Gallus gallus (chicken): 427844
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Entry
427844 CDS
T01006
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
gga
Gallus gallus (chicken)
Brite
KEGG Orthology (KO) [BR:
gga00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gga01001
]
427844 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
gga04131
]
427844 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
gga04147
]
427844 (LRRK2)
Enzymes [BR:
gga01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
427844 (LRRK2)
Protein kinases [BR:
gga01001
]
Serine/threonine kinases: TKL group
LRRK family
427844 (LRRK2)
Membrane trafficking [BR:
gga04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
427844 (LRRK2)
Exosome [BR:
gga04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
427844 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Roc
COR
LRR_8
LRR_4
Ras
Arf
LRR_1
LRR_9
Ank_2
Gtr1_RagA
Arm
T2SSE
PUF
AAA_22
AAA_16
TrwB_AAD_bind
PduV-EutP
NACHT
Ank_4
ABC_tran
AAA_7
nSTAND3
AAA_29
MMR_HSR1
FtsK_SpoIIIE
MobB
TFCD_C
NB-ARC
Septin
cobW
Kdo
AAA_23
Motif
Other DBs
NCBI-GeneID:
427844
NCBI-ProteinID:
NP_001274122
CGNC:
53208
Ensembl:
ENSGALG00000007161
LinkDB
All DBs
Position
1:complement(15133563..15199297)
Genome browser
AA seq
2557 aa
AA seq
DB search
MASGCPWERVAATGEEEALRKLLVRLRNVQERKRPETLVQTLSDMLELAARQSGKGRPLP
ACPPDPAPPGPNAALRVPAAPRLFGGCNAHVPLLLVLDLYAGAAGVQQMGWSLLCKLIEI
CPSTLQNIALKDVGKDWEVLGVHQQILKMLTVHKGNVNLSVIGLKTLNLLLVSDVIAFLL
LEEEVDVFSLVFNAMHTFPKNEEIQQHGCRALYKLFEKVPEEQLTEFVESKDHMIILDVF
KEFPEKEEVILPALYSLHSLAGPPSNVEVLMSGNVRCYNVIVEMMKNFPNSETVQEVCCC
LLHKLTLGNFFNILVLHKVPEVIVKAVKTYSENAKLQAAALSCLALLTETIFLNRDLEER
KEEEEEEKLCWLEACYRALELHRKHTDVLEAACWALKNLFLYQRSLHEKIGDGDNQFPID
RAVMLSMLMHSSSKEVFQAAASTLAILSQQNVNIRKTLLAKGIHMNVLDIMRKHPHSPEV
AESACRILNHVFEGSFPHLDIMTVAASEVIKAMRKHEKSPSVQLEALRVLLHFMMPDTKN
DQNSSSRSMGDAAFTLTVKVIKSQCLLEGTHSLVLGALNRFIGNPSIQRCGLKLLTSVAE
CTGALEILTQQGATDTVLHTLQMYPDEQDIQSLGLSLLLFLITRKSLCIATMHVLATVLV
STLRRFKEVTEIQMHGFHAVLSILGFSPCFAKLLIHESFDTVIFYQMSMCFTNQRDRQFQ
SLCCKCFAKIAENDDLKNMMLEKACLEYNSIMAECLLLLGADINKKTKTNSLIYQVCEKG
NNPKLVELLLANGAREQDVRSALTISIKRGDSQIISLLLKKLSLDVANSSICLGGFGIGR
LEPSWLIPLFPDKLTPPRRQNAGSALARMVLKYQMKDISEDRSGASSDLNFSEDGVDKNY
DWNFISDPLVDTVFPSSDDIDSEGSEGSVFRKKKSNSIAVADLHCRELAFQRGSPTLPRH
SYSVGPGSDYEPLVKQRRKLLPSDEPLKGISKSSLHLRPSDSLSSLISEKECIKSLDLSS
NELENIDAISQNSSLMSHLEHLDKLELHQNALTNIPEQLCENLKCLTYLDLHSNRFTSFP
TYLLKMNCIAYLDISRNDIGPSFALDPYLRCPTLKQLNLSYNQLMCIPEFLANVAENLEQ
LLLEGNKISCLSAPVSLKELKILNISKNNISSLAENALTGCTKLELFNARMNALEIIPDL
SSSITTLKLSQNCFINVPEAILLLPHLRSVDLSQNKIISLPGPVHWKSLNLRELLFNHNQ
IGVLDLSEKACAWSRLEKLHLSNNKLKEIPPQIGFLENLTSLDVSHNPDLRFFPDEMGKL
SKIWDLPLEGLHLNLDFKHVGCKARDIIRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLL
QQLMKCKRTELGCPKATVGIDVKDWIIQGKGKMKKELILNVWDFGGQEEFYSTHPHFMTQ
RALYLAVYDLSKGQAEVDAMKPWLFNIKARASTSPVILVGTHLDVSDEKQHKDCMSKITR
ELLNKRGFPAIQDYHFVNAKEESDSIMRLRKIIIKESLHFKIRDQPVVGQLIPDSYLELE
RRILLERKNVPVEFPVIDQKRLLEMVQENKLQLDENELPHAIHFLNESGVLLHFQDPALQ
LRDLYFVDPKWLCKIMAQILTVKVEGFSKYPKGIVKRSDVEKFLLKKSKFPKIYMSQYFK
LLEKFQIALPLGEDQLLIPSSLSDHRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLINR
LLEISPYMLSGRARALRPNRMYWRQGIYLNWSPEAYCLVESAVFDNNPDSFLKITAPSCR
KGCILLGQVVDHIDSLMEEWFPGLLDIDVCGEGETLLKKWALYSFEDGEEHQKILLDDLL
KKAEEGDLLVNPEQPRHTIPIAQIAPDLILADLPRNIMLNTDELEFDKAPEFLLGDGGFG
SVYRASYGGEEVAVKIFNKHTSLRLLRQELAVLCHLHHPSLVSLLAAAVRPRMLVMELAL
KGSLDRLLQQDKANLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAV
IAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDILTGGG
RIMEGVKFPNEFDELAIQGKLPDPVKEYGCAPWPKVEHLIKKCLKENPQERPTSSQVYEI
LNSAELICLMRYVSIPSTSTAECMVAANQSCKKAGVWIGNGNTEKAQLSFVNLNTDGHTC
EDIADSKILSLALVTLPTEKENWIVAGTHSGSLWAVNTEDETRRHRLQKMSDSVTCLYCN
SLSKQSKQKNFFLVGTADGTLAVFEDRAVKCKGATPLKILTIGNVSTPLMCLNESTYLSE
KNTIWGGCGTKLIALSSDFSVQKLIETKSSQLFCHNAYSDANIISIAVDKSIYLAKKNSH
FVEIWDKKTEKLSELIDCAHFLKDEVEKLNKESKHKVAYSGRVKTICLQKNTALWVGTGG
GHILLLDLSTRRPVRVIDNFCDSIRVMLTAQLGSLKNVVLVLGYCYKSDTEDDKSHKELQ
SCVSVWDINLPHEVQNLKKHIEVRQELAEKMKSFTLD
NT seq
7674 nt
NT seq
+upstream
nt +downstream
nt
atggccagcggctgcccctgggagcgggtggcggcgacgggagaggaggaggcgctgagg
aagctgctcgtccggctccgcaacgtccaggagaggaaacggccggagactctggtgcag
acgctgagcgacatgctggagttggcggcccggcagagcggtaaggggcggccgctgccc
gcctgccctcccgaccccgctccgcctggccctaacgcagctctccgtgtccccgcagct
ccgcggctgttcggcggctgcaacgcccacgtgcccctgctgctggtgctcgacctgtac
gcgggagcggccggcgtgcagcagatgggttggtcgcttctttgcaaattgatagaaatt
tgtccaagtactctacagaacatagctcttaaggatgttgggaaggactgggaagtactg
ggtgttcaccagcagattcttaaaatgctcacagtccacaaaggaaatgtaaatctctca
gtaataggactaaaaacattaaatctactcctggtgtcagatgtaattgctttcctgctc
ctggaggaagaagtggatgtgttttccctggtatttaatgccatgcacactttccctaaa
aatgaagagatccagcaacatggatgtagagcattatacaagctttttgaaaaagttcca
gaagagcagctgactgaatttgttgaaagcaaagatcatatgatcatactggatgtattt
aaagagtttccagagaaagaagaggtgattcttcctgcactttattcattacattcctta
gctggtccacccagcaatgttgaagtgctcatgtctggaaatgttcgctgctacaatgtt
atagtagaaatgatgaaaaatttccccaatagtgaaactgttcaggaagtgtgttgctgc
ttgttgcataagcttacattgggaaactttttcaatatccttgtgttacataaggttcca
gaagtcattgtgaaggctgtgaaaacatattctgaaaatgcaaagttacaggctgcagct
ctcagttgtttagctcttctcactgaaacaatattcttaaaccgagacttagaggaaaga
aaagaagaggaggaagaagaaaaattatgctggttggaagcatgttacagagcattagaa
ctgcaccgaaaacatacagatgtactggaggcggcatgctgggctttgaaaaatctgttt
ctgtatcaacgcagtcttcacgagaagattggagatggagataatcagttccccatagat
agagcagtgatgctgtccatgctgatgcactcctcttcaaaagaagtgtttcaggcagca
gctagtaccttggcaattttgtcacaacagaatgtaaatattaggaagacacttttggct
aaaggaatacacatgaatgttttggatataatgaggaaacacccacattctcctgaagtg
gctgaaagcgcctgcagaattctgaatcatgtttttgaaggaagtttccctcatttggat
ataatgacagtagctgcatctgaagtcataaaagccatgaggaaacatgaaaaatcaccc
tctgtacaactggaagcacttcgagtccttttacactttatgatgcctgatacaaagaat
gatcagaacagttcttccagaagtatgggagatgctgctttcacgctcacagtaaaagtc
attaaaagccagtgtctgctggagggaactcattccttggtgcttggtgctttgaacagg
tttattggaaatcctagcattcagaggtgtggattaaaactacttacttctgtagctgaa
tgcacaggtgctttagaaattttaacacagcaaggagccactgacactgtgcttcacacc
ctgcagatgtatccagatgaacaagacatacagagtttgggtttgagtcttctgctcttt
ttgattacaagaaagagtttgtgtattgcaactatgcatgtcctggcaactgttctggtt
tctactctgcgacgctttaaagaggtcactgaaatccagatgcatggatttcatgcagtc
ttgtcaattcttggtttttcaccttgttttgccaagctgctgatacacgaatcatttgac
acagtaatcttctaccagatgtctatgtgcttcactaaccaacgagatcgacagtttcaa
agcctgtgttgtaaatgctttgctaagatagctgaaaatgatgatttaaaaaatatgatg
cttgaaaaagcatgtctcgagtacaatagtattatggctgaatgtttacttctactggga
gctgatattaataagaagacgaaaacaaactctttgatctatcaggtttgtgaaaaagga
aataatcctaaactggtggaattgctattagccaacggtgctcgagagcaggatgttcgg
agtgctttaaccatcagtataaagagaggagatagccaaatcatcagcttgctcttaaag
aagcttagccttgatgtcgccaacagcagtatatgtcttggaggatttggtattgggaga
cttgagccttcctggctcattcctttgttcccagataagcttactccaccaagaaggcaa
aatgcaggctctgcactggcacgaatggtgcttaaataccagatgaaggatatttcagag
gatagatcaggagcttcttctgatttaaacttctctgaagatggagtggataaaaactac
gattggaatttcatttctgacccattagtggacactgtttttccttcgagtgatgatatt
gacagtgaaggaagtgaaggttcagtttttagaaaaaagaagtccaattccattgcggtt
gctgatttacattgtagagaacttgcttttcaaagaggttctcctactttaccacgacat
tcctactctgtgggacctggctcagattatgagccattagtgaaacaaagaagaaaatta
ctgccttcagatgaacctctcaaaggaatctcaaaaagctcactgcatttaagaccatca
gacagtctttcctcattgatctcagagaaggaatgtattaaatcactagatctttcatca
aatgagctggagaacatcgatgccatcagccagaacagtagcttaatgagtcacttggaa
caccttgataaactggaactccaccaaaatgctcttacaaacattccggaacaactgtgt
gagaacttgaaatgcttgacttatttggatttgcacagcaaccgatttacttcttttcct
acttatttgctgaaaatgaactgtattgcctatcttgatatctctcgaaatgacattgga
ccttcctttgctttggatccatatctcagatgtccaaccctaaagcaacttaatctttca
tacaatcagctgatgtgcattcctgagtttcttgcaaatgttgctgagaacctcgaacag
ctattgctggaaggaaacaaaatttcatgcttatctgcacccgtgtccttgaaagagctg
aaaattttaaatatcagtaagaacaatatttcatcccttgctgagaatgcgttaacgggc
tgtacaaaactggagctgttcaatgccaggatgaatgctcttgagataatacctgacttg
tcatctagcataacaaccttaaaattatcccaaaattgctttattaatgttccagaagcg
attcttcttctaccacatttgcgatcagtagatttaagccaaaacaagatcataagcctg
cctgggccggtgcactggaaatcactgaacttaagggagctgttatttaatcataatcaa
attggagtcttggacttgagtgaaaaggcatgtgcgtggtctaggctagaaaagctacac
ctgtccaacaacaagttaaaggagatacctcctcagattggcttcctagaaaacttgact
tctctggatgtaagtcataatcccgatttgagattctttccagatgaaatgggaaagctg
tccaaaatttgggatcttcctttggaaggactccatcttaacttggacttcaaacatgtg
ggatgcaaagccagagacatcatcagatttcttcaacaacgactgaagaaggctgtacct
tataacagaatgaagctaatgattgttggaaacactggtagtggaaaaactacactgttg
caacagctaatgaaatgcaaacgaactgagctgggctgtccaaaagctacagtaggcatt
gatgtaaaagactggatcattcaagggaaaggcaaaatgaagaaagagcttatattaaat
gtctgggattttggaggacaagaggagttctacagtacccatcctcacttcatgacccaa
agagctttatatcttgctgtttatgatctcagcaaaggacaagcagaggtggatgctatg
aagccatggctttttaacatcaaggcacgagcttcaacatcccccgtcatacttgttggc
acccacttagatgtttctgatgaaaagcaacataaggactgcatgagtaaaattactaga
gagcttttgaataagcgaggcttcccagcaatccaggattatcactttgtgaatgctaaa
gaagaatcagattccattatgagacttcggaaaatcataataaaggagagtcttcatttc
aaaatcagagatcaaccagtggttggtcagctaattcctgacagctatctggagctggag
aggagaattttgctggaaagaaaaaatgtcccagttgaatttcctgtgattgatcagaaa
cgattactagaaatggtacaagaaaacaagttacagctggatgaaaatgagctccctcat
gcaattcactttctgaatgaatcaggtgtactgcttcattttcaggacccagcgctccag
ctaagagatctgtactttgtagatcctaaatggctatgtaaaatcatggcacagattttg
actgtgaaagtggaaggcttttctaaatatcctaagggaattgtaaagcgctcagatgtg
gaaaaattccttttaaagaagagcaagtttcctaagatctacatgtcacaatacttcaaa
cttctggaaaagtttcagattgctttgccattaggagaggaccaactactaatcccaagc
agtttgtctgatcacagacctgttatagagcttcctcactgtgaaaattcagaaattatc
atcagactttatgagatgccatactttcctatgggattttggtccaggctgatcaacagg
ttgcttgaaatatcgccttatatgctgtcaggaagagcacgagctcttcgtcctaacaga
atgtattggagacaaggcatctacttgaattggtctcctgaggcttattgtctggtggaa
tcagctgtatttgacaacaacccagacagttttttgaaaattacagcaccttcttgcaga
aaaggttgcatccttttgggacaagttgtggatcacattgattctcttatggaagaatgg
tttccaggtttgctggatatagatgtgtgtggtgaaggggaaacactgttgaagaaatgg
gctctgtacagttttgaggatggtgaagaacaccaaaaaatactacttgatgacttactt
aaaaaagctgaagaaggagacctcttagtaaacccagagcagccaagacataccattccc
atcgctcagattgctcctgatctgatcctggctgacttgcctagaaacattatgctgaac
actgatgagctggaatttgacaaagctcctgaatttctcttgggtgatggtgggtttgga
tcagtgtaccgtgcttcctatggtggagaagaagttgctgtgaagattttcaataaacat
acatccctcaggctcctaagacaagagcttgcagtgctttgtcacctccatcatcccagc
ttagtgtctttgctggctgctgctgtccgtccccggatgctggtgatggaattagccctt
aaaggatctcttgatcggttgcttcaacaagacaaggcaaacttaactagaacacttcag
cacaggatagctctacatgtagctgacggcttaaggtacctgcattcagcaatgatcatt
taccgtgatctgaagcctcacaacgtgttgctctttaccctatatcccaatgctgctgtc
attgcaaaaatagctgactatggcattgcccagtattgttgccgaatgggaataaaaacc
tccgaaggcacaccaggatttcgagcaccagaggttgccagaggaaatgttatttacaat
cagcaagctgatgtgtattcattcggtttgcttctctatgacattttaacaggaggaggt
agaataatggaaggtgtgaagtttccaaatgaatttgatgagctagcaatacaaggaaag
ttaccagatcctgtcaaagaatatgggtgtgctccgtggcctaaagttgaacatttaatt
aaaaagtgtttgaaggaaaaccctcaggaacgaccaacatcttcccaggtgtatgagatt
ttgaattccgcagagcttatctgtttgatgaggtatgtttcaatacccagcacttccaca
gcagagtgcatggtagctgccaatcaaagctgcaagaaggcaggagtctggataggcaac
gggaacacagaaaaagcacagctttcatttgttaacctaaatacagatggacatacttgt
gaggatattgcagatagtaaaattttaagtttggcgttggtgacccttcctactgagaaa
gaaaactggattgtggcaggaacccattctggttctctgtgggcagttaacacagaagat
gaaacaagacggcaccgtctgcagaagatgtctgattctgtcacgtgtttatactgtaat
tcactttcaaagcaaagcaaacagaagaatttctttctggtaggcacagctgatggtaca
ctggcagtgtttgaagacagagcagtaaagtgtaagggtgcaacacctttgaagatacta
actataggaaatgttagcacaccactcatgtgcttaaatgaatccacgtatttatctgaa
aaaaatacaatctggggaggctgtggaacaaagctcatagctttatctagtgatttctct
gtccaaaagctgattgaaacaaagtcaagccaactgttctgtcacaatgcttacagtgat
gcaaacattatttcaatagcagtagataaatccatctacttggcaaagaaaaatagtcat
tttgtggaaatctgggacaagaagacagaaaaactttctgaactaattgactgtgcccat
tttcttaaggatgaagtggaaaaactgaacaaagaatcaaaacataaagttgcttattct
ggaagagtgaagacaatttgcctgcagaaaaatactgcattgtgggtggggacaggagga
ggacatatcctgctacttgatttatcaacacgtcgtcctgtacgagttatagataacttc
tgtgactctattagagtcatgctaacagctcagcttgggagtctgaagaacgtggtgttg
gttttgggatactgctacaagagtgacaccgaagatgacaaatcccacaaagaattacaa
tcctgtgtgtcagtgtgggacattaacctcccccatgaagtgcaaaacctgaagaagcat
atagaagtgagacaggaactagccgaaaaaatgaagagcttcactttggactga
DBGET
integrated database retrieval system
