Escherichia coli K-12 MG1655: b0381 Help Entry b0381             CDS       T00007                                  Symbol ddlA Name (RefSeq) D-alanine--D-alanine ligase A   KO K01921   D-alanine-D-alanine ligase [EC:6.3.2.4] Organism eco  Escherichia coli K-12 MG1655 Pathway eco00470   D-Amino acid metabolism eco00550   Peptidoglycan biosynthesis eco01100   Metabolic pathways eco01502   Vancomycin resistance Brite KEGG Orthology (KO) [BR:eco00001]  09100 Metabolism   09106 Metabolism of other amino acids    00470 D-Amino acid metabolism     b0381 (ddlA)   09107 Glycan biosynthesis and metabolism    00550 Peptidoglycan biosynthesis     b0381 (ddlA)  09160 Human Diseases   09175 Drug resistance: antimicrobial    01502 Vancomycin resistance     b0381 (ddlA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01011 Peptidoglycan biosynthesis and degradation proteins [BR:eco01011]     b0381 (ddlA) Enzymes [BR:eco01000]  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.2  Acid-D-amino-acid ligases (peptide synthases)     6.3.2.4  D-alanine---D-alanine ligase      b0381 (ddlA) Peptidoglycan biosynthesis and degradation proteins [BR:eco01011]  Precursor biosynthesis   Amino acid ligase    b0381 (ddlA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp ATPgrasp_ST ATP-grasp_4 RimK GARS_A Motif Other DBs NCBI-GeneID:  945313 NCBI-ProteinID:  NP_414915 Pasteur:  ddlA RegulonDB:  ECK120000207 ECOCYC:  EG10213 ASAP:  ABE-0001309 UniProt:  P0A6J8 LinkDB All DBs Position complement(399829..400923) Genome browser AA seq 364 aa AA seqDB search MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGIDKQGQWHVSDASNYLLN ADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVIFPIVHGTLGEDGSLQGML RVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFITLTRANRHNISFAEVESKLGL PLFVKPANQGSSVGVSKVTSEEQYAIAVDLAFEFDHKVIVEQGIKGREIECAVLGNDNPQ ASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAPEINDKIRAIAVQAYQTLGCAGMAR VDVFLTPENEVVINEINTLPGFTNISMYPKLWQASGLGYTDLITRLIELALERHAADNAL KTTM NT seq 1095 nt NT seq  +upstreamnt  +downstreamnt atggaaaaactgcgggtaggaatcgtttttggtggtaaatcagcggaacatgaagtgtct ctgcaatcggcaaaaaacattgtcgatgccattgataaaagtcgcttcgacgttgtgctg ctgggcattgataaacaagggcaatggcacgtcagcgatgccagcaattatctgctaaat gcagacgatcctgcccatattgcgttgcgcccttcggcgaccagccttgcgcaggtgcca ggtaaacatgagcatcagcttatcgacgcgcaaaacggtcagccgttgccgacggtggat gtcattttcccgattgtccacggtacgctgggcgaagatggttccttgcagggaatgctg cgggtcgccaatttaccgtttgtaggttctgatgttctggcttcagcagcctgtatggac aaagatgtcaccaaacgtctgctacgcgatgccgggctgaacattgcgccatttattacc ctgacgcgcgccaatcgtcacaacattagttttgccgaagtggagtctaaactggggtta ccactgtttgtaaaaccggctaatcagggctcttctgttggtgtcagcaaagtaaccagt gaagaacagtacgcaattgccgtcgatctggcgttcgagttcgatcataaagtgatcgtt gagcaagggatcaaaggtcgtgagatcgaatgcgcagttctgggcaacgacaatccgcaa gccagcacctgtggagagatcgtactcaccagcgatttctatgcctacgacaccaagtac attgacgaagatggcgcgaaagtggtagttccggcagccattgcgccagaaatcaacgat aagatccgggcgattgccgttcaggcttatcaaacgttgggatgcgcaggcatggcgcgt gtagacgtgtttttaaccccagagaacgaagtggtgatcaacgagatcaacaccctgcct ggcttcactaatatcagtatgtatccgaagctgtggcaagccagcggtctgggttacacc gatctgatcacacgtttgattgaactggcgctggagcgtcacgctgcggataacgcattg aaaaccacaatgtaa

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