Galeopterus variegatus (Sunda flying lemur): 103595208
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Entry
103595208 CDS
T08727
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr01521
EGFR tyrosine kinase inhibitor resistance
gvr01522
Endocrine resistance
gvr04010
MAPK signaling pathway
gvr04014
Ras signaling pathway
gvr04015
Rap1 signaling pathway
gvr04066
HIF-1 signaling pathway
gvr04068
FoxO signaling pathway
gvr04114
Oocyte meiosis
gvr04140
Autophagy - animal
gvr04144
Endocytosis
gvr04150
mTOR signaling pathway
gvr04151
PI3K-Akt signaling pathway
gvr04152
AMPK signaling pathway
gvr04211
Longevity regulating pathway
gvr04213
Longevity regulating pathway - multiple species
gvr04510
Focal adhesion
gvr04520
Adherens junction
gvr04550
Signaling pathways regulating pluripotency of stem cells
gvr04730
Long-term depression
gvr04913
Ovarian steroidogenesis
gvr04914
Progesterone-mediated oocyte maturation
gvr05200
Pathways in cancer
gvr05202
Transcriptional misregulation in cancer
gvr05205
Proteoglycans in cancer
gvr05214
Glioma
gvr05215
Prostate cancer
gvr05218
Melanoma
gvr05224
Breast cancer
gvr05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103595208 (IGF1R)
04014 Ras signaling pathway
103595208 (IGF1R)
04015 Rap1 signaling pathway
103595208 (IGF1R)
04066 HIF-1 signaling pathway
103595208 (IGF1R)
04068 FoxO signaling pathway
103595208 (IGF1R)
04151 PI3K-Akt signaling pathway
103595208 (IGF1R)
04152 AMPK signaling pathway
103595208 (IGF1R)
04150 mTOR signaling pathway
103595208 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103595208 (IGF1R)
04140 Autophagy - animal
103595208 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
103595208 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103595208 (IGF1R)
04520 Adherens junction
103595208 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
103595208 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
103595208 (IGF1R)
04914 Progesterone-mediated oocyte maturation
103595208 (IGF1R)
09156 Nervous system
04730 Long-term depression
103595208 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
103595208 (IGF1R)
04213 Longevity regulating pathway - multiple species
103595208 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103595208 (IGF1R)
05202 Transcriptional misregulation in cancer
103595208 (IGF1R)
05205 Proteoglycans in cancer
103595208 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
103595208 (IGF1R)
05214 Glioma
103595208 (IGF1R)
05218 Melanoma
103595208 (IGF1R)
05215 Prostate cancer
103595208 (IGF1R)
05224 Breast cancer
103595208 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103595208 (IGF1R)
01522 Endocrine resistance
103595208 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gvr01001
]
103595208 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
gvr04090
]
103595208 (IGF1R)
Enzymes [BR:
gvr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103595208 (IGF1R)
Protein kinases [BR:
gvr01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
103595208 (IGF1R)
CD molecules [BR:
gvr04090
]
Proteins
103595208 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
DUF4476
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
103595208
NCBI-ProteinID:
XP_008576768
LinkDB
All DBs
Position
Unknown
AA seq
1366 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFLSATLLLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGAMEEKPLCEKTTINNEYNYRCWTPNHCQKMCPSTCGKRACTENNECCHSECLGSCS
TPDNDTACVACRHYYHAGACVPSCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSESMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHHNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPSNKDIEPGILLHGLKPWTQYAIYVKAVTLTMVENDHIHGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQQQPQDGYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTVADAYNITDPEELETEYPFFES
RVDNKERTIISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEVKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPPKTYENFIHLIIALPVAVLLIVGGLVIMLYVFHRK
RSNSRLGNGVLYASVNPEYFSAADVYIPDEWEVAREKITMSRELGQGSFGMVYEGVAKGV
VKDEPETRVAVKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMEL
MTRGDLKSYLRSLRPETENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNC
MVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVV
LWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQFNPKMRPAFLE
IISSIKDEMEPSFQEVSFYYSDENKPPEPEELDLEPENMESVPLDPSASSASLPLPDRHA
GHKAENGPGPRMLVLRASFDERRPYAHMNGGRKNERALPLPQSSTC
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgaagtccggttccggaggagggtccccgacctcgctgtgggggctcctgtttctctcc
gccacgctcttgctctggccgacgagtggagaaatctgtgggccgggcatcgacatccgc
aacgactatcaacagttgaagcgcctggagaactgcacggtgattgagggctacctccac
atactgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgaatacctgctgctgttccgcgtggccggcctcgagagccttggagacctcttc
cccaaccttacggtcatccgtggctggaagctcttctacaactatgccctggtcatcttc
gagatgaccaatctcaaggatattgggctttacaacctgaggaacattactcggggggcc
atcaggattgagaaaaatgctgacctgtgttacctctccactgtggactggtccctgatc
ctggacgcggtgtccaataactacattgtggggaacaagccccccaaggagtgtggggac
ctgtgtccaggagccatggaagagaagccactgtgcgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccccaaatcactgccagaaaatgtgcccgagcacgtgcggg
aagcgggcgtgcacagagaacaacgagtgctgccactctgagtgcctgggcagctgcagc
acacccgacaatgacacggcctgcgtggcctgccgccactactatcacgccggtgcctgt
gtgcctagctgcccgcccaacacctacaggtttgagggctggcgctgtgtggaccgcgac
ttctgtgccaacatccccagtgccgagagcagcgactccgagggctttgtcatccacgac
ggcgaatgcatgcaggagtgcccctcgggcttcatccgcaatggcagcgaaagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacttctgctcaaatgctccaaggatgtaccatcttcaagggcaacttg
ctcattaatatccgacgaggcaataacattgcctcggaactggagaacttcatgggactt
attgaggtggtgacgggctacgtgaagatccgccattcccacgccttggtttccttgtcc
ttcctaaaaaaccttcgccagatcttaggagaggagcaactggaagggaattattccttc
tatgtccttgacaaccagaacttgcagcagctgtgggactgggaccaccacaacctgacc
atcaaagctgggaaaatgtactttgctttcaatcccaaattgtgtgtttccgaaatttac
cgcatggaggaagtgacggggactaaagggcgccagagcaaaggggacatcaacaccagg
aataatggagaaagagcctcctgtgaaagtgacgtcctgcacttcacctccaccaccacg
tggaagaatcgcattatcataacctggcaccgataccggccccctgactacagggatctc
atcagcttcaccgtttactacaaggaagcaccctttaaaaatgtcacagagtatgatgga
caggatgcctgtggctccaacagctggaacatggtggatgtggacctcccttccaacaag
gatatagaacctggcattctcctgcacgggctgaagccctggactcagtatgccatttac
gtcaaggctgtgaccctcactatggtggagaacgaccatatccatggggccaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggacgttctttctgcg
tcaaactcctcttctcagttaattgtgaagtggaaccccccctctctgcccaacggtaac
ctgagctattacatcgtgagatggcagcagcagcctcaggatggctacctttaccggcac
aattactgctctaaagacaaaatccccatcaggaagtacgctgatggcaccattgacatc
gaagaggtgacagagaatcccaagactgaagtgtgtggtggagagaaagggccttgttgc
gcttgccccaaaaccgaagccgagaagcaggcggagaaagaggaggctgagtaccgcaaa
gtcttcgagaatttcctgcacaactccatcttcgtgcccagacctgaaaggaagcggaga
gatgtcatgcaagtggccaacaccaccatgtccagccgaagcaggaacaccacggtggca
gatgcctacaatattacagacccagaagagctagagacagagtaccctttctttgagagc
agagtggataacaaggagagaacaatcatctctaacctccggccttttaccttgtaccgc
attgatatccacagctgtaaccatgaggctgagaagctgggctgcagcgcctccaacttt
gtctttgcaagaaccatgcccgcggaaggagcagatgacattcctgggccagtgacctgg
gagccaaggcctgagaactccatcttcttaaagtggccagaacccgagaatcccaatgga
ttgattttaatgtatgaagtaaagtatggatcgcaaattgaggatcagcgggaatgtgtg
tccaggcaggaatacaggaagtatggaggggccaagcttaaccggctaaacccagggaac
tatacggcccggattcaggccacctctctctctgggaatggatcttggacggaccccgtg
ttcttctatgtcccacctaagacttatgaaaacttcatccatctgatcattgctctgccc
gttgccgtcctgttgatcgtgggagggttggtgataatgttgtacgtcttccacagaaag
agaagtaacagcagactggggaatggagtgctgtacgcctctgtgaaccccgagtacttc
agcgcagccgatgtgtacattcctgacgagtgggaggtggctcgagaaaagatcaccatg
agccgagagcttggccaggggtcgttcgggatggtctatgaaggggttgccaagggcgtg
gttaaagatgaacccgagaccagggtggctgttaaaactgtgaatgaggctgccagcatg
cgcgaaaggattgagtttctcaacgaggcttctgtgatgaaggagttcaattgtcaccat
gtggtgcgcttgctgggcgtggtgtcccaaggccagccaacgctggtcatcatggaactg
atgacccggggggatctcaaaagttatctcaggtctctgaggccagaaacggagaataat
ccagtcctagcacctccaagcctaagcaagatgatccaaatggccggagagattgcagac
ggcatggcatacctcaatgccaacaagttcgtccacagagacctcgctgcccggaattgc
atggtggctgaagatttcacagtcaaaattggagattttggaatgacacgagatatctat
gagacagactattaccggaaaggagggaaagggttgctgcccgtgcgctggatgtcccct
gagtcccttaaggatggagtcttcaccactcattcagacgtctggtcctttggagttgtc
ctctgggagattgccacgctggccgagcagccataccagggcttgtccaatgagcaggtc
cttcgcttcgtcatggagggtggccttctggacaagccggacaactgccccgacatgcta
tttgagctgatgcgcatgtgctggcagttcaaccccaagatgaggcctgccttcttggag
atcataagcagcatcaaagatgagatggaacccagctttcaggaggtctccttctactac
agcgacgagaacaagccacccgagccagaggagctggacctggagccggagaacatggag
agcgtccccctggacccttcagcctcctcggcctccctgccgctgcctgacagacacgca
ggacacaaggccgagaacggcccgggccctaggatgctggtcctgcgtgccagcttcgat
gagagacggccttacgcacacatgaacgggggccgcaagaatgagagggccttgccgctg
ccccagtcttcaacctgctga
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integrated database retrieval system
