Equus przewalskii (Przewalski's horse): 103561050 Help Entry 103561050         CDS       T04644                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism epz  Equus przewalskii (Przewalski's horse) Pathway epz00230   Purine metabolism epz01100   Metabolic pathways epz01522   Endocrine resistance epz04015   Rap1 signaling pathway epz04020   Calcium signaling pathway epz04022   cGMP-PKG signaling pathway epz04024   cAMP signaling pathway epz04062   Chemokine signaling pathway epz04072   Phospholipase D signaling pathway epz04114   Oocyte meiosis epz04211   Longevity regulating pathway epz04213   Longevity regulating pathway - multiple species epz04261   Adrenergic signaling in cardiomyocytes epz04270   Vascular smooth muscle contraction epz04371   Apelin signaling pathway epz04540   Gap junction epz04611   Platelet activation epz04713   Circadian entrainment epz04714   Thermogenesis epz04723   Retrograde endocannabinoid signaling epz04724   Glutamatergic synapse epz04725   Cholinergic synapse epz04727   GABAergic synapse epz04742   Taste transduction epz04750   Inflammatory mediator regulation of TRP channels epz04911   Insulin secretion epz04912   GnRH signaling pathway epz04913   Ovarian steroidogenesis epz04914   Progesterone-mediated oocyte maturation epz04915   Estrogen signaling pathway epz04916   Melanogenesis epz04918   Thyroid hormone synthesis epz04921   Oxytocin signaling pathway epz04923   Regulation of lipolysis in adipocytes epz04925   Aldosterone synthesis and secretion epz04926   Relaxin signaling pathway epz04927   Cortisol synthesis and secretion epz04928   Parathyroid hormone synthesis, secretion and action epz04934   Cushing syndrome epz04935   Growth hormone synthesis, secretion and action epz04970   Salivary secretion epz04971   Gastric acid secretion epz04972   Pancreatic secretion epz04976   Bile secretion epz05032   Morphine addiction epz05163   Human cytomegalovirus infection epz05166   Human T-cell leukemia virus 1 infection epz05200   Pathways in cancer epz05207   Chemical carcinogenesis - receptor activation epz05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:epz00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103561050 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103561050 (ADCY4)    04371 Apelin signaling pathway     103561050 (ADCY4)    04020 Calcium signaling pathway     103561050 (ADCY4)    04072 Phospholipase D signaling pathway     103561050 (ADCY4)    04024 cAMP signaling pathway     103561050 (ADCY4)    04022 cGMP-PKG signaling pathway     103561050 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103561050 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     103561050 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103561050 (ADCY4)    04062 Chemokine signaling pathway     103561050 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     103561050 (ADCY4)    04923 Regulation of lipolysis in adipocytes     103561050 (ADCY4)    04912 GnRH signaling pathway     103561050 (ADCY4)    04913 Ovarian steroidogenesis     103561050 (ADCY4)    04915 Estrogen signaling pathway     103561050 (ADCY4)    04914 Progesterone-mediated oocyte maturation     103561050 (ADCY4)    04921 Oxytocin signaling pathway     103561050 (ADCY4)    04926 Relaxin signaling pathway     103561050 (ADCY4)    04935 Growth hormone synthesis, secretion and action     103561050 (ADCY4)    04918 Thyroid hormone synthesis     103561050 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     103561050 (ADCY4)    04916 Melanogenesis     103561050 (ADCY4)    04925 Aldosterone synthesis and secretion     103561050 (ADCY4)    04927 Cortisol synthesis and secretion     103561050 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103561050 (ADCY4)    04270 Vascular smooth muscle contraction     103561050 (ADCY4)   09154 Digestive system    04970 Salivary secretion     103561050 (ADCY4)    04971 Gastric acid secretion     103561050 (ADCY4)    04972 Pancreatic secretion     103561050 (ADCY4)    04976 Bile secretion     103561050 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     103561050 (ADCY4)    04727 GABAergic synapse     103561050 (ADCY4)    04725 Cholinergic synapse     103561050 (ADCY4)    04723 Retrograde endocannabinoid signaling     103561050 (ADCY4)   09157 Sensory system    04742 Taste transduction     103561050 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     103561050 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     103561050 (ADCY4)    04213 Longevity regulating pathway - multiple species     103561050 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     103561050 (ADCY4)    04714 Thermogenesis     103561050 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103561050 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     103561050 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103561050 (ADCY4)    05163 Human cytomegalovirus infection     103561050 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     103561050 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103561050 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103561050 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103561050 (ADCY4) Enzymes [BR:epz01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103561050 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  103561050 NCBI-ProteinID:  XP_008533665 LinkDB All DBs Position Un AA seq 1077 aa AA seqDB search MARLFSPRPQPSEDLFYETYYSLSQQYPLLLMLLAIVLCALLALLAVAWASGRELASDTG FLTTVLCALGGFSLLLGLASREHRLQRWTRPLSGLVWAALLALGYSFLFTGGVVSAWDQV SFFLFVIFTVYAMLPLGMRDATAAGLASSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAQEMK AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG AYAVEDAAMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR YLESWGAAKPFAHLSHIESPVSTSTPLPEKALASFSPQWSLDRSRTPRGLDEELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFKYYTACTFLVFLSIFI VQMLVTNRPPALAITYSITFLLFLLLLFICFSEHLTRCVLKGPKVLHWLPALSGLVSTRP GLRVALGTATILLVFAMAITSLFFLPPASKCPFQAPNVSSMALNLSWELPGSLPLISIPY SMHCCVLGFLSCSLFLHMSFELKLLLLLLWLTASCSLFLHSHAWLSDCLIARLYLGPADS RPGVLKEPKMMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMV EFTVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGPPSAALG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagtccccggccgcagcccagcgaagacctcttctacgagacctac tacagcctgagccagcagtacccactgctgctaatgctgctggccatcgtgctctgcgcg ctcctggcgctgctcgcggtcgcctgggccagtggcagggagctggcctctgacacgggc ttcctgaccactgtgctgtgcgcgttgggcggcttctcgttgctgctgggcttggcttcc cgcgagcaccgactgcagcgctggacgcgtcccctgtccggcctcgtgtgggcagcgctg cttgcgctaggctacagcttcctgttcaccgggggcgtggtgagcgcctgggaccaggta tcctttttcctctttgtcatcttcacggtctatgccatgctgcccttgggcatgcgggac gccaccgccgcgggcctcgcctcctcactctcacatctgctggttcttgggctgtatctt gggcctcaacccgactctaggcccgcgctgctgcctcagctggcagcaaacgcggtattg ttcctgtgcgggaacgtggctggagcgtaccacaaggcgctgatggagcgcgccctgcgc gccacgttccgggaggcgctgagttccctgcactcgcgccggcggctggacaccgagaag aagcaccaggaacaccttctcttgtccatccttcctgcctacttggcccaagagatgaag gcagagatcatggcacggctgcaggctggacaggggtcacggccagagagcaccaacaac ttccatagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcacgaggctggccagtgagtgctcccctaaagagttggtgctcatgctcaacgag ctctttggcaagttcgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctg ggagactgttactactgtgtctccgggctgccactctcgctgccagaccacgccatcaac tgcgtgcgcatggggctggacatgtgccgggccatcaggaaacttcgggcagccactggt gtggacatcaacatgcgtgtgggtgtgcactcaggcagcgtgctctgcggagtcatcggg ctgcagaagtggcagtacgatgtctggtcgcatgacgtcacactggccaaccacatggag gccggtggcgtgccagggcgcgtacatatcacaggggctaccctggccctgctggcaggg gcttatgctgtggaggatgcagccatggaacaccgagacccgtaccttcgggagctaggg gagcctacctacctggtcatcgatccccgggctgaggaagaggatgagaagggcactgca ggagggttgctgtcctctcttgagggccccaagatgcgtccatcactgctgatgacccgc tacctggagtcctggggtgcagccaagccttttgcccacctgagccacatagagagccca gtgtccacctccactcctctcccggagaaggccctggcttccttcagcccccagtggagc ctggaccggagccgtaccccccggggactagatgaggaattggacaccggggatgccaag ttcttccaggtcattgaacagctcaactctcagaaacagtggaagcagtcgaaggacttc aacccactgacactgtacttccgagagaaggagatggagaaagagtatcgactctctgca ctccccgccttcaaatactacacagcctgcaccttcctggtttttctctccatcttcatc gtccagatgctggtgacaaacaggcccccagctctggccatcacctatagtatcaccttc ctcctcttcctcctcctcctcttcatctgtttctcagagcacctgacgaggtgtgtcttg aaaggccccaaggtgctacactggctgcctgcactgtctggcctggtgtccacacggccc ggactgcgagtcgccctgggcaccgccaccatccttctcgtcttcgccatggccattacc agcctgttcttcttaccgccagcatcgaagtgccctttccaggctcccaatgtgtcctcc atggctttgaacctctcctgggagctccctgggtccctgcctctcatcagcatcccatac tccatgcactgctgcgtgctgggtttcctctcctgctccctctttctgcacatgagcttc gaactgaagctgctgctgctcctgctgtggctgacggcctcctgctccctcttcttgcac tcccacgcctggctgtctgactgcctcatcgcccgcctctatctgggccccgcggattcc aggccaggggtgctgaaggagcccaaaatgatgggcgctatctccttcttcatcttcttc tttaccctccttgtcctggctcggcagaatgaatattactgccgcctggacttcctgtgg aagaagaagctgaggcaggagcgggaggagacagagacaatggagaacctgacccggctg ctcttggagaatgtgctccctgcgcacgtggccccccagttcattggccagaaccggcgc aacgaggatctctaccaccagtcgtacgagtgtgtttgtgtcctcttcgcctccgtccca gacttcaaggagttttactctgaatccaatatcaaccacgagggcctagagtgtctgcgg ctgctcaatgagataattgctgattttgatgagctgctctccaagcccaaattcagtggc gtggagaagatcaaaaccattggcagcacctacatggcagctacaggcttaaatgccacc tctggacaggacgcacagcaggatgctgagcgaagttgcagccaccttggcaccatggtg gaattcacggtggccctcgggtctaagctagatgtcatcaacaagcactcattcaacaac ttccgcttgcgtgtggggttgaaccacggaccagtagtggctggagtgattggggcccag aagccacaatacgacatctggggcaacacggtgaacgtggccagccgcatggagagtaca ggagtcctgggcaagatccaagtgactgaagagacagctcgggccctgcagtctttaggc tacacctgctacagccggggtgtcatcaaggtcaaaggcaaagggcagctctgcacctac ttcctgaacacagatttgacacgaactggacctccctctgccgccctgggctga

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