgccag tctctggaggtgaagatgaacctggaggagcagagccagcagcaggagaaccttatgctc tccatcctgcccaagcacgtggccgacgagatgctgaaggacatgaagaaggacgagagc cagaaagaccagcagcagttcaacaccatgtacatgtaccgccatgagaacgtcagcatc ctctttgctgatatcgtgggtttcacccagctgtcctcagcctgcagtgcccaggagctt gtgaagctgctcaatgagctctttgcccgctttgacaagctggcagctaaataccaccag ctgcggattaagatcctgggtgactgctactactgcatctgcgggctgcctgactaccgg gaggaccacgctgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgggagaagacgaagactggggtggacatgcgagtgggggtgcacacgggcaccgtg ctggggggcgtcctcggccagaaacgctggcagtacgatgtgtggtccaccgacgtcacc gtggccaacaagatggaggctggcggcatccctgggcgcgtgcacatctcccagagcacc atggactgcctgaaaggagagtttgacgtggagccgggcgaggggggcagtcgctgtgat tacctggaagagaagggcattgagacctacctcatcatcgcttccaagccagaggtgaag aagacagctgcccaaaacggcctcaacggctcggccctgctgaacggagcgccgccttcc tcaaagcccagctcccctgccctcattgagaccaaggagtccaacgggagcattcacacc agcagctctatatctgaggagcccgaggagcaagatgcccaggccgacaacccctcgttc cccaaccctcgccggaggctgcgccttcaggacctggctgatcgcgtggtggatgcctct gaggacgagcatgagctcaaccagctactcaacgaggcactgctcgagcgagagtctgcc caggtagtgaagaagagaaacaccttcctcctgtctatgcggttcatggaccctgagatg gaaacccgctactcagtggagaaggagaagcagagcggggctgccttcagctgctcctgc gttgtcctgctctgcacggccgtggtggagatcctcattgacccctggctcatgacgaac tatgtgacctttgtggttggggaggctctgctcctgatcctgacgatctgctcactggct gccatctttccacgggcctttcctaagaagctcgtggccttctctacttggatcgaccgg acacgctgggccaggaacacctgggccatgctggccatcttcattcttgtcatggcaaac gtggtggacatgctcagctgtctccagtactacacaggccctaccaacggcaccgcagag atgcaggtggaggacggctgcgtggagaaccccaagtactacaactacgtggccgtgctg tccctcatcgctaccatcatgctggtgcaggtcagccacatggtcaagctcacactcatg ctgctcatcgcgggggctgtggctgtcatcaacgtctacgcctggcgccccatctttgat gactacgaccacaaacgcttccagcaacacaactttccaatggtggccttagagaagatg caagtgttttccacctcgggactcaatggcactgacaggctgcccctggtgccgtctaag tactcgatgacagtgatgatcttcgtcatgatgctgagcttttactacttctcccgacac gtggaaaagctggcacggacactgttcttgtggaagattgaggtccacgaccagaaggaa cgtgtctatgagatgcgacgctggaacgaagccttggtcaccaacatgctgcctgagcac gtggcacgccatttcctggggtccaagaagagagatgaggagctgtacagccagtcttat gatgagattggagttatgtttgcctccctgcccaattttgccgacttctacacagaggag agcatcaataatggcggcattgagtgtctgcgcttcctcaatgagatcatctcagatttt gactctcttctggacaatcccaagttccgggtcatcaccaagatcaagaccattggtagc acctacatggcagcttcaggagtcaccccagatgtcaacaccaatggctttaccagctcc aacaaggaggagaagtcagacaaggagcgctggcagcacctggcagacctggctgacttt gcgctggccatgaaggacacgctcaccaacatcaataaccagtccttcaacaacttcatg ctgcgcattggaatgaacaaaggaggggtcctggctggggtcattggagcccggaaacca cactatgacatctggggcaacacagtcaatgtagccagcaggatggagtccacaggggtc atgggcaacatccaggtggtggaagaaacccaagtcatccttcgagagtatggcttccgc ttcgtgaggagagggcccatctttgtgaaagggaagggggaactgctaacctttttcttg aagggccgagacaagctggccacgttccctaacggcgcctcaatcacactgcctcaccag gtagtagacaactcctga

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