KEGG   Frankia sp. EAN1pec: Franean1_7137
Entry
Franean1_7137     CDS       T00608                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K15739  D-alanine---(R)-lactate ligase [EC:6.1.2.1]
Organism
fre  Frankia sp. EAN1pec
Pathway
fre01502  Vancomycin resistance
fre02020  Two-component system
Brite
KEGG Orthology (KO) [BR:fre00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    Franean1_7137
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Franean1_7137
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:fre01504]
    Franean1_7137
Enzymes [BR:fre01000]
 6. Ligases
  6.1  Forming carbon-oxygen bonds
   6.1.2  acid-alcohol ligases (ester synthases)
    6.1.2.1  D-alanine---(R)-lactate ligase
     Franean1_7137
Antimicrobial resistance genes [BR:fre01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Lac type [MD:M00651]
    Franean1_7137
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp ATP-grasp_4 ATP-grasp_3 CPSase_L_D2 ATPgrasp_ST TTL ATPgrasp_YheCD
Other DBs
NCBI-ProteinID: ABW16458
RhizoBase: Franean1_7137
UniProt: A8L665
LinkDB
Position
complement(8717659..8718705)
AA seq 348 aa
MDRLRIGIIFGGRSEEHPVSVRSAQEIAKNIDAEKYEPFYIGIARSGAWKLCERPDENWE
NGSCRPAVLSPDRSVHGLLVLEQGRYETISLDLALPVLHGRLGEDGAMQGLLELSGIPYV
GCDVQSSALCMDKSLAYTVARGAGIATPNFWTVTANEKVDADLLTYPVFVKPARSGSSFG
VSKVSRKEELSGAVDTARQYDSKVLIEEAVVGSEVGCALLGNDLDLTAGEVDRISLSHGF
FRIHQESAPESGSENSTAIVPADISAEARSLVQETAKAVYRALGCRGLSRVDMFLQEDGK
VVLNEVNTLPGMTSYSRYPRMMAAAGLPLAEVIDRLVSLTLAGKVDEG
NT seq 1047 nt   +upstreamnt  +downstreamnt
atggatagactgaggatcggaatcatattcgggggccgttccgaggagcatcccgtctcc
gtccggtctgcacaggagatcgcaaagaacatcgatgccgagaagtacgaaccgttctac
atcgggatcgcgaggagcggtgcctggaagctgtgcgaacgccctgacgaaaattgggag
aacggcagctgccgtccggctgtgctgtcaccggacagaagcgtccacgggttgctggtt
ctggagcagggaagatacgaaacgatcagcctggacctggcgttgcccgttctgcacggc
agactcggcgaggacggtgcgatgcagggtctgctggagctctccggcatcccctacgtg
ggctgcgatgtccagagttccgctttgtgcatggacaagtcccttgcctacaccgtcgcc
agaggcgcgggaattgctacgccgaatttctggaccgtgacggcgaacgagaaagtggat
gccgacctgctcacctatcccgtattcgtgaagccggcccgttcggggtcatccttcggc
gtcagcaaggtgtctcgaaaagaagagctgtcgggtgcagtggataccgcacgacagtac
gactcgaaggtgctgatcgaagaggctgtcgtcggcagcgaggtcggatgtgccctgctg
gggaacgatctggatctgaccgcgggcgaggtagatcgaatctcgctgtctcatggattt
ttcaggatacatcaggagagtgcgcctgaaagcggttccgagaactcgacggcaatcgtt
ccagcggacatctcggcagaggcgcgctcgctcgttcaggagacggcaaaggccgtctat
cgcgccctgggatgcaggggcctgtcgcgggtggacatgttcctgcaggaagacgggaaa
gtagtcctcaacgaggtaaacaccctgcccggcatgacatcgtacagccgttatccgaga
atgatggcggccgcggggctgccgctcgccgaggtgatcgaccggctggtgtcgctgaca
ttggcgggaaaagtcgatgaaggatga

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