Cavia porcellus (domestic guinea pig): 100726234
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Entry
100726234 CDS
T07777
Symbol
Atp2a1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc04020
Calcium signaling pathway
cpoc04022
cGMP-PKG signaling pathway
cpoc04024
cAMP signaling pathway
cpoc04148
Efferocytosis
cpoc04260
Cardiac muscle contraction
cpoc04261
Adrenergic signaling in cardiomyocytes
cpoc04380
Osteoclast differentiation
cpoc04919
Thyroid hormone signaling pathway
cpoc04972
Pancreatic secretion
cpoc05010
Alzheimer disease
cpoc05017
Spinocerebellar ataxia
cpoc05022
Pathways of neurodegeneration - multiple diseases
cpoc05410
Hypertrophic cardiomyopathy
cpoc05412
Arrhythmogenic right ventricular cardiomyopathy
cpoc05414
Dilated cardiomyopathy
cpoc05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
100726234 (Atp2a1)
04024 cAMP signaling pathway
100726234 (Atp2a1)
04022 cGMP-PKG signaling pathway
100726234 (Atp2a1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100726234 (Atp2a1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100726234 (Atp2a1)
09153 Circulatory system
04260 Cardiac muscle contraction
100726234 (Atp2a1)
04261 Adrenergic signaling in cardiomyocytes
100726234 (Atp2a1)
09154 Digestive system
04972 Pancreatic secretion
100726234 (Atp2a1)
09158 Development and regeneration
04380 Osteoclast differentiation
100726234 (Atp2a1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100726234 (Atp2a1)
05017 Spinocerebellar ataxia
100726234 (Atp2a1)
05022 Pathways of neurodegeneration - multiple diseases
100726234 (Atp2a1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100726234 (Atp2a1)
05412 Arrhythmogenic right ventricular cardiomyopathy
100726234 (Atp2a1)
05414 Dilated cardiomyopathy
100726234 (Atp2a1)
05415 Diabetic cardiomyopathy
100726234 (Atp2a1)
Enzymes [BR:
cpoc01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
100726234 (Atp2a1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
100726234
NCBI-ProteinID:
XP_003477883
Ensembl:
ENSCPOG00000001991
UniProt:
H0UXI0
LinkDB
All DBs
Position
Unknown
AA seq
1001 aa
AA seq
DB search
MEAAHSKTTEECLAYFGVSETTGLTPDQVKRHLEKYGPNELPAEEGKSLWELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDMVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSIL
TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVNTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVDGDMCLLNEFSITGSTYAPEGEVLKNDKPVRAGQYDGLVELATICALC
NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSSRAVVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP
VKEKIMSVIKEWGTGRDTLRCLALATRDAPPKREEMILDDSSKFMEYETDLTFVGVVGML
DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFSESEEVVDRAYTGREFDD
LPLPEQREACRRACCFARVEPSHKSKIVEYLQSFDEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI
GGYVGAATVGAAAWWFLYADDGPHVTYHQLTHFMQCTEHNPEFGDMDCEIFEAPEPMTMA
LSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR
ALNLTQWLMVLKISLPVIGLDEILKFIARNYLEDPEDERRK
NT seq
3006 nt
NT seq
+upstream
nt +downstream
nt
atggaggctgcacactccaagaccacagaggaatgtttggcctattttggggtgagtgag
accacaggcctcaccccggaccaagttaagcgacatctggagaaatatggccccaatgag
ctccccgctgaggaagggaaatccctgtgggagttggtgatagagcagtttgaagacctc
ctggtgcggatccttctcctggccgcctgcatttcctttgtgctggcctggtttgaggaa
ggtgaagagaccatcaccgccttcgttgaaccctttgtcatcctcttgatcctcattgcc
aatgccatcgtgggagtctggcaggagcgtaatgcagagaacgccatcgaggcactgaag
gagtatgagcctgagatggggaaggtctaccgggctgaccgcaagtcagtgcaaaggatc
aaggctcgggacatggtccctggggacattgtggaggtggctgtgggggacaaagtccct
gcagacatccggatcctttccatcaaatccactaccctccgggttgaccagtccatcctg
acaggtgaatctgtgtctgtcatcaagcacactgaacctgtccctgatccccgagctgtc
aaccaggacaagaaaaacatgcttttctcgggcaccaacattgcagccggcaaagccttg
gggattgtggccaccactggtgtgaacactgagattgggaagatccgtgaccaaatggct
gccacagagcaggacaagacccctctgcagcagaagcttgatgagtttggggagcagctt
tctaaggtcatctccctcatctgtgtggctgtctggctcatcaacattggccacttcaac
gaccctgtccatgggggctcctggttccgcggtgctatctactactttaagatcgctgtg
gccctggctgtggctgcaatcccagaaggtcttcctgccgtcatcaccacctgtctggcc
ctgggcacccgccggatggcaaagaagaatgccattgtgaggagcttgccctccgtggag
accctgggctgcacgtctgtcatctgctctgacaagacaggcaccctcaccaccaaccag
atgtcggtgtgcaagatgtttatcattgacaaggtggatggggacatgtgcctgctgaat
gaattctccatcaccggctccacttatgctcctgagggagaggtcttgaagaatgataag
ccagtccgggcagggcagtatgatgggctggtggagctggccaccatttgtgccctgtgc
aatgactcctccttggacttcaatgaggccaaaggagtctatgagaaggtcggcgaggcc
accgagacagcgctcaccaccctggtggagaagatgaatgtgttcaacactgatgtgagg
agtctctcgaaggtggagagggccaacgcctgcaactcggtgatccggcagctgatgaag
aaggagttcaccttggagttctcccgagacagaaagtccatgtctgtctactgctcccct
gccaagtcttcccgggctgttgtgggcaacaagatgtttgtcaagggtgcccccgagggg
gtcatcgaccgctgtaactacgtgcgggtgggcaccactcgggtgccgttgacgggtcca
gtgaaggaaaagatcatgtcggtgatcaaagagtggggcactggccgggacaccctgcgc
tgcctggccctagccacccgagatgctccccccaagcgagaggagatgatcctggatgat
tcttccaagttcatggaatatgagacggacctgacattcgttggtgtggtgggcatgctg
gaccccccacgcaaggaggtcacaggctccatccagctgtgccgcgacgctgggatccgg
gtgatcatgatcactggagacaacaagggcacggccattgccatttgccgacgaattggc
atcttttcagagagtgaggaggtggttgaccgagcctacacaggccgagagttcgacgac
ctgcccctccccgagcagcgggaagcctgccgccgcgcttgctgcttcgcccgagtggag
ccctcacacaagtccaagatcgtggagtacctgcagtcctttgatgagatcacggccatg
acaggagatggtgtcaatgatgcccctgctctgaagaaggctgagattggcattgccatg
ggatctggcactgctgtggccaaaacagcctcagagatggtgttggccgatgacaacttc
tccacgatcgtggctgccgtggaggagggccgcgccatctacaacaacatgaagcagttc
atccgctacctcatctcctccaatgtgggcgaggtggtctgcatcttcctgacagctgcc
ttggggctgcctgaggccctgatcccagtgcagctactgtgggtgaacttggtgactgat
gggctcccagccacagcgctgggcttcaacccaccagacctggacatcatggaccgaccc
cctcggagccccaaggagcctctcatcagcggctggctcttcttccgctacatggccatt
gggggttacgtgggtgcagccaccgtgggagcagctgcctggtggttcttgtatgcagac
gatggccctcatgtcacctaccaccagctgacccactttatgcagtgcactgagcacaac
cctgagtttggggatatggactgtgagatttttgaggcccctgagcctatgaccatggcc
ctgtctgtgctggtcaccattgagatgtgcaatgctctgaacagcctgtctgaaaaccag
tccctgatgcggatgccgccctgggtaaacatctggctgctgggttccatctgcctatcc
atgtccctccatttcctcattctctacgttgaccccctgccgatgatcttcaagctccgg
gccctgaacctcacgcagtggctcatggtcctcaaaatctcactgcctgtcattgggctg
gatgaaatcctcaagttcattgcccggaactacctggaggatccagaagatgaaagaagg
aagtaa
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