KEGG   Canis lupus dingo (dingo): 112673919
Entry
112673919         CDS       T08371                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
clud  Canis lupus dingo (dingo)
Pathway
clud01521  EGFR tyrosine kinase inhibitor resistance
clud01522  Endocrine resistance
clud04012  ErbB signaling pathway
clud04015  Rap1 signaling pathway
clud04062  Chemokine signaling pathway
clud04137  Mitophagy - animal
clud04144  Endocytosis
clud04360  Axon guidance
clud04370  VEGF signaling pathway
clud04510  Focal adhesion
clud04520  Adherens junction
clud04530  Tight junction
clud04540  Gap junction
clud04611  Platelet activation
clud04613  Neutrophil extracellular trap formation
clud04625  C-type lectin receptor signaling pathway
clud04727  GABAergic synapse
clud04750  Inflammatory mediator regulation of TRP channels
clud04810  Regulation of actin cytoskeleton
clud04912  GnRH signaling pathway
clud04915  Estrogen signaling pathway
clud04917  Prolactin signaling pathway
clud04919  Thyroid hormone signaling pathway
clud04921  Oxytocin signaling pathway
clud04926  Relaxin signaling pathway
clud05100  Bacterial invasion of epithelial cells
clud05135  Yersinia infection
clud05152  Tuberculosis
clud05161  Hepatitis B
clud05163  Human cytomegalovirus infection
clud05167  Kaposi sarcoma-associated herpesvirus infection
clud05168  Herpes simplex virus 1 infection
clud05203  Viral carcinogenesis
clud05205  Proteoglycans in cancer
clud05207  Chemical carcinogenesis - receptor activation
clud05208  Chemical carcinogenesis - reactive oxygen species
clud05219  Bladder cancer
clud05417  Lipid and atherosclerosis
clud05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:clud00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    112673919 (SRC)
   04015 Rap1 signaling pathway
    112673919 (SRC)
   04370 VEGF signaling pathway
    112673919 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    112673919 (SRC)
   04137 Mitophagy - animal
    112673919 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112673919 (SRC)
   04520 Adherens junction
    112673919 (SRC)
   04530 Tight junction
    112673919 (SRC)
   04540 Gap junction
    112673919 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    112673919 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    112673919 (SRC)
   04613 Neutrophil extracellular trap formation
    112673919 (SRC)
   04625 C-type lectin receptor signaling pathway
    112673919 (SRC)
   04062 Chemokine signaling pathway
    112673919 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    112673919 (SRC)
   04915 Estrogen signaling pathway
    112673919 (SRC)
   04917 Prolactin signaling pathway
    112673919 (SRC)
   04921 Oxytocin signaling pathway
    112673919 (SRC)
   04926 Relaxin signaling pathway
    112673919 (SRC)
   04919 Thyroid hormone signaling pathway
    112673919 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    112673919 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112673919 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    112673919 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    112673919 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    112673919 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    112673919 (SRC)
   05203 Viral carcinogenesis
    112673919 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    112673919 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    112673919 (SRC)
   05168 Herpes simplex virus 1 infection
    112673919 (SRC)
   05163 Human cytomegalovirus infection
    112673919 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112673919 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    112673919 (SRC)
   05152 Tuberculosis
    112673919 (SRC)
   05100 Bacterial invasion of epithelial cells
    112673919 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112673919 (SRC)
   05418 Fluid shear stress and atherosclerosis
    112673919 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112673919 (SRC)
   01522 Endocrine resistance
    112673919 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:clud01001]
    112673919 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:clud04131]
    112673919 (SRC)
Enzymes [BR:clud01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     112673919 (SRC)
Protein kinases [BR:clud01001]
 Non-receptor tyrosine kinases
  SRC family
   112673919 (SRC)
Membrane trafficking [BR:clud04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    112673919 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    112673919 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    112673919 (SRC)
  Macropinocytosis
   Kinases
    112673919 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 112673919
NCBI-ProteinID: XP_025325808
Ensembl: ENSCAFG00020012489
LinkDB
Position
24:26020870..26070999
AA seq 553 aa
MGSNKSKPKDASQRRRSLEPAENTHGGGGGAFPTSQTPSKPASADGHRGPSTAFPSAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq 1662 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccaacggcgccgcagcctagagcca
gctgagaacacccacggtggcggcgggggtgccttccccacctcacagacacccagcaag
ccagcctccgctgatggccaccgaggccccagtacagccttcccttccgcagctgctgag
cccaagctgtttgggggcttcaactcctcggacacggtcacctccccgcagcgggcgggg
ccgctggctggtggagtgaccacctttgtggccctctatgactatgagtctcggacagag
accgatctgtccttcaagaaaggggagcggctccagattgtcaacaacacgaggaaagtg
gatgtcagccagacctggttcacattcagatggctgcaaagagagggtgactggtggctg
gcccactcgctcagcacgggacagacaggctacatccccagcaactacgtggcgccctct
gactctatccaggctgaggagtggtactttggcaagatcaccagacgggagtcagagcgg
ttattgctcaatgcagagaacccgagagggaccttcctggtgcgagaaagcgagaccacg
aaaggcgcctactgcctctctgtgtcggatttcgacaacgccaagggcctcaatgtgaag
cactacaagatccgcaagctcgacagtggtggcttctacatcacctcgcgcacacagttc
aacagcctgcagcagctggtggcctactactccaaacatgccgatggcctgtgccaccgc
ctcaccaccgtgtgccccacatccaagccacagactcaggggctggccaaggatgcctgg
gagatccctcgggagtctctgcggctggaggtcaaactgggccagggctgtttcggagag
gtgtggatgggaacctggaacggaaccaccagggtggccatcaaaaccctgaagccaggc
acgatgtctccagaggccttcctgcaggaggctcaggtcatgaagaaactgaggcacgag
aagctggtgcagctgtacgcggtggtgtctgaggagcccatctacatcgtcacagagtac
atgagcaaggggagtctgctggacttcctcaagggggagacaggcaagtacctgcgacta
cctcagctggtggacatggccgctcagatcgcctcaggcatggcctacgtggaacggatg
aactacgtccaccgtgacctccgtgctgccaacattctggttggagagaatctcgtgtgc
aaagtggccgactttgggctggcccggctcattgaagacaacgagtacaccgcccggcaa
ggtgccaaattccccatcaagtggacagctccggaagcggccctctatggccgattcacc
atcaagtcagatgtgtggtcctttgggatcctgctgacggagctcacgacaaaggggcgg
gtgccctaccccgggatggtcaaccgtgaggtgcttgaccaggtggaacggggctaccgg
atgccctgcccgcctgagtgtcccgagtccctgcacgacctcatgtgccagtgctggcgg
aaggagcctgaggaacgacccacctttgagtacctgcaggccttcctggaggactacttc
acatccaccgagccccagtaccagccgggagagaacctatag

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