Enterococcus faecium ATCC 8459 = NRRL B-2354: M7W_400
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Entry
M7W_400 CDS
T02454
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
efm
Enterococcus faecium ATCC 8459 = NRRL B-2354
Pathway
efm00470
D-Amino acid metabolism
efm00550
Peptidoglycan biosynthesis
efm01100
Metabolic pathways
efm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
efm00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
M7W_400
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
M7W_400
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
M7W_400
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
efm01011
]
M7W_400
Enzymes [BR:
efm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
M7W_400
Peptidoglycan biosynthesis and degradation proteins [BR:
efm01011
]
Precursor biosynthesis
Amino acid ligase
M7W_400
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATP-grasp_4
CPSase_L_D2
ATP-grasp_3
RimK
Motif
Other DBs
NCBI-ProteinID:
AGE29047
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All DBs
Position
174323..175399
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AA seq
358 aa
AA seq
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MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEGQWVKGPLLTEKPASKD
VLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNGEDGTIQGFLETLNMPYVG
AGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKENPKKVFDQCEGSLLYPMFVKP
ANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGIEAREIEVAVLGNEDVRTTLPGE
VVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQEYAKLAYTMLGGSGLSRCDFFLTN
KNELFLNELNSMPGFTEFSMYPLLWENMGLKYGDLIEELIQLGMNRYHQRQSFFEKNE
NT seq
1077 nt
NT seq
+upstream
nt +downstream
nt
ttgaagattactttactatatggcggacgcagcgcagagcatgaagtttccattctttcc
gcattttcagttttaaatgccatttattataattattaccaagttcaactcgtatttatt
acaaaagaaggacaatgggtcaaaggtccattactaacagaaaaacctgctagcaaagat
gtcttgcatctttcatgggacccaagtggacagacagaggaaggctttacaggaaaagtg
atcaatccgggagaaatcaaagaagaaggagccatcgtttttccagttttacacgggcca
aacggggaagatggaacgatccaaggcttcttagagacattgaatatgccttatgtcggc
gcaggcgtattgaccagtgcatgtgccatggataaaatcatgaccaagtatattttacaa
gctgctggtgtgccgcaagttccttatgtaccagtacttaagaatcaatggaaagaaaat
cctaaaaaagtatttgatcaatgtgaaggttctttgctttatccgatgtttgtcaaacct
gcgaatatgggttctagtgtcggcattacaaaggcagaaaaccgagaagagctgcaaaat
gctttagcaacagcctatcagtatgattctcgagcaatcgttgaacaaggaattgaagcg
cgcgaaatcgaagttgctgtattaggaaatgaagatgttcggacgactttgcctggcgaa
gtcgtaaaagacgtagcattctatgattatgaagccaaatatatcaataataaaatcgaa
atgcagattccagccgaagtgccggaagaagtttatcaaaaagcgcaagagtacgcgaag
ttagcttacacgatgttaggtggaagcggattgagccggtgcgatttctttttgacaaat
aaaaatgaattattcctgaatgaattaaactctatgccaggatttacggagttcagtatg
tacccactcttatgggaaaatatgggcttgaaatacggtgatttgattgaagaactgatt
caattaggaatgaatcgataccatcagcgtcaatctttttttgaaaaaaatgaataa
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