Francisella tularensis subsp. novicida F6168: AS84_1011
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Entry
AS84_1011 CDS
T03873
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ftd
Francisella tularensis subsp. novicida F6168
Pathway
ftd00010
Glycolysis / Gluconeogenesis
ftd00020
Citrate cycle (TCA cycle)
ftd00620
Pyruvate metabolism
ftd00785
Lipoic acid metabolism
ftd01100
Metabolic pathways
ftd01110
Biosynthesis of secondary metabolites
ftd01120
Microbial metabolism in diverse environments
ftd01200
Carbon metabolism
ftd01210
2-Oxocarboxylic acid metabolism
Module
ftd_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ftd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
AS84_1011 (aceE)
00020 Citrate cycle (TCA cycle)
AS84_1011 (aceE)
00620 Pyruvate metabolism
AS84_1011 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AS84_1011 (aceE)
Enzymes [BR:
ftd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
AS84_1011 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AJI44992
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Position
1046361..1049042
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AA seq
893 aa
AA seq
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MSDFTKDIDVLETQEWLEAFEDVVKREGADRAKFLFEQLLAKGSELGIKSAYSTAKVKNY
VNSIDVSEQPSYPGDIELEQKIEAINRWNSTVIVAAANKKDGSIGGHIGTGAGAMTLYEV
GFNHFWKAPNDEHAGDLIFYQGHLSPIVYARSFLEGRITAEQLENFRKQAFNGQNAVSSY
PHPYLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAKTSDRKVWAFCGDGEMDEPE
SIGSITRAGREGLDNLIFVVNCNLQRLDGLVNGNGNIVEELADVFAGAGWNVIKVLWSSD
WDKLLQDPRGGKKLAQRLSELNDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMTDDDI
QALRRGGHDPLKIYAAYKKAVENPNGRPTLILPMTVKGYGLGEWGESKNIAHNVKKLDTD
ALEHIKNRFNVPASKEDVENYRLIKLDENSPEMKYLHSKRKDLGGYIPKRLENKQALDIP
SYKDFAKSLLDDSGDREFSTTTAFVRILSHLAKDKNLGKHIVPITVDESRTFGMEGLFRQ
LGIYNPHGQQYVPEDKQQVMFYKESVDGQILQEGINEQGGFCSWIAAATSYSVHKVPMIP
FMIYYSMFGFQRFGDLAWAAGDSMAKGFVIGGTSGRTTLNGEGLQHEDGHSHIQAGLIPN
CISYDPTYAYELAVILGEGMKRMYVDGDHVYYYITVMNENYSHRAMPEGCEEGIIKGLYK
LDEEKKPAAKHVQLLGSGSILREVEAAAKMLKEEYGITSNVWSMTSANELYREAKDVART
NMLHPTAEKKESYIEKCFKNEQGPVIASTDYIKLYTDQLREFIPHTFVNLGTDGFGRSDT
RAALRSFFEVDRYHVVVASLYALYLDGKVEASEVKAAIEKYNIDPERMAPFYS
NT seq
2682 nt
NT seq
+upstream
nt +downstream
nt
atgtcggatttcactaaagatattgatgttttagaaacccaagaatggcttgaggctttt
gaagatgtcgtaaaaagagaaggtgctgatagagccaagtttttatttgaacaattactt
gctaaaggttccgagcttggtataaaaagtgcttactcaactgctaaagttaagaactat
gtcaactctatagatgtctctgaacaaccaagttatccaggagatatagagcttgaacaa
aagattgaagctatcaatagatggaactctacagttatagtagctgcagctaataagaaa
gatggctctataggtgggcatattggtactggtgccggcgctatgacgctttatgaagta
ggcttcaaccatttttggaaagcaccaaatgatgaacatgctggtgatttgatattctat
caaggacatctttctcctattgtttatgcgcgttcattcctagaaggtagaataactgca
gaacagttagaaaactttagaaagcaagcatttaatgggcaaaatgcggtatcttcatat
cctcatccttatctacaacctacttattggcagttcccaactgtttctatggggttagga
ccacttcaagctatttatcaagctagatttatgaagtatctagaggctagaggtttagca
aaaacatctgatcgcaaagtttgggcattctgtggtgatggcgagatggatgagccagaa
tcaattggttctatcactagagcaggtcgtgaagggctagataaccttatatttgtagtt
aattgtaatctacaaaggctagatggtctggtaaatggtaatggtaatattgttgaagaa
ttagcagatgtatttgctggagctggttggaatgttatcaaggtgttgtggagtagtgac
tgggataaattattacaagacccaagaggtggtaaaaaacttgctcaaaggttaagtgag
ttaaatgatggacaattccatacaattaaagctcatggtggtgctgagtgtcgtagagtt
gtctttagtggtgatgaagatttagaggcgttagctaaggatatgacagatgatgatatt
caagcattacgtcgtggtggacatgatccattgaaaatttatgcagcatataagaaggct
gtagagaatccaaatggtcgtccaacactaattcttcctatgactgttaagggctatggt
ttaggtgagtggggtgagtcaaaaaatattgcacacaatgtcaaaaaacttgatactgat
gcacttgagcacatcaaaaatagattcaatgtcccggcttcaaaagaggatgttgagaac
tatagacttatcaagctagatgaaaactcgccagagatgaaatatctacactctaagaga
aaagatctaggtggctatattcctaagagattagagaataagcaagcattagatattcca
agctataaagattttgctaagagcttattggatgatagtggtgacagagagttttcaact
actaccgcatttgtaagaatattatcccacttggcaaaagataagaatctagggaagcat
attgtaccaatcacggtagacgagtcacgtacttttggtatggagggcttgtttaggcaa
ttaggtatctataacccacatggtcagcaatatgtgccagaagataaacagcaagtaatg
ttctataaagaatctgtagatggtcagattttacaagaaggtattaatgagcaaggaggt
ttttgttcttggattgccgcagctacttcatatagcgtacacaaggttccaatgattcct
ttcatgatttactactcaatgtttggtttccaaagatttggtgatcttgcttgggcagct
ggcgattcgatggcaaaaggttttgtaattggtgggacttcaggacgtacaactctaaat
ggcgaaggtttgcagcatgaagatggtcatagccatatccaagctggtcttatacctaat
tgtatctcttatgatcctacatatgcttatgaattagctgtaatccttggcgaaggtatg
aagagaatgtatgttgatggtgatcatgtatattactatatcactgtaatgaatgagaat
tactctcatagagctatgccagagggttgtgaagaaggtattatcaagggtttatataag
ttagatgaagagaaaaagccagcggctaaacatgtacagttattaggttctggttctatt
ctaagagaagttgaagctgcagctaagatgctaaaagaagagtatggaattacttctaat
gtttggagtatgacttcagcaaatgagctttatagagaagctaaagatgtagctagaact
aatatgcttcatccaacagcagagaaaaaagaaagctatatcgagaagtgctttaaaaat
gagcaaggtcctgtaatcgcttctactgactatattaagctttatactgatcagttaaga
gagtttataccgcatacttttgtgaacttaggtacagacggctttggtagatcggatact
cgagcagcgctaagaagtttctttgaggttgatagatatcatgtcgttgttgcttcatta
tatgctctatatttagatggcaaagttgaggctagcgaagttaaagctgcgattgagaag
tacaatatagatccagagcgtatggcacctttttatagctaa
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