KEGG   Eptesicus fuscus (big brown bat): 103289468
Entry
103289468         CDS       T09083                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus04010  MAPK signaling pathway
efus04020  Calcium signaling pathway
efus04022  cGMP-PKG signaling pathway
efus04114  Oocyte meiosis
efus04218  Cellular senescence
efus04310  Wnt signaling pathway
efus04360  Axon guidance
efus04370  VEGF signaling pathway
efus04380  Osteoclast differentiation
efus04625  C-type lectin receptor signaling pathway
efus04650  Natural killer cell mediated cytotoxicity
efus04658  Th1 and Th2 cell differentiation
efus04659  Th17 cell differentiation
efus04660  T cell receptor signaling pathway
efus04662  B cell receptor signaling pathway
efus04720  Long-term potentiation
efus04724  Glutamatergic synapse
efus04728  Dopaminergic synapse
efus04921  Oxytocin signaling pathway
efus04922  Glucagon signaling pathway
efus04924  Renin secretion
efus05010  Alzheimer disease
efus05014  Amyotrophic lateral sclerosis
efus05020  Prion disease
efus05022  Pathways of neurodegeneration - multiple diseases
efus05031  Amphetamine addiction
efus05152  Tuberculosis
efus05163  Human cytomegalovirus infection
efus05166  Human T-cell leukemia virus 1 infection
efus05167  Kaposi sarcoma-associated herpesvirus infection
efus05170  Human immunodeficiency virus 1 infection
efus05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
efus05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103289468 (PPP3CB)
   04310 Wnt signaling pathway
    103289468 (PPP3CB)
   04370 VEGF signaling pathway
    103289468 (PPP3CB)
   04020 Calcium signaling pathway
    103289468 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    103289468 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    103289468 (PPP3CB)
   04218 Cellular senescence
    103289468 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    103289468 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    103289468 (PPP3CB)
   04660 T cell receptor signaling pathway
    103289468 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    103289468 (PPP3CB)
   04659 Th17 cell differentiation
    103289468 (PPP3CB)
   04662 B cell receptor signaling pathway
    103289468 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    103289468 (PPP3CB)
   04921 Oxytocin signaling pathway
    103289468 (PPP3CB)
   04924 Renin secretion
    103289468 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    103289468 (PPP3CB)
   04728 Dopaminergic synapse
    103289468 (PPP3CB)
   04720 Long-term potentiation
    103289468 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    103289468 (PPP3CB)
   04380 Osteoclast differentiation
    103289468 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103289468 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103289468 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    103289468 (PPP3CB)
   05163 Human cytomegalovirus infection
    103289468 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103289468 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    103289468 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103289468 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    103289468 (PPP3CB)
   05020 Prion disease
    103289468 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    103289468 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    103289468 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103289468 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:efus01009]
    103289468 (PPP3CB)
Enzymes [BR:efus01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     103289468 (PPP3CB)
Protein phosphatases and associated proteins [BR:efus01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     103289468 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 103289468
NCBI-ProteinID: XP_008143601
LinkDB
Position
17:16583457..16639192
AA seq 525 aa
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDMDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVF
SVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSF
EEAKGLDRINERMPPRKDAVQPDGFNSLNTAHATENHGTGNHSAQ
NT seq 1578 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggccgcaccgcccccgcccccgcccccgccgccccct
cccggggctgaccgcgtcgtcaaagctgttcctttccctccaacacatcgcttgacatct
gaagaagtatttgatatggatgggatacctagggttgatgttctgaagaaccacttagta
aaagaaggtcgggtagatgaagaaattgcacttagaattatcaatgagggtgctgccatc
cttcggagagagaaaaccatgatagaagtagaggctccaattacagtgtgtggtgacatc
catggccaattttttgatctgatgaaactttttgaagtaggaggatcacctgctaataca
cgatacctttttcttggtgattatgtggacagaggttatttcagtatagagtgtgtctta
tatttatgggtcctgaagatactatacccaagcacattatttcttctgagaggcaatcat
gaatgcagacaccttactgaatattttacctttaagcaggaatgtaaaattaaatattca
gaaagagtctatgaagcttgtatggaagcttttgatagtctgcctcttgctgcactttta
aaccaacaatttctttgtgttcatggtggactttcaccagaaatccacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgtta
tggtccgatccttctgaagattttggaaatgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtatgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacaatttaactgttctccacatccttactggttgcccaattttatggatgtcttcaca
tggtctttaccatttgttggagaaaaagtgacagaaatgttggtaaatgttctgagtatt
tgctctgatgatgaactgatgactgaaggtgaagaccagtttgatgtaggttcagctgcc
gctcggaaagaaatcataagaaacaaaattcgagcaattggcaagatggcaagagtcttc
tctgttctcagggaggagagtgaaagtgtgctgacactcaagggtctgactcccacagga
atgttgcctagtggagtgttggctggaggacggcagaccctgcaaagtgccacagttgag
gctattgaggctgaaaaagcaatacgaggattctctccaccacatagaatctgcagtttt
gaagaggcaaagggtttggataggatcaatgagagaatgccaccccggaaagatgctgta
caaccagatggtttcaattctctgaacaccgcacatgccactgagaaccacgggactggc
aaccatagtgcccagtga

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