Gorilla gorilla gorilla (western lowland gorilla): 101148250
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Entry
101148250 CDS
T02442
Symbol
GAD1
Name
(RefSeq) glutamate decarboxylase 1
KO
K01580
glutamate decarboxylase [EC:
4.1.1.15
]
Organism
ggo
Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo00250
Alanine, aspartate and glutamate metabolism
ggo00410
beta-Alanine metabolism
ggo00430
Taurine and hypotaurine metabolism
ggo00650
Butanoate metabolism
ggo01100
Metabolic pathways
ggo04727
GABAergic synapse
ggo04940
Type I diabetes mellitus
Module
ggo_M00027
GABA (gamma-Aminobutyrate) shunt
Brite
KEGG Orthology (KO) [BR:
ggo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
101148250 (GAD1)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
101148250 (GAD1)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
101148250 (GAD1)
00430 Taurine and hypotaurine metabolism
101148250 (GAD1)
09150 Organismal Systems
09156 Nervous system
04727 GABAergic synapse
101148250 (GAD1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04940 Type I diabetes mellitus
101148250 (GAD1)
Enzymes [BR:
ggo01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.15 glutamate decarboxylase
101148250 (GAD1)
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GFIT
Motif
Pfam:
Pyridoxal_deC
Aminotran_5
Beta_elim_lyase
DegT_DnrJ_EryC1
SepSecS
OKR_DC_1
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
101148250
NCBI-ProteinID:
XP_018878027
UniProt:
A0A2I2ZG24
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Position
2B:57523106..57567694
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AA seq
594 aa
AA seq
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MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK
SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV
VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV
RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWS
SKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEQSHYSIKKAGAA
LGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIA
DICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKE
KGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQI
NKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPQRREKLHKVAP
KIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
NT seq
1785 nt
NT seq
+upstream
nt +downstream
nt
atggcgtcttcgaccccatcttcttccgcaacctcctcgaacgcgggagcggaccccaat
accactaacctgcgccccacaacgtacgatacctggtgcggcgtggcccatggatgcacc
agaaaactggggctcaagatctgcggcttcttgcaaaggaccaacagcctggaagagaag
agtcgccttgtgagtgccttcaaggagaggcaatcctccaagaacctgctttcctgtgaa
aacagcgaccgggatgcccgcttccggcgcacagagactgacttctccaatctgtttgct
agagatctgcttccggctaagaacggggaggagcaaactgtgcaattcctcctggaagtg
gtggacatactcctcaactatgtccgcaagacatttgatcgctccaccaaggtgctggac
ttccatcacccacaccagttgctggaaggcatggagggcttcaacttggagctctctgac
caccccgagtccctggagcagatcctggttgactgcagagacaccttgaagtatggggtt
cgcacaggtcatcctcgatttttcaaccagctctccaccggattggatattattggccta
gctggagaatggctgacatcaacggccaataccaacatgtttacatatgaaattgcacca
gtgtttgtcctcatggaacaaataacacttaagaagatgagagagatagttggatggtca
agtaaagatggtgatgggatattttctccggggggcgccatatccaacatgtacagcatt
atggctgctcgctacaagtacttcccggaagttaagacaaagggcatggcggctgtgccc
aaactggtcctcttcacctcagaacagagtcactattccataaagaaagctggggctgca
cttggctttggaactgacaatgtgattttgataaagtgcaatgaaagggggaaaataatt
ccagctgattttgaggcaaaaattcttgaagccaaacagaagggatatgttcccttttat
gtcaatgcaactgctggcacgactgtttatggagcttttgatccgatacaagagattgca
gatatatgtgagaaatataacctttggctgcatgtcgacgctgcctggggaggtgggctg
ctcatgtccaggaagcaccgccataaactcaatggcatagaaagggccaactcagtcacc
tggaaccctcacaagatgatgggcgtgctgttgcagtgctctgccattctcgtcaaggaa
aagggtatactccaaggatgcaaccagatgtgtgcaggatacctcttccagccagacaag
cagtatgatgtctcctacgacaccggggacaaggcaattcagtgtggccgccacgtggat
atcttcaagttctggctgatgtggaaagcaaagggcacagtgggatttgaaaaccagatc
aacaaatgcctggaactggctgaatacctctatgccaagattaaaaacagagaagaattt
gagatggttttcaatggcgagcctgagcacacaaacgtctgtttttggtatattccacaa
agcctcaggggtgtgccagacagccctcaacgacgggaaaagctacacaaggtggctcca
aaaatcaaagccctgatgatggagtcaggtacgaccatggttggctaccagccccaaggg
gacaaggccaacttcttccggatggtcatctccaacccagccgctacccagtctgacatt
gacttcctcattgaggagatagaaagactgggccaggatctgtaa
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