Crassaminicella thermophila: FQB35_05260
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Entry
FQB35_05260 CDS
T06186
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
crs
Crassaminicella thermophila
Pathway
crs00860
Porphyrin metabolism
crs01100
Metabolic pathways
crs01110
Biosynthesis of secondary metabolites
crs01120
Microbial metabolism in diverse environments
crs01240
Biosynthesis of cofactors
Module
crs_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
crs00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
FQB35_05260 (cobA)
Enzymes [BR:
crs01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
FQB35_05260 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
FQB35_05260 (cobA)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
PrsW-protease
Motif
Other DBs
NCBI-ProteinID:
QEK11822
UniProt:
A0A5C0SD19
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All DBs
Position
1115575..1117092
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AA seq
505 aa
AA seq
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MAIGKVFLIGAGPGDYKLITLKGIECIQKADVVLYDRLASPKLLKFAREDAELIYVGKAP
NNHAYTQEEINDVLVKKASEGKIVARLKGGDPFVFGRGGEEAQKLKENGISFEIVPGITS
AISVPAYSGIPVTHRNVSSSFHVITGNEDPTKEENVVDYKALAKIEGTLIFLMGVKNIGK
ICESLIKYGQSPDRPVAVIMKGTTIEQKMIKGTLSNIYDKVKENDFKNPSIIIIGEVVNL
SEVLGWYEKKALFGKKVLVTRTRQQASYLSRKLESLGAEAIEFPTIKIEKPKVFDEIDKA
IGKIEQYQWIIFTSVNGVVAFFERMKRLNFDIRLLYNAKLVAIGPATAKSLEDRGFTIEY
VPEEYRAEGIIEGLKDKIKEGDFVLLPRADIAREVLIKELQNIGAKVDNIHVYHTVVPKQ
DREKLLKILKDDGIDVITFTSSSTVKNFMEILGEENRFLLKDKKMAVIGPITEETAKDLG
LNVVIKAKEYTIDGLVTAIKNYYNQ
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
gtggcgataggaaaagtttttttaataggagcgggtcctggagactacaaattaataacg
ttaaagggaatagagtgtattcaaaaagcagatgttgtattatatgatagattggcaagc
cctaaattattaaaatttgctagagaagatgcagagttaatttatgtaggaaaagctcca
aataatcatgcatatacacaagaagaaattaatgatgtacttgttaaaaaagcttcagaa
ggaaaaatagttgctagattaaaaggaggagatccttttgtttttggaagaggtggagaa
gaagcacagaaactaaaggaaaatggaataagttttgaaattgttcctgggattacttca
gctatatcagtgccagcttattcaggtatacctgtaacccatagaaatgtaagttcttct
tttcatgttattactggcaatgaggatccaacaaaagaagaaaatgtagtagattataaa
gctctagcgaaaatagaaggaacccttatttttctaatgggtgtaaaaaatattgggaaa
atatgtgaaagtcttataaaatatggtcaaagtcctgatagaccagtagcagtaattatg
aaaggaactacaatagaacaaaaaatgattaaaggaactttatcaaatatttatgataaa
gtaaaagagaatgattttaagaatccatccattattattataggtgaggttgtaaattta
tctgaagtattagggtggtatgaaaaaaaagctttatttggaaagaaagtattagttaca
agaacaagacaacaagcaagttatttatcgagaaaacttgaaagtttaggggctgaagca
atagagtttccaacgataaaaatagaaaagccaaaagtttttgatgaaatagacaaagct
atagggaaaatagagcagtatcagtggatcatatttacgagtgtgaatggtgttgttgca
ttttttgagcgaatgaagcgattaaactttgatataagattattgtataatgctaagctt
gttgctataggacctgctactgctaagagtttagaagatagaggctttactattgaatat
gtgccagaagaatatagagcagaaggaattattgaagggctaaaagacaagataaaagag
ggagattttgtgcttttaccaagagcagatattgcaagagaagtgttaatcaaagagtta
caaaatataggtgcgaaagttgacaatatacatgtttatcatacagttgtgccgaaacaa
gatagagagaagctattaaaaatacttaaagatgatggaatagatgtgattacttttact
agttcttctacagtgaaaaatttcatggagattttaggagaagaaaacagatttttatta
aaagataaaaaaatggctgttattggaccgattacagaagaaactgcaaaagacttagga
ttaaatgttgttataaaggcaaaagagtataccattgatggtcttgttacagcaataaaa
aattattataatcagtaa
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