Eumetopias jubatus (Steller sea lion): 114208347 Help Entry 114208347         CDS       T07240                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism eju  Eumetopias jubatus (Steller sea lion) Pathway eju01521   EGFR tyrosine kinase inhibitor resistance eju04151   PI3K-Akt signaling pathway eju04217   Necroptosis eju04380   Osteoclast differentiation eju04550   Signaling pathways regulating pluripotency of stem cells eju04620   Toll-like receptor signaling pathway eju04621   NOD-like receptor signaling pathway eju04630   JAK-STAT signaling pathway eju04658   Th1 and Th2 cell differentiation eju04659   Th17 cell differentiation eju05140   Leishmaniasis eju05145   Toxoplasmosis eju05152   Tuberculosis eju05160   Hepatitis C eju05161   Hepatitis B eju05162   Measles eju05163   Human cytomegalovirus infection eju05164   Influenza A eju05165   Human papillomavirus infection eju05166   Human T-cell leukemia virus 1 infection eju05167   Kaposi sarcoma-associated herpesvirus infection eju05168   Herpes simplex virus 1 infection eju05169   Epstein-Barr virus infection eju05171   Coronavirus disease - COVID-19 eju05200   Pathways in cancer eju05203   Viral carcinogenesis eju05212   Pancreatic cancer eju05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:eju00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     114208347 (JAK1)    04151 PI3K-Akt signaling pathway     114208347 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     114208347 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     114208347 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     114208347 (JAK1)    04621 NOD-like receptor signaling pathway     114208347 (JAK1)    04658 Th1 and Th2 cell differentiation     114208347 (JAK1)    04659 Th17 cell differentiation     114208347 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     114208347 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     114208347 (JAK1)    05203 Viral carcinogenesis     114208347 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     114208347 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     114208347 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     114208347 (JAK1)    05161 Hepatitis B     114208347 (JAK1)    05160 Hepatitis C     114208347 (JAK1)    05171 Coronavirus disease - COVID-19     114208347 (JAK1)    05164 Influenza A     114208347 (JAK1)    05162 Measles     114208347 (JAK1)    05168 Herpes simplex virus 1 infection     114208347 (JAK1)    05163 Human cytomegalovirus infection     114208347 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     114208347 (JAK1)    05169 Epstein-Barr virus infection     114208347 (JAK1)    05165 Human papillomavirus infection     114208347 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     114208347 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     114208347 (JAK1)    05140 Leishmaniasis     114208347 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     114208347 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:eju01001]     114208347 (JAK1) Enzymes [BR:eju01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      114208347 (JAK1) Protein kinases [BR:eju01001]  Non-receptor tyrosine kinases   JAK family [OT]    114208347 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  114208347 NCBI-ProteinID:  XP_027958215 LinkDB All DBs Position Unknown AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLADREPLRLGNGEYTAEEL CIRAAQECRISPLCHNLFALYDENTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFHPNDSGNVLYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGT LVDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD YSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPRHCPDEVYQLMRKCWEFQPSNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagaccgaggtgaatctggaggcccctgagccaggggtggaagtgctcttc tatcttgctgatagggagcccctccgactgggcaacggagagtacacggcggaggagctg tgcatcagggccgcacaggaatgccgtatctctcctctgtgtcacaacctctttgccctg tatgatgagaacaccaagctctggtatgccccgaatcgcaccatcactgttgatgacaag acatcgctccggctccactaccggatgaggttttatttcaccaactggcacgggaccaat gataatgagcagtctgtatggcgacattctccaaagaagcagaaaaatggctatgagaaa aaaaaagtcccagatgcaacccctctccttgacgccagctctctggaatatctgtttgct cagggacaatatgatttggtcaaatgcctggctcccattcgagaccccaagaccgagcag gatgggcacgatatcgagaacgagtgtctgggaatggctgtcctggccatctcccactac gccatgatgaagaagatgcagttgccagaactgcccaaggacatcagctacaagcgatat attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataacgttttcaaggatttcctgaaggaatttaacaacaagactatttgtgacagcagc gtatctactcatgacctaaaggtgaaatacctagccaccttggaaactttgacaaaacat tatggcgctgaaatatttgagacttccatgttactgatttcatcagaaaatgagatgaat tggtttcatccgaatgacagtggaaatgttctctactatgaagtgatggtaactggaaat cttggaatccagtggagacagaaaccaaatgttgttcctgttgaaaaggaaaaaaacaaa ctgaaacggaaaaaactggaaaataaacacaagaaggatgaggagaaaaacaaaatccgg gaagaatggaacaatttttcttacttccctgaaatcacccacattgtaataaaggagtct gtggtcagcatcaataagcaggacaacaaaaaaatggaactgaagctctcgtcccacgaa gaggccttatcctttgtgtcgctggtcgacggctacttccggctcacagcagatgcccat cattacctctgcaccgatgtggctcccccactgatcgtccacaacatacagaatggttgt cacggtccaatctgcacagaatatgccatcaataagttgcggcaagaaggaagcgaggag gggatgtatgtgctgaggtggagctgtaccgactttgacaatatcctcatgactgtcacc tgctttgaaaaatctgaggtgctgggtggccaaaaacagttcaagaactttcagatcgag gtgcagaagggccgctatagcctgcacggctcagaccgcagcttccccagcctgggggac ctgatgagccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgctgaag cgctgctgccagcccaagccccgagagatctccaatctgctggtggctactaagaaagcc caggagtggcagcctgtctaccctatgagccagctgagttttgaccggatcctcaagaaa gatattgtgcaaggcgagcaccttgggagaggcacacggacacacatctactccggtacc ctggtggattacaaggatgacgaaggaacttccgaagagaagagaataaaagtgatcctc aaagtcttagaccccagccacagggacatttctctggccttctttgaagcagccagcatg atgaggcaggtctcccacaaacacatcgtgtacctctatggcgtctgtgtccgagacgtg gagaatatcatggtggaggagtttgtggagggtgggcccctggatctcttcatgcaccgg aaaagcgatgtcctcaccacaccatggaagttcaaagttgccaaacagctggccagcgcc ctgagttatttggaggataaagacctggtccacggaaacgtgtgcacaaaaaaccttctc ctggcccgtgagggcattgacagcgagtgcggcccgttcatcaagctcagtgaccctggc atccccatcaccgtgctgtccaggcaagagtgcatagaacgaatcccatggattgctccc gagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggaacc acactttgggagatctgctacaatggcgagatccctctgaaagacaagaccctgattgag aaagagagattctacgaaagccggtgccggccagtgacaccgtcttgcaaggagctggct gaccttatgacccgctgcatgaactatgaccccaaccagagacccttcttccgagccatc atgagagacatcaataaactggaagagcagaatccagacattgtttccgaaagaaagccg gcaaccgaagtagaccccacacattttgaaaagcgattcttgaagaggatccgtgacttg ggagagggccactttgggaaggttgagctctgcaggtatgaccctgagggggacaatacc ggggagcaggtggcggtcaaatccctgaagcccgagagtggaggcaaccacatagctgac ctgaagaaggaaattgaaatcctaaggaacctctatcatgagaacattgtgaagtacaaa ggcatctgtacagaagatggaggaaatggtattaagctcatcatggaatttctgccttca ggaagtcttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcaatta aaatatgccgttcagatttgtaaggggatggactatttgggttctcggcagtacgttcac cgggacttggcagcaaggaatgtcctcgttgagagtgagcaccaagtgaaaattggagac tttggtttgaccaaagcaattgaaactgacaaggagtactacacagtcaaggatgatcgg gacagccctgtgttttggtatgctcccgaatgtttaattcagtgtaaattttatatcgcc tctgacgtctggtcgtttggagtgactctgcatgagctgcttacttactgtgactcagat tacagccccatggcgttgttcctgaaaatgataggcccaactcatggccaaatgacagtc acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacgtcactgtcca gatgaggtttatcaacttatgagaaaatgctgggaattccaaccatccaatcggacaact tttcagaaccttattgaaggatttgaagcacttttaaaataa

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