Escherichia coli UM146: UM146_23245
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Entry
UM146_23245 CDS
T02000
Symbol
ddl
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
elu
Escherichia coli UM146
Pathway
elu00470
D-Amino acid metabolism
elu00550
Peptidoglycan biosynthesis
elu01100
Metabolic pathways
elu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
elu00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
UM146_23245 (ddl)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
UM146_23245 (ddl)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
UM146_23245 (ddl)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
elu01011
]
UM146_23245 (ddl)
Enzymes [BR:
elu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
UM146_23245 (ddl)
Peptidoglycan biosynthesis and degradation proteins [BR:
elu01011
]
Precursor biosynthesis
Amino acid ligase
UM146_23245 (ddl)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp_4
ATP-grasp
ATPgrasp_YheCD
TTL
ATPgrasp_ST
GARS_A
Motif
Other DBs
NCBI-ProteinID:
ADN73970
LinkDB
All DBs
Position
4865429..4866349
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AA seq
306 aa
AA seq
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MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFI
ALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRA
EFEKGLNDKQLAEISSLGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIE
KWLSGPEFTIAILGEEILPSIRIQPAGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL
VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVR
ILELAD
NT seq
921 nt
NT seq
+upstream
nt +downstream
nt
atgactgataaaatcgcggtcctgttgggcgggacctccgctgagcgggaagtttctctg
aattctggcgcagcggtgttagccgggctgcgtgaaggcggtattgacgcgtatcctgtc
gacccgaaagaagtcgacgtgacgcaactgaagtcgatgggttttcagaaagtgtttatc
gcgctacacggtcgcggcggtgaagatggtacgctgcagggcatgctcgagctgatgggc
ttgccttataccggcagcggagtgatggcatctgcgctttcaatggataaactacgcagc
aaacttctgtggcagggtgccggtttaccggtcgcgccgtgggtagcgttaacccgcgca
gagtttgaaaaaggccttaacgataagcagttagcagaaatttcttctctgggtttgccg
gttatcgttaagccgagccgcgaaggttccagtgtgggaatgtcaaaagtagtagcagaa
aatgctctacaagatgcattaagattggcatttcagcacgatgaagaagtattgattgaa
aaatggctaagtgggccggagttcacgattgcgatactcggtgaagaaattttaccgtca
atacgtattcaaccggccggaaccttctatgattatgaggcgaagtatctctctgatgag
acacagtatttctgccccgcaggtctggaagcgtcacaagaggccaatttgcaggcatta
gtgctaaaagcatggacgacgttaggttgcaaaggatggggacgtattgacgttatgctg
gacagtgatggacagttttatctgctggaagccaatacctcaccgggtatgaccagccac
agtctggtgccgatggcggcacgtcaggcaggtatgagcttctcgcagttggtagtacga
attctggaactggcggactaa
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