Dipodomys spectabilis (banner-tailed kangaroo rat): 122123339
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Entry
122123339 CDS
T07891
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp00562
Inositol phosphate metabolism
dsp01100
Metabolic pathways
dsp01521
EGFR tyrosine kinase inhibitor resistance
dsp01522
Endocrine resistance
dsp01524
Platinum drug resistance
dsp04012
ErbB signaling pathway
dsp04014
Ras signaling pathway
dsp04015
Rap1 signaling pathway
dsp04024
cAMP signaling pathway
dsp04062
Chemokine signaling pathway
dsp04066
HIF-1 signaling pathway
dsp04068
FoxO signaling pathway
dsp04070
Phosphatidylinositol signaling system
dsp04071
Sphingolipid signaling pathway
dsp04072
Phospholipase D signaling pathway
dsp04140
Autophagy - animal
dsp04150
mTOR signaling pathway
dsp04151
PI3K-Akt signaling pathway
dsp04152
AMPK signaling pathway
dsp04210
Apoptosis
dsp04211
Longevity regulating pathway
dsp04213
Longevity regulating pathway - multiple species
dsp04218
Cellular senescence
dsp04360
Axon guidance
dsp04370
VEGF signaling pathway
dsp04380
Osteoclast differentiation
dsp04510
Focal adhesion
dsp04550
Signaling pathways regulating pluripotency of stem cells
dsp04611
Platelet activation
dsp04613
Neutrophil extracellular trap formation
dsp04620
Toll-like receptor signaling pathway
dsp04625
C-type lectin receptor signaling pathway
dsp04630
JAK-STAT signaling pathway
dsp04650
Natural killer cell mediated cytotoxicity
dsp04660
T cell receptor signaling pathway
dsp04662
B cell receptor signaling pathway
dsp04664
Fc epsilon RI signaling pathway
dsp04666
Fc gamma R-mediated phagocytosis
dsp04668
TNF signaling pathway
dsp04670
Leukocyte transendothelial migration
dsp04722
Neurotrophin signaling pathway
dsp04725
Cholinergic synapse
dsp04750
Inflammatory mediator regulation of TRP channels
dsp04810
Regulation of actin cytoskeleton
dsp04910
Insulin signaling pathway
dsp04914
Progesterone-mediated oocyte maturation
dsp04915
Estrogen signaling pathway
dsp04917
Prolactin signaling pathway
dsp04919
Thyroid hormone signaling pathway
dsp04923
Regulation of lipolysis in adipocytes
dsp04926
Relaxin signaling pathway
dsp04929
GnRH secretion
dsp04930
Type II diabetes mellitus
dsp04931
Insulin resistance
dsp04932
Non-alcoholic fatty liver disease
dsp04933
AGE-RAGE signaling pathway in diabetic complications
dsp04935
Growth hormone synthesis, secretion and action
dsp04960
Aldosterone-regulated sodium reabsorption
dsp04973
Carbohydrate digestion and absorption
dsp05010
Alzheimer disease
dsp05017
Spinocerebellar ataxia
dsp05020
Prion disease
dsp05100
Bacterial invasion of epithelial cells
dsp05132
Salmonella infection
dsp05135
Yersinia infection
dsp05142
Chagas disease
dsp05146
Amoebiasis
dsp05160
Hepatitis C
dsp05161
Hepatitis B
dsp05162
Measles
dsp05163
Human cytomegalovirus infection
dsp05164
Influenza A
dsp05165
Human papillomavirus infection
dsp05166
Human T-cell leukemia virus 1 infection
dsp05167
Kaposi sarcoma-associated herpesvirus infection
dsp05168
Herpes simplex virus 1 infection
dsp05169
Epstein-Barr virus infection
dsp05170
Human immunodeficiency virus 1 infection
dsp05171
Coronavirus disease - COVID-19
dsp05200
Pathways in cancer
dsp05203
Viral carcinogenesis
dsp05205
Proteoglycans in cancer
dsp05206
MicroRNAs in cancer
dsp05207
Chemical carcinogenesis - receptor activation
dsp05208
Chemical carcinogenesis - reactive oxygen species
dsp05210
Colorectal cancer
dsp05211
Renal cell carcinoma
dsp05212
Pancreatic cancer
dsp05213
Endometrial cancer
dsp05214
Glioma
dsp05215
Prostate cancer
dsp05218
Melanoma
dsp05220
Chronic myeloid leukemia
dsp05221
Acute myeloid leukemia
dsp05222
Small cell lung cancer
dsp05223
Non-small cell lung cancer
dsp05224
Breast cancer
dsp05225
Hepatocellular carcinoma
dsp05226
Gastric cancer
dsp05230
Central carbon metabolism in cancer
dsp05231
Choline metabolism in cancer
dsp05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
dsp05415
Diabetic cardiomyopathy
dsp05417
Lipid and atherosclerosis
dsp05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
122123339
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
122123339
04014 Ras signaling pathway
122123339
04015 Rap1 signaling pathway
122123339
04370 VEGF signaling pathway
122123339
04630 JAK-STAT signaling pathway
122123339
04668 TNF signaling pathway
122123339
04066 HIF-1 signaling pathway
122123339
04068 FoxO signaling pathway
122123339
04070 Phosphatidylinositol signaling system
122123339
04072 Phospholipase D signaling pathway
122123339
04071 Sphingolipid signaling pathway
122123339
04024 cAMP signaling pathway
122123339
04151 PI3K-Akt signaling pathway
122123339
04152 AMPK signaling pathway
122123339
04150 mTOR signaling pathway
122123339
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
122123339
09143 Cell growth and death
04210 Apoptosis
122123339
04218 Cellular senescence
122123339
09144 Cellular community - eukaryotes
04510 Focal adhesion
122123339
04550 Signaling pathways regulating pluripotency of stem cells
122123339
09142 Cell motility
04810 Regulation of actin cytoskeleton
122123339
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
122123339
04613 Neutrophil extracellular trap formation
122123339
04620 Toll-like receptor signaling pathway
122123339
04625 C-type lectin receptor signaling pathway
122123339
04650 Natural killer cell mediated cytotoxicity
122123339
04660 T cell receptor signaling pathway
122123339
04662 B cell receptor signaling pathway
122123339
04664 Fc epsilon RI signaling pathway
122123339
04666 Fc gamma R-mediated phagocytosis
122123339
04670 Leukocyte transendothelial migration
122123339
04062 Chemokine signaling pathway
122123339
09152 Endocrine system
04910 Insulin signaling pathway
122123339
04923 Regulation of lipolysis in adipocytes
122123339
04929 GnRH secretion
122123339
04915 Estrogen signaling pathway
122123339
04914 Progesterone-mediated oocyte maturation
122123339
04917 Prolactin signaling pathway
122123339
04926 Relaxin signaling pathway
122123339
04935 Growth hormone synthesis, secretion and action
122123339
04919 Thyroid hormone signaling pathway
122123339
09154 Digestive system
04973 Carbohydrate digestion and absorption
122123339
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
122123339
09156 Nervous system
04725 Cholinergic synapse
122123339
04722 Neurotrophin signaling pathway
122123339
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
122123339
09158 Development and regeneration
04360 Axon guidance
122123339
04380 Osteoclast differentiation
122123339
09149 Aging
04211 Longevity regulating pathway
122123339
04213 Longevity regulating pathway - multiple species
122123339
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122123339
05206 MicroRNAs in cancer
122123339
05205 Proteoglycans in cancer
122123339
05207 Chemical carcinogenesis - receptor activation
122123339
05208 Chemical carcinogenesis - reactive oxygen species
122123339
05203 Viral carcinogenesis
122123339
05230 Central carbon metabolism in cancer
122123339
05231 Choline metabolism in cancer
122123339
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
122123339
09162 Cancer: specific types
05210 Colorectal cancer
122123339
05212 Pancreatic cancer
122123339
05225 Hepatocellular carcinoma
122123339
05226 Gastric cancer
122123339
05214 Glioma
122123339
05221 Acute myeloid leukemia
122123339
05220 Chronic myeloid leukemia
122123339
05218 Melanoma
122123339
05211 Renal cell carcinoma
122123339
05215 Prostate cancer
122123339
05213 Endometrial cancer
122123339
05224 Breast cancer
122123339
05222 Small cell lung cancer
122123339
05223 Non-small cell lung cancer
122123339
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
122123339
05170 Human immunodeficiency virus 1 infection
122123339
05161 Hepatitis B
122123339
05160 Hepatitis C
122123339
05171 Coronavirus disease - COVID-19
122123339
05164 Influenza A
122123339
05162 Measles
122123339
05168 Herpes simplex virus 1 infection
122123339
05163 Human cytomegalovirus infection
122123339
05167 Kaposi sarcoma-associated herpesvirus infection
122123339
05169 Epstein-Barr virus infection
122123339
05165 Human papillomavirus infection
122123339
09171 Infectious disease: bacterial
05132 Salmonella infection
122123339
05135 Yersinia infection
122123339
05100 Bacterial invasion of epithelial cells
122123339
09174 Infectious disease: parasitic
05146 Amoebiasis
122123339
05142 Chagas disease
122123339
09164 Neurodegenerative disease
05010 Alzheimer disease
122123339
05017 Spinocerebellar ataxia
122123339
05020 Prion disease
122123339
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122123339
05418 Fluid shear stress and atherosclerosis
122123339
05415 Diabetic cardiomyopathy
122123339
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
122123339
04932 Non-alcoholic fatty liver disease
122123339
04931 Insulin resistance
122123339
04933 AGE-RAGE signaling pathway in diabetic complications
122123339
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
122123339
01524 Platinum drug resistance
122123339
01522 Endocrine resistance
122123339
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dsp04131
]
122123339
Enzymes [BR:
dsp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
122123339
Membrane trafficking [BR:
dsp04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
122123339
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3_PI4_kinase
PI3Ka
PI3K_p85B
PI3K_rbd
PI3K_C2
Motif
Other DBs
NCBI-GeneID:
122123339
NCBI-ProteinID:
XP_042553622
LinkDB
All DBs
Position
Unknown
AA seq
1076 aa
AA seq
DB search
MKLTDARAAVICQPEGPLLATSCGPSQRVTGQDIPWVGCPMEFWTKEENQSVMVDFLLPT
GVYLNFPVSRNANLSTIKQVLWHHAQYEPFFHMLSDPEAYVFTCVNQTAEQQELEDEQRR
LCDVRPFLPVLRLVARECDHVKKLINSQISLLIGKGLHEFDSLRDPEVNDFRDKMCQFCE
EAAAHRQQLGWEAWLRYSFPLQLEPLARSLGAGTPRTPNQTLLVNVKFEGSEESFTFQVS
SKDKPLALMACALRKKAKMFPQCLVEQPEDYALRVNGRHEYLYGSYPLCQFQYICGCLHS
GWTPHLTMVHSSSILTMRDEQSNPTPQVQKPCTKPPPIPAKKPSLVSLWSLEKAFCIDLI
QGSKVNADERMKLVVQAGLFHGNELLCKTVCSSEVSMCSEPVWQQRLEFDINVCDLPRMT
RLCIMLYAVVEKTKKARSTKKKSKKADCPIAWANLMLFDYKNQLKTGECCLYMWPSVPGE
KGELLNPVGTVCSNPNTKSASTLLICLPEVAPHPVYYPALEKILELGHHGERAHATEEEQ
LQLREILERQGPGELYEHEKDLVWKLRHKVQEQFPEALARLLLVTKWNKHEDVAQMLYLL
RSWPELPVLSALELLDFSFPDCHVGSFAIRSLRKLTDDELSQYLLQLVQVLKYESYLDCE
LTKFLLDRALSNRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGCTHHMKMLMKQGEA
LSKLKALNDFVKVSSQKMTKPQTKELMHLCMRQDTYMEVLSHLQSPLDPSTLLEEVCVEQ
CTFMDSKMKPLWIMYSSEEAGYAGNMGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDL
RMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNNSNMAATAAFNKDALLNWLKSKNPGEAL
DRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRE
RVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPD
LSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWMAHNVSKDNRQ
NT seq
3231 nt
NT seq
+upstream
nt +downstream
nt
atgaagctcactgatgcccgagcagctgtaatctgccagccagaggggcctttgctggcc
acctcttgtggcccatcccagagagtgacagggcaggatattccctgggtgggctgccct
atggaattctggaccaaggaggagaatcagagcgtgatggtggacttcctgctgcccact
ggggtctacctgaatttcccggtgtcccgcaatgccaacctcagcaccatcaagcaggtg
ctgtggcaccatgcccagtacgagccattcttccacatgctcagcgaccctgaggcctat
gtgttcacctgcgtcaaccagacagctgagcagcaggagctggaggatgagcagcgtcgg
ctgtgtgatgtccggcccttcttgcctgtgctgcgtctggtggcccgggagtgtgaccat
gtgaagaagctcatcaactcgcagatcagtctcctcatcggcaaaggcctccatgagttt
gactccctgcgggacccagaagtgaatgacttccgagacaagatgtgccagttctgcgaa
gaggcggctgcacaccgccagcagctgggctgggaggcctggctgcggtacagcttcccc
ctgcagttggagcctttggccaggagcttgggggctggcaccccaaggacccccaaccag
accctgctggttaatgtcaagttcgaaggcagtgaggaaagcttcactttccaagtgtcc
agcaaagacaaacccctagcactgatggcctgtgccctccggaagaaagccaagatgttc
ccacagtgcctagtggagcagcctgaggactatgctctgcgggtgaatgggaggcatgag
tatctctatggcagctaccccctctgccagttccagtacatctgcggctgcctgcacagt
ggatggaccccccacctgaccatggtccattcctcctccatcctcaccatgcgggatgag
caaagcaaccccaccccccaggttcagaaaccatgcaccaagccgccccccattcctgca
aagaagccttccttggtgtcgctgtggtctctggagaaggcattctgcatcgatctgatc
cagggaagcaaagtgaatgcagacgagaggatgaagctggtggtgcaggccggactcttc
catggaaatgaattgttgtgcaagacagtgtgcagctcggaggtgagcatgtgctcggaa
cccgtgtggcagcagcggctggagtttgacatcaatgtctgtgacctgccccgcatgacc
cggctctgcatcatgctctacgctgtggtggagaagaccaagaaggctcgctccaccaag
aagaagtccaagaaggcggactgccccattgcctgggccaacctcatgctgtttgactat
aagaaccagctcaagactggagagtgctgcctctacatgtggccgtctgtcccaggtgag
aaaggagagctgctgaaccctgtgggcaccgtgtgcagcaaccccaacaccaagagtgcc
tctacactgcttatctgcttgcctgaggtggcccctcaccctgtttactaccctgccctg
gagaagatcctggagctgggccatcatggggagagggcacatgccactgaggaggagcaa
ctgcagctgcgagaaatcctggagcgccaggggcccggggaactatatgaacatgagaaa
gacttggtgtggaaactgaggcacaaagtccaggagcagttcccagaggcattggcccgc
ctgctgctggtcaccaagtggaacaaacatgaggatgtggcacagatgctctacctgcta
cgctcttggcctgagctgcccgtcctgagcgccctggagctgctggacttcagcttccct
gactgccacgtgggctcctttgccatcaggtccctacggaaactcacggatgacgagctt
tcccagtacctgctgcagctggtacaagtgctcaagtatgagtcctacctagactgcgaa
ctcaccaaattcctgctagaccgggccctgtccaaccgcaagatcggccacttcctcttc
tggcaccttcgctctgagatgcatgtgccatcggtggccctgcgctttggcctcatcttg
gaggcctactgcaggggctgcacccaccacatgaagatgctgatgaagcagggggaagca
ctgagcaagctgaaggcgctcaatgactttgtgaaggtgagctcccagaagatgaccaaa
ccccagaccaaggaactaatgcacctgtgcatgcgccaggacacctacatggaggtcctc
tcccatctgcagtccccgctggacccaagcaccctgctggaggaagtctgtgtggagcag
tgtaccttcatggactccaagatgaagcccctgtggatcatgtacagcagtgaggaggcg
ggctatgcaggcaacatgggtatcatctttaagaatggggatgacctccggcaggacatg
ctaaccctgcagatgatccagctcatggacatcctgtggaagcaggagggcctggacctg
aggatgactccctatggctgcctccccactggcgaccgtactggcctcatcgaggtagtg
ctccactcggacaccatagccaacatccagctgaacaacagcaatatggcagccacagct
gccttcaacaaggatgccctgctcaactggctcaagtccaagaaccctggggaggccctg
gatagagccatcgaggagttcaccctctcctgtgctggctactgcgtggccacctatgtg
ttgggcattggtgaccggcacagtgacaacatcatgatccgggagagtgggcagttgttc
catattgactttggccactttctggggaatttcaagactaagtttggaatcaaccgcgag
cgagtcccattcatcctcacctatgattttgtccacgtgattcagcaggggaagacaaac
aacagtgagaaatttgaaaggttccggggctactgtgaaagagcgtacaccatcctgcgg
cgccacgggctcctcttcctccacctctttgctctgatgcgggcagcaggcctgcctgat
ctcagctgctccaaagacatccagtatctcaaggactctctggccctgggaaaaacagag
gaagaggccctaaagcacttccgggtgaagttcaatgaagcgctgcgtgagagctggaag
accaaagtgaactggatggcgcacaatgtgtccaaagataacaggcaatag
DBGET
integrated database retrieval system