Escherichia coli O44 H18 042 (EAEC): EC042_0413
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Entry
EC042_0413 CDS
T02067
Symbol
ddlA
Name
(GenBank) D-alanine:D-alanine ligase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
elo
Escherichia coli O44:H18 042 (EAEC)
Pathway
elo00470
D-Amino acid metabolism
elo00550
Peptidoglycan biosynthesis
elo01100
Metabolic pathways
elo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
elo00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
EC042_0413 (ddlA)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EC042_0413 (ddlA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EC042_0413 (ddlA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
elo01011
]
EC042_0413 (ddlA)
Enzymes [BR:
elo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
EC042_0413 (ddlA)
Peptidoglycan biosynthesis and degradation proteins [BR:
elo01011
]
Precursor biosynthesis
Amino acid ligase
EC042_0413 (ddlA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATPgrasp_ST
ATP-grasp_4
RimK
GARS_A
Motif
Other DBs
NCBI-ProteinID:
CBG33246
UniProt:
D3GU73
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All DBs
Position
complement(459791..460885)
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AA seq
364 aa
AA seq
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MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGIDKQGQWHVSDASNYLLN
ADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVIFPIVHGTLGEDGSLQGML
RVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFITLTRANRHNISFAEVESKLGL
PLFVKPANQGSSVGVSKVTSEEQYAIAVDLAFEFDHKVIVEQGIKGREIECAVLGNDNPQ
ASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAPEINDKIRAIAVQAYQTLGCAGMAR
VDVFLTPENEVVINEINTLPGFTNISMYPKLWQASGLGYTDLITRLIELALERHAADNAL
KTTM
NT seq
1095 nt
NT seq
+upstream
nt +downstream
nt
atggaaaaactgcgggtaggaatcgtttttggtggtaaatcagcggaacatgaagtgtct
ctgcaatcggcaaaaaacattgtcgatgccattgataaaagtcgcttcgacgttgtgctg
ctgggcattgataaacaagggcaatggcacgtcagcgatgccagcaattatctgctaaat
gcagacgatcctgcccatattgcattgcgcccttcggcgaccagtcttgcgcaggtgcct
ggtaaacatgaacatcagcttatcgacgcgcaaaacggtcagccgttgccgacggtggat
gtcattttcccgattgtccacggtacgctgggcgaagatggttctttgcagggaatgctg
cgggtcgccaatttaccgtttgtaggttctgatgttctggcttcagcggcctgtatggat
aaagatgtcaccaaacgtctgctgcgcgatgccgggctgaacattgcgccatttattacc
ctgacgcgcgctaatcgtcacaacatcagttttgccgaagtggagtctaaactggggtta
ccgctgtttgtaaaaccggctaatcagggctcttctgttggtgtcagcaaagtaaccagt
gaagaacagtacgcaattgccgtcgatctggcgttcgagttcgaccataaagtgatcgtt
gagcaagggatcaaaggtcgtgagatcgaatgcgcagttctgggcaacgacaatccgcaa
gccagcacctgtggcgagatcgtactcaccagcgatttctatgcctacgacaccaagtac
attgatgaagatggcgcgaaagtggtagttccggcagccattgcgccagaaatcaacgat
aagatccgggcgattgccgttcaggcttatcagacgttgggatgcgcaggcatggcgcgt
gtagacgtgtttttaaccccagagaacgaagtggtgatcaacgagatcaacacactgcct
ggcttcaccaacatcagtatgtatccgaagctgtggcaagccagcggtctgggttacacc
gacctgatcacccgtttgattgaactggcgctggagcgtcacgctgcggataacgcattg
aaaaccacaatgtaa
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