KEGG   DRUG: Epinephrine and lidocaine hydrochloride
Entry
D04052            Mixture   Drug                                   
Name
Epinephrine and lidocaine hydrochloride;
Adrenaline and lidocaine hydrochloride;
Xylocaine (TN)
Product
XYLOCAINE (Henry Schein), XYLOCAINE (Henry Schein), XYLOCAINE (Henry Schein), XYLOCAINE (Henry Schein), XYLOCAINE (Henry Schein)
  Generic
LIDOCAINE HCI (HF Acquisition Co LLC), LIDOCAINE HCI (HF Acquisition Co LLC), LIDOCAINE HCI AND EPINEPHRINE (HF Acquisition Co LLC), LIDOCAINE HCL AND EPINEPHRINE (B. Braun Medical), LIDOCAINE HCL AND EPINEPHRINE (HF Acquisition Co LLC), LIDOCAINE HCL AND EPINEPHRINE (HF Acquisition Co LLC), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (Cardinal Health 107), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (Henry Schein), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (Henry Schein), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (Henry Schein), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (Hospira)
Component
Adrenaline [DR:D00095], Lidcaine hydrochloride [DR:D02086]
Class
Metabolizing enzyme substrate
 DG01892  CYP1A2 substrate
 DG01633  CYP3A/CYP3A4 substrate
  DG02913  CYP3A4 substrate
Remark
Therapeutic category: 1214 2710
Product: D04052<JP/US>
Efficacy
Anesthetic (local)
Metabolism
Enzyme: CYP1A2 [HSA:1544], CYP3A4 [HSA:1576]
Interaction
Brite
USP drug classification [BR:br08302]
 Anesthetics
  Local Anesthetics
   Lidocaine/ Epinephrine
    D04052  Epinephrine and lidocaine hydrochloride
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   121  Local anesthetics
    1214  Xylidines
     D04052  Epinephrine and lidocaine hydrochloride
 2  Agents affecting individual organs
  27  Dental preparations
   271  Local anesthetics
    2710  Local anesthetics
     D04052  Epinephrine and lidocaine hydrochloride
Drug groups [BR:br08330]
 Metabolizing enzyme substrate
  DG01892  CYP1A2 substrate
   D04052  Epinephrine and lidocaine hydrochloride
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D04052  Epinephrine and lidocaine hydrochloride
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D04052
Other DBs
PubChem: 17398016
LinkDB

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