KEGG   Denitrificimonas caeni: O6P33_04420
Entry
O6P33_04420       CDS       T08709                                 
Symbol
dfrA1
Name
(GenBank) trimethoprim-resistant dihydrofolate reductase DfrA1
  KO
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
dce  Denitrificimonas caeni
Pathway
dce00670  One carbon pool by folate
dce00790  Folate biosynthesis
dce01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:dce00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    O6P33_04420 (dfrA1)
   00670 One carbon pool by folate
    O6P33_04420 (dfrA1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:dce01504]
    O6P33_04420 (dfrA1)
Enzymes [BR:dce01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     O6P33_04420 (dfrA1)
Antimicrobial resistance genes [BR:dce01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    O6P33_04420 (dfrA1)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: WBE26087
LinkDB
Position
924445..924918
AA seq 157 aa
MKLSLMVAISKNGVIGNGPDIPWSAKGEQLLFKAITYNQWLLVGRKTFESMGALPNRKYA
VVTRSSFTSDNENVLIFPSIKDALTNLKKITDHVIVSGGGEIYKSLIDQVDTLHISTIDI
EPEGDVYFPEIPSNFRPVFTQDFASNINYSYQIWQKG
NT seq 474 nt   +upstreamnt  +downstreamnt
gtgaaactatcactaatggtagctatatcgaagaatggagttatcgggaatggccctgat
attccatggagcgccaaaggtgaacagctcctgtttaaagctattacctataaccaatgg
ctgttggttggacgcaagacttttgaatcaatgggagcattacccaaccgaaagtatgcg
gtcgtaacacgttcaagttttacatctgacaatgagaacgtattgatctttccatcaatt
aaagatgctttaaccaacctaaagaaaataacggatcatgtcattgtttcaggtggtggg
gagatatacaaaagcctgatcgatcaagtagatacactacatatatctacaatagacatc
gagccggaaggtgatgtttactttcctgaaatccccagcaattttaggccagtttttacc
caagacttcgcctctaacataaattatagttaccaaatctggcaaaagggttaa

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