Echinicola strongylocentroti: DN752_10530
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Entry
DN752_10530 CDS
T05506
Name
(GenBank) bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase
KO
K01798
Alr-MurF fusion protein [EC:
5.1.1.1
6.3.2.10
]
Organism
est
Echinicola strongylocentroti
Pathway
est00300
Lysine biosynthesis
est00470
D-Amino acid metabolism
est00550
Peptidoglycan biosynthesis
est01100
Metabolic pathways
est01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
est00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DN752_10530
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
DN752_10530
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DN752_10530
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DN752_10530
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
est01011
]
DN752_10530
Enzymes [BR:
est01000
]
5. Isomerases
5.1 Racemases and epimerases
5.1.1 Acting on amino acids and derivatives
5.1.1.1 alanine racemase
DN752_10530
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DN752_10530
Peptidoglycan biosynthesis and degradation proteins [BR:
est01011
]
Precursor biosynthesis
Amino acid ligase
DN752_10530
Racemase
DN752_10530
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ala_racemase_N
Ala_racemase_C
Mur_ligase_M
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AWW30526
UniProt:
A0A2Z4IJ10
LinkDB
All DBs
Position
2720948..2723413
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AA seq
821 aa
AA seq
DB search
MVKSLTFQQLTLITQGQTVLQDREDQPVRYISTDSRKIIHGQQTLFIALKGFKVDGHDYL
KDAYEKGVRLFIVQKPLLLNQFPGIAVLQVNDGLKALQAIAKWNRKQFGGTVIGITGSNG
KTIIKEWLGQVLASKFALAKSPKSYNSQTGVPLSIFGIEEYHKAAIIEAGISQVGEMARL
ERIIQPDIGILTNIGTAHAEGFSSQEQKLKEKIKLFNDAQLIIYRKDHPLIHRILQEHFA
PSRLVAWSEYAGADYTLSIKKNNNGSKITLIKPDLGIFTFHSPFTDEASLENLRHTMVAS
LVLGLPEPEIQQVIPGLNTVEMRLTLKSGIHQCLLIDDTYNNDLAGLDIALEFMNTQRPK
KRKILMLSDLLQAGKKEDVYNNVRALVRHYQVDMLLGVGQEISQLEENPPCESHFYQDTD
QLLEALGTLSFQDDLILIKGARMYRFEQIVDALQERLHGTVLEINLNALRRNFTFYKSQL
KPSTKVMIMVKAFAYGGGATEIAHHLQQLNADYLAVAYTDEGVSLRQEQINLPIMVLNPA
PESFGNLVKYQLEPVVYSLSFFRQLGAYCHSNHTSLKIHLDLDTGMHRLGFGETDLEALR
EMITAYPSLKVASMYTHLAGADEADHEEYTKRQLSLFEAMCKTVKGFLGYSPLVHALNSA
GIVRYPDFQMDMVRLGIGLYGVEVNGLHQEALQPVSVLKTTISQLKSLKKGETVGYGRKG
VMASDGQIATIAIGYADGYDRRFSNGKGQVLIHGKKAAVIGNVCMDMTMIEVTGMDVHEG
DEVIIYGEGLSLKEQATAIGTIPYELLTNISSRVKRVYFMD
NT seq
2466 nt
NT seq
+upstream
nt +downstream
nt
atggtaaaaagcctcacgtttcagcaattgacccttatcacccaaggccaaaccgtcctg
caagacagagaagaccagcctgtcaggtacatcagtacagattccagaaagatcattcat
ggccagcagacgctgtttattgccttaaagggatttaaggttgatggccatgattatcta
aaagatgcctacgaaaaaggggtgcggctctttattgtacaaaaaccgctactgctcaat
caatttccggggattgcggtcttgcaggtaaatgacggtctgaaggcattacaggccatt
gccaaatggaatcgaaagcaatttgggggtactgtcataggcattactggcagtaatggc
aaaacgatcataaaggaatggctcgggcaggtgctggcgagtaaatttgcgcttgcaaaa
agccccaaaagctataacagccagacgggagtgccgctctcgatatttggaatcgaagag
tatcataaagctgccattatcgaagctggtatatcacaagtgggcgaaatggcaagactc
gaacgtatcatccaaccggatatcggcattctgaccaatatcggcactgcacatgcggaa
ggtttttccagccaagagcaaaaactaaaggaaaaaataaagcttttcaatgatgcccaa
ctgatcatttacagaaaggaccacccactcatccaccgcattttacaagagcattttgct
ccctcaaggctggtagcgtggtccgaatacgctggtgctgactatacactgtccatcaaa
aaaaacaacaatggaagcaaaatcacattgatcaagcctgacctgggcattttcaccttc
cacagtcccttcacggacgaagcatcattagaaaatctgcgacatacaatggtggccagc
ttggtactggggctgcctgaaccggaaatccagcaggtcattcctgggctaaacactgtg
gaaatgcggcttacgctcaagtcaggaatccaccaatgcctccttatcgatgacacctac
aataatgacttggctggactcgatatagcactggagttcatgaatacccaacggcccaaa
aagagaaaaatactgatgctctccgacctattgcaggcaggaaaaaaagaagatgtctac
aataatgtcagggcactggtcaggcattaccaagtggacatgttgctgggcgtgggacag
gaaatcagccagttggaagaaaatccaccatgcgagagccatttttatcaggacaccgat
cagcttttggaagctttgggcacgctatcatttcaggatgacctgatcttgatcaaggga
gcgaggatgtaccggtttgagcaaattgtggatgcgctgcaagagcgccttcacggtact
gtactagagattaacctgaatgcactcagaagaaattttactttctacaaaagtcaattg
aagccatctaccaaggtaatgatcatggtaaaggcttttgcctatggaggtggagccacc
gaaatagcccaccacctacaacagctcaatgcggactacttagctgtagcctatacagat
gaaggtgtcagcttacgtcaagaacagattaacctgccgatcatggtgctcaatcctgca
ccagaatcttttggcaacctcgtaaagtaccagctcgaaccggtggtatatagcctgagc
ttctttaggcaactgggagcctattgccattccaatcataccagcctaaaaatccacctt
gacctggacacgggaatgcacagattagggtttggagaaaccgacttggaagccttaagg
gaaatgatcacagcctacccgtccttgaaagtggccagtatgtacactcatctggccggt
gctgatgaagccgaccacgaagaatacaccaagcgccaactgtccctattcgaagccatg
tgcaagacggtcaaaggttttctgggctattcccctttggtacatgcgctaaactcagcg
ggcattgtccgctatccggattttcaaatggacatggtaaggctgggaataggcctgtat
ggcgtagaagtcaacggcctccaccaagaagcactccagccggtaagtgtgctgaagact
accatctcacaactcaaatcgctcaagaaaggtgaaacggtaggttatggccggaaagga
gtgatggccagtgatggccagatcgccactattgccatcggatatgcagatggctacgac
agaagattcagcaacggtaaaggccaagtgcttatccatggaaaaaaagccgccgtgatc
gggaatgtatgtatggacatgaccatgatagaggtcaccggaatggatgtccacgaaggg
gatgaagtcatcatctatggagaaggattgtccctgaaagaacaggctactgccattggc
actattccctatgagctactgaccaacatcagcagtagggtaaagcgggtttattttatg
gattga
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