Cavia porcellus (domestic guinea pig): 100302667
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Entry
100302667 CDS
T07777
Symbol
Pde3a
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc00230
Purine metabolism
cpoc01100
Metabolic pathways
cpoc04022
cGMP-PKG signaling pathway
cpoc04024
cAMP signaling pathway
cpoc04924
Renin secretion
cpoc05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100302667 (Pde3a)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
100302667 (Pde3a)
04022 cGMP-PKG signaling pathway
100302667 (Pde3a)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
100302667 (Pde3a)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100302667 (Pde3a)
Enzymes [BR:
cpoc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100302667 (Pde3a)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
TgpA_N
GRP
Motif
Other DBs
NCBI-GeneID:
100302667
NCBI-ProteinID:
XP_003470372
Ensembl:
ENSCPOG00000011292
UniProt:
H0VIU9
LinkDB
All DBs
Position
Unknown
AA seq
1132 aa
AA seq
DB search
MAEAARDRDELDLGRVSPVHPTWPRGALLLQPVRRSWKLSSALCAGSLSFLLAVLVRLVR
EESGRELGPSREAAAAQEEEKEVEEEEEEEEAVPGAEGGVFPGVRGGAPGGGAQLSPWLQ
PSALLLSLLGAFFWMGLYLRRAGVRLPLAVALLAACCGGEALVQIGLGVGEDRLLSLPAA
GVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVALISLERFKVAWRPYLAYLAGVLGILL
ARYVEQILPQSPVEAPREPLGSQRIAGTKEEIPVFKRRRRSSSVVSAEMSGCGSKSHRRT
SLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPTLPPNVC
TSLRAVSNLLSTQLTFPAIHKPRANPMISFSENYTCSDSEESSEKDKLAIPKRLRRSLPP
GLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKLHEAPSSSTVNPDSWNSSVMMTLT
KSRSFTSSYAVSAANHVKAKKQNRPGALAKISPLQSPCSSPLQGTPASSPISKISALQFP
ESAETTAKHGPSSHRTLTYTQSAPDLSPQILDPPVICSSCGRPYSQATPADGPLEKSGEA
TQTSSRTDDTAQVTSDYETNNNSDSSDILQNEDEAECSRESLRKTLACGTYGPEAMIYLD
KPILAPEPLIMDNLDSIMEQLNTWNFPIFDLVENIGKKCGRILSQVSYRLFEDMGLFEAF
KIPVREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTVVNDPGSASDS
DSDSGFTHGHIGYVFSKLYNAADDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFL
VATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLSNLDHVEFKHFRFLVIEAILAT
DLKKHFDFVTKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTEGI
VNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVE
DSDESGDTDDPEEEEEAAVVNEEETCENDESPKKKTFKRRKIYCQITQHLLQNHKMWKKV
IEEEQRLTGIGNPGLDQSAQQHTSEQIQAIEEEDEEKGKPRAEETPAPKPNQ
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atggccgaggccgcccgagaccgggacgagctggacctaggcagggtgagtcctgtgcac
cccacttggccgcggggagccctgctgctgcagccggtccggcgctcgtggaaactttcc
tcggcgctgtgcgcgggctcgctgtcctttctgctggcggtgctggtgcggctggtccgc
gaggagagcggccgagagctggggccgagtcgggaggcggcggcggcgcaggaggaggag
aaggaggtggaggaggaggaggaggaggaggaagcggtcccgggagcagaagggggcgtc
ttccccggcgttcggggaggcgcgcccgggggcggcgcgcagctcagcccctggctgcag
ccctcggcgctgctcctcagtctcctgggtgctttcttctggatgggcttgtacctccgg
cgcgccggggtgcgcctgcctctggccgtcgcgctgctggccgcctgctgcgggggggaa
gcgctagtccagattgggctgggcgtcggggaagatcgcctgctgtcgctgcccgccgcg
ggggtggtgctcagctgcctggccgcggcgacatggctggtgctgaggctgaggctgggc
gtcctcatgatcgccttgactagcgcggtccggaccgtggccctcatttccttggagagg
ttcaaggtcgcctggagaccttacctggcgtacttggccggcgtgctggggatcctcctg
gccaggtacgtggagcagatcttgccgcagtctccggtggaggctcccagggagcctttg
gggtcccagcggattgctgggaccaaggaagagatcccagtgttcaagaggaggcggcgg
tccagctccgtggtgtccgccgagatgtcgggctgtggcagcaagtctcaccgcaggacc
tccctgccctgcatcccccgggagcagctcatggggcattcggaatgggaccacaagcgt
gggcctcgaggttcacagtcctcaggaaccagtatcacggtggacattgctgtgatgggc
gaagctcacggtctcattaccgacctcctggcggaccctactctgcccccaaatgtgtgc
acatccctgcgggctgtgagcaacctactcagcacacagctcaccttcccggccatccac
aagcccagagcgaaccccatgatttccttcagtgaaaactacacctgttctgattcggaa
gagagctcggaaaaagacaagctcgccattcccaagcgcctgaggagaagtttaccacca
ggcttgttgagacgggtttcatcaacctggacaactaccacctcagccacaggcctgccc
accttggagcctgcaccagtccggagggaccgtagtgccagcatcaagctacatgaagca
ccttcatccagtactgttaatcctgattcttggaatagctctgtgatgatgacccttacc
aaaagcagatccttcacctcatcctatgctgtgtctgcagctaaccatgtaaaggctaaa
aaacaaaatcgaccaggtgcccttgctaaaatttcacctcttcagtcgccctgctcctcc
cctctccaagggactcctgccagcagccctatcagcaaaatttctgccttgcaatttcca
gaatctgcggagacaactgccaaacatggtccaagttctcacaggactttaacctatact
caaagtgcccctgacctgtctcctcagatcttggatccacctgttatatgtagcagctgt
ggcagaccatattctcaagcgactcctgctgacgggcccctggagaaaagtggcgaggcc
actcagacatccagccgaacagatgacactgcccaagttacctctgattatgaaaccaac
aacaacagcgacagcagtgacattctacagaatgaagatgaggctgagtgttccagagaa
tctctgaggaagacgctggcttgtggcacctacggtcctgaagccatgatatacctggat
aaaccaattcttgctcctgaacctctcatcatggataacctggactcaattatggaacag
ctaaatacttggaattttcctatttttgacttggtggaaaatatagggaaaaaatgtggc
cgtattcttagtcaggtctcctacagactttttgaagacatgggcctcttcgaagctttt
aaaattccagttagagaatttatgaattattttcatgcattggagattggatacagggat
attccttatcataacagaatccatgccactgacgtcttacatgctgtttggtatcttact
acacagcctattccaggcctgtccactgtggttaatgatcccggatcagcaagtgattca
gattctgacagtggatttacacatggacacataggatatgtgttttcaaaactgtataat
gcagcggatgataaatacggatgtctttctggaaacatccctgccttggagttgatggcg
ctgtacgtggctgcagccatgcatgactatgaccacccagggaggaccaatgccttcctg
gttgctactagtgctcctcaggcggtgctatacaatgatcgttccgttttggagaaccat
catgcagctgcagcatggaatcttttcatgtcccggccagagtacaacttcttaagtaac
cttgaccatgtggaatttaagcatttccgttttcttgtcattgaagcaattttggccact
gacctgaagaaacactttgacttcgtaaccaaatttaatgccaaggtgaatgatgatgtt
ggaatagattggaccaatgaaaatgatcgtctcctggtttgtcaaatgtgtataaagcta
gctgatattaatggaccagctaagtgtaaagaacttcatcttcagtggacagagggtatt
gtcaatgaattttatgaacagggtgatgaagaggccagccttgggctacccatcagccct
ttcatggaccgctctgctcctcagctggccaatctgcaggaatccttcatctctcacatt
gtggggccgctgtgcaactcctatgactcagcaggactcatgccaggaaagtgggttgaa
gacagcgatgaatcgggagatactgatgaccctgaagaggaagaggaagctgcagtggtg
aatgaagaagaaacctgtgaaaatgatgaatctcccaaaaagaaaacttttaagaggagg
aaaatctactgccaaataactcagcacctcctacagaaccataagatgtggaagaaagtc
attgaagaggagcagcgattgaccggcattggaaatccaggcctggaccagtctgctcag
cagcacacctcagagcaaatccaggccatcgaggaagaagacgaagagaaggggaaacca
agagcagaggaaaccccggccccaaagccaaaccagtga
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