Galeopterus variegatus (Sunda flying lemur): 103588665
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Entry
103588665 CDS
T08727
Symbol
MYLK
Name
(RefSeq) myosin light chain kinase, smooth muscle isoform X1
KO
K00907
myosin-light-chain kinase [EC:
2.7.11.18
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr04020
Calcium signaling pathway
gvr04022
cGMP-PKG signaling pathway
gvr04270
Vascular smooth muscle contraction
gvr04371
Apelin signaling pathway
gvr04510
Focal adhesion
gvr04611
Platelet activation
gvr04810
Regulation of actin cytoskeleton
gvr04921
Oxytocin signaling pathway
gvr04971
Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
103588665 (MYLK)
04020 Calcium signaling pathway
103588665 (MYLK)
04022 cGMP-PKG signaling pathway
103588665 (MYLK)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103588665 (MYLK)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103588665 (MYLK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103588665 (MYLK)
09152 Endocrine system
04921 Oxytocin signaling pathway
103588665 (MYLK)
09153 Circulatory system
04270 Vascular smooth muscle contraction
103588665 (MYLK)
09154 Digestive system
04971 Gastric acid secretion
103588665 (MYLK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gvr01001
]
103588665 (MYLK)
Enzymes [BR:
gvr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.18 myosin-light-chain kinase
103588665 (MYLK)
Protein kinases [BR:
gvr01001
]
Serine/threonine kinases: CAMK group
MLCK family
103588665 (MYLK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
I-set
Ig_3
ig
Pkinase
Ig_2
23ISL
V-set
PK_Tyr_Ser-Thr
C2-set_2
fn3
Ig_4
Kinase-like
Kdo
AvrM_N
DUF5898
Motif
Other DBs
NCBI-GeneID:
103588665
NCBI-ProteinID:
XP_008568639
LinkDB
All DBs
Position
Unknown
AA seq
1960 aa
AA seq
DB search
MGDVKLAASSRVSKTSLSVDPSRIGSMPVMEAPAFILPPRNLCVKEGATAKFEGRVRGYP
EPQVTWHRNGQSITSGGRFLLHCGVRGTFSLVIHAVHEEDKGKYTCEAINGSGARQVTVE
LTVEGEFVKKHGQPVVSKTLGFSAPAVETHPSIWGECPPKFATKMGRAVVKEGQMGRFSC
KITGRPQPQVTWLKGNVPLQPSDRVSMSEKNGMQVLEIHEVTQDDVGVYTCMVVNGSGKA
STSAELSIQGLDNANRSFEKGTKATNSGIRREVTNGISKEPKPDSLETVAENKSCSSPQR
GSSPAWAMNSQSQPLRESKLEPGRDLPRKVLQTPVLQKTCSTITLQATKVQTETTAPVLG
ALSPSGEERKRPAAPHPATLPSRQSGLGSQEVVNKVATRKTSMESQRDSTFPRFESKPHS
QEVSEDQIVKFRCEVSGIPKPDVAWFLEGVPVRRREGTIEVYEDAGSHYLCLLRARARDS
GKYSCTAANIRGQVSCSWTLLVEKSAMMEVAPSFSSVLKDCTVIEGQDFVLQCSVQGTPV
PQITWLLNGWPIQYAHSTCEAGVAELHVQDALPEDNGTYTCLAKNALGQVSCSARVTVHE
KKSNGKSEYLQPMVPVFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED
FHFEQRGSRHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR
SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDIGHFEVLQNEDVFTLVLKNVQPRH
AGQYEILLKNQVGECSCQVSLMLQNSPASPTLRGREPASCEGLCGEGAGADGGGGDCYGT
LRPGWPARGQSWPKEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTK
TLSEEDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTPKTPVP
EKVPSPKPATPDFRSVLGSKKKLPAENGSSNAEALNAKAAESPKPSLKPVGNAKPAETLK
PVGNTKPAETLKPVGNAKPAEILKPVGNAKPAETLKPVGNAKPAETLKPVGNAKPAETLK
PVGNAKPAETLKSVGNIKPAETLKPAGKEELKKEVKNDVNCKKEHAGTTDNEKRPENQGT
APIFKEKLQDVHVAEGEKLLLQCQVSSDPLATITWTLNGKTLKTTKFIILSQEGSLCSIS
IEKALPEDRGLYKCVAKNSAGQAECSCQVTVDDAPASENAKAREMKSRRPKTSLPPVLGT
ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGEPVELFGKVAGSQPITCTWMKFRK
QIQESEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAG
TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSVDKTWKELATCRSTSFNVQDLLP
DHEYKFRVRAINVYGTSEPSQESELTAVGEKPEETKDEVEVSDDDEKEPEVDYRTVTVNT
EQKVSDFYDIEERLGSGKFGQVFRLVEKKTGKIWAGKFFKAYSAKEKENIRQEIGIMNCL
HHPKLVQCVDAFEEKANVVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI
HKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYE
PIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISNDAKDFI
SNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIG
RLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIR
DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD
DAKYTCKAVNSLGEATCTAELIVETMEEGEGDGEEEEEEE
NT seq
5883 nt
NT seq
+upstream
nt +downstream
nt
atgggggatgtgaagctggctgcctcatcacgtgtttccaaaacttccctcagtgtggat
ccctcgagaattggctccatgccagtgatggaggcccctgctttcattttgccccctcgg
aacctctgcgtcaaagaaggagccactgccaagtttgaagggagggtacggggttaccca
gagccccaggtgacgtggcaccgaaacgggcaatccatcaccagtgggggccgcttcctg
ctgcattgtggtgtccgggggactttcagcctcgtgattcatgctgttcatgaggaggac
aagggaaagtatacctgtgaagccatcaatggtagtggtgcccgccaggtgacagtggag
ttgacggtagaaggtgaatttgtgaagaagcatggtcagcctgttgtttctaaaaccctg
ggattttcagccccagcggtggagacgcatcctagcatctggggagagtgcccaccaaag
tttgctaccaagatgggccgagcagtggtcaaagaaggacagatgggacgattctcctgc
aagatcactggccggccccaaccacaggtcacctggctgaagggaaacgtcccactgcag
ccaagtgaccgtgtgtctatgtctgagaagaatgggatgcaagttctggaaattcatgaa
gtcacccaagatgatgtgggagtgtacacatgcatggtggtgaacgggtcagggaaggcc
tccacatcagctgagctttccatccaaggtttggacaatgccaataggtcctttgagaaa
ggaacaaaagccaccaattcaggcatcaggagggaggtgaccaatggaatctcgaaggag
ccgaaaccagacagcctggagactgtggccgaaaataaaagctgctccagcccccagaga
ggcagctccccagcctgggccatgaacagccagtctcagcccctgagagagtccaagctg
gagccaggcagggacttacccagaaaggtcctgcagacccccgtccttcagaagacttgc
agtaccatcaccctgcaggccacaaaagtccagacggaaacgacagcaccagtcttgggg
gccctctctccttctggggaagagaggaagaggccagcggctcctcatccagccaccctc
ccctccaggcagtctggcctgggaagccaagaagttgtgaacaaggttgctaccaggaaa
acctccatggagagccagagggattcgacgttccccagattcgagagcaagccccacagc
caggaagtcagtgaagatcaaatagtcaagttcagatgtgaggtttcagggatcccaaag
cctgacgtggcctggttcctggaaggtgtccctgtgaggagacgagaaggcaccatcgag
gtttatgaagatgccgggtcccattacctctgcctgctgagagcccgggccagggacagt
gggaagtatagctgcacagctgccaacatccgaggccaggtgtcctgtagctggaccctc
ctagtggaaaagtcagccatgatggaggtggccccctcattctccagtgtcctgaaggac
tgcactgtcattgagggccaggattttgtgctgcagtgctcagtgcaggggaccccagtg
ccccaaatcacttggctgctcaatgggtggcccatccagtacgcccactccacctgtgag
gccggtgtggcggagctccatgtccaggatgccctgccagaggacaatggcacctatacc
tgtctggccaagaacgccttggggcaggtgtcctgcagtgcccgggtcaccgtccatgag
aagaagagcaacgggaagagtgagtacctacagcccatggtgcccgtcttccttcagggc
ctgtctgatctcaaagtcatggatggaagccaggtcaccatgacggtccaggtgtcaggt
aatccaccccctgaggtcatctggcttcacaacgggaatgagatccaggagtcagaggat
tttcactttgaacagagaggctctcggcacagcctttgtatccaggaggtgttcccagag
gacactggcacatacacttgtgaagcctggaacagcgcgggagaggtccgcactcaggcc
gtgctcacagtgcaagagcctcatgatggcacccagccctggttcatcagcaagcctcgc
tcggtgacagcctccctgggccagagtgtcctcatttcctgtgccatagctggggatccc
tttcccactgtgcactggctccgagatggcaaagccctctgcaaagacattggccacttc
gaggtgctacagaatgaggatgttttcaccctggttctcaagaacgtgcagccccggcac
gctggccagtacgagatcctgctcaagaaccaggttggcgaatgcagttgccaggtgtca
ctgatgctacagaacagccctgccagccccaccctgcgggggagggagcctgccagctgt
gagggcctctgtggtgaaggagctggtgctgatggtggtggtggtgactgctatgggacc
ctgaggcctggctggccagcaagagggcagagttggcccaaggaggaagacggcgaggat
gtgcggggggtgctgaagagacgcgtggagacgaggcagcacacagaggaggccatccgc
cagcaggaggtggagcagctggatttccgtgacctcctgggcaagaaagtgagtaccaag
accttgtcagaagaagacctgaaggagatcccagcagagcagatggatttccgcgccaac
ctgcagcggcaagtgaagccaaagactgtgtccgaggaagagaggaaggtgcatagtccc
cagcaggtcgacttccgctctgtcctggccaagaaagggactcctaagaccccagtgcct
gagaaggtgccatctccaaaaccagccaccccggattttcgttcagtgctgggcagcaag
aagaaattaccagcagagaatggtagcagtaatgctgaggctttgaatgccaaggcagca
gaaagtcccaagccttccctgaaacccgttggcaatgccaagcctgccgagaccctgaaa
cctgtgggcaacaccaagcctgccgagaccctgaaacccgtgggcaatgccaagcctgcc
gagatcttgaaacccgtaggcaacgccaagcctgccgagaccctgaaacctgtggggaat
gccaagcctgccgagaccctgaaacccgtgggcaatgccaagcctgccgagaccctaaaa
cctgtgggcaatgccaagcctgccgagaccctgaaatccgtgggcaacatcaagcctgcc
gagaccctgaaaccagctgggaaagaagaactcaagaaggaggttaagaatgatgtgaac
tgcaagaaagagcatgcaggaaccacagataatgaaaaaagaccagagaaccaagggaca
gccccaatcttcaaggagaagctacaagatgtccatgtggcagagggtgagaagctgctc
ctccagtgccaggtgtcctctgaccccctggccaccatcacctggacactgaatggaaag
acactcaagactaccaagttcatcatcctctcccaagaaggctcactctgctccatctcc
atcgagaaggcactgcctgaggacagaggtttatacaagtgtgtagccaagaacagtgct
ggccaggccgagtgctcctgccaagtcaccgtggacgatgctccagccagtgagaatgcc
aaggcccgggagatgaaatcccggaggcccaagacctcgcttcctcctgtgctgggaaca
gagagtgatgcgaccgtgaaaaagaaacctgcccccaagacacctccgaaggcagctatg
ccccctcagatcatccagtttcccgaggaccagaaggtacgcgcaggagagcctgtggag
ctgtttgggaaagtggcaggcagccagcccatcacctgcacttggatgaagttccgaaag
cagatccaggagagcgagcacatcaaggtggagaacagcgagaacggcagcaagctcacc
attctcgctgcacgccaggagcactgcggctgctacacactactggtggagaacaagctg
ggcagcaggcaggctcaggtcaacctcactgttgtggataagccagaccccccagccggc
acgccttgcgcctctgatattcggagctcctcgctgacgctgtcctggtatggctcctcg
tacgatgggggcagcgctgtacagtcctacagcattgagatctgggactcggtggacaag
acgtggaaggaactagccacatgccgcagcacctcttttaacgtccaggacctgctacct
gatcacgagtataaattccgtgttcgtgcaatcaatgtgtatggaaccagtgagccaagc
caggagtctgaactcacagcagtcggagagaaacctgaggagacgaaggatgaagtggag
gtgtcagatgatgatgagaaggagcccgaggtggattaccggacggtgacagtcaatacc
gagcaaaaagtatctgacttctacgacattgaagagagactaggatctgggaagtttgga
caggtcttccgacttgtagaaaagaaaactggaaaaatctgggcagggaaattctttaag
gcatattcggcgaaagagaaagagaatatccggcaggagattggcatcatgaactgcctg
caccaccccaagctggtgcagtgcgtcgatgcatttgaggagaaggccaacgtcgtcatg
gtcctggagattgtgtcggggggtgagctgtttgagcgcatcatcgatgaggacttcgag
ctgacggagcgcgagtgcatcaagtacatgaggcagatctcggagggggtggagtacatc
cacaagcagggcatcgtgcacctggacctcaagcctgagaacatcatgtgtgtcaacaag
acaggcaccaggatcaagctcatcgactttggtctggccagaagactggagaatgcgggg
tctctgaaggtcctctttggcaccccagagtttgtggcccctgaagtgatcaactacgag
cccattggctatgccacggacatgtggagcatcggggtcatctgctatatcctggtcagt
ggactttcgcccttcatgggtgacaacgataatgaaaccttagccaacgttacctcagct
acctgggacttcgacgatgaggcattcgatgagatctccaatgatgccaaagattttatc
agcaatttgctcaagaaagatatgaaaaaccggctggactgcacccagtgccttcagcat
ccatggctaatgaaagacaccaagaacatggaggccaagaagctctctaaggaccgaatg
aaaaagtacatggcaagaaggaaatggcagaaaacaggcaatgctgtgagagctattgga
agactgtcctctatggcaatgatctcagggctcagtggcaggaaatcctcaacagggtca
ccaaccagcccgctcaatgcagaaaaactagaatctgaagaagatgtctcccaagctttc
cttgaggctgttgctgaggaaaagccccatgtaaaaccctatttctctaagaccattcgt
gatttagaagttgtggagggaagtgctgctagatttgactgcaagattgaaggataccca
gaccctgaggtcgtctggttcaaagatgaccagtcaatcagggagtcccgccacttccag
atagactacgatgaggatgggaactgctctttaattatcagcgatgtttgcggggatgac
gatgccaagtacacctgcaaggctgtcaacagtcttggagaagccacctgtacagcagag
ctcattgtggaaaccatggaggaaggggaaggggacggggaagaggaagaagaggaagag
tga
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