Heterocephalus glaber (naked mole-rat): 101697591
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Entry
101697591 CDS
T02812
Symbol
Sdha
Name
(RefSeq) succinate dehydrogenase complex flavoprotein subunit A
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00020
Citrate cycle (TCA cycle)
hgl00190
Oxidative phosphorylation
hgl01100
Metabolic pathways
hgl01200
Carbon metabolism
hgl04714
Thermogenesis
hgl04932
Non-alcoholic fatty liver disease
hgl05010
Alzheimer disease
hgl05012
Parkinson disease
hgl05014
Amyotrophic lateral sclerosis
hgl05016
Huntington disease
hgl05020
Prion disease
hgl05022
Pathways of neurodegeneration - multiple diseases
hgl05208
Chemical carcinogenesis - reactive oxygen species
hgl05415
Diabetic cardiomyopathy
Module
hgl_M00009
Citrate cycle (TCA cycle, Krebs cycle)
hgl_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
hgl_M00148
Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
101697591 (Sdha)
09102 Energy metabolism
00190 Oxidative phosphorylation
101697591 (Sdha)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
101697591 (Sdha)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
101697591 (Sdha)
09164 Neurodegenerative disease
05010 Alzheimer disease
101697591 (Sdha)
05012 Parkinson disease
101697591 (Sdha)
05014 Amyotrophic lateral sclerosis
101697591 (Sdha)
05016 Huntington disease
101697591 (Sdha)
05020 Prion disease
101697591 (Sdha)
05022 Pathways of neurodegeneration - multiple diseases
101697591 (Sdha)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101697591 (Sdha)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101697591 (Sdha)
Enzymes [BR:
hgl01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
101697591 (Sdha)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Thi4
Pyr_redox_2
GIDA
DAO
FAD_binding_3
HI0933_like
Motif
Other DBs
NCBI-GeneID:
101697591
NCBI-ProteinID:
XP_004845158
UniProt:
G5BPG8
LinkDB
All DBs
Position
Un
AA seq
665 aa
AA seq
DB search
MAGVGTVSRFLRARRLALSRAQWPAAFRAQACGFHFSVNGNKRASAKVSNSISTQYPVVD
HEFDAVVVGAGGAGLRAAFGLSEAGFNTACLTKLFPTRSHTVAAQGGINAALGNMEEDNW
RWHFYDTVKGSDWLGDQDAIHYMTEQAPASVIELENYGMPFSRTEDGRIYQRAFGGQSLK
FGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMEDGECRGVIALCI
EDGSIHRLRAKNTVVATGGYGRTYFSCTSAHTTTGDGTAMITRAGLPCQDLEFVQFHPTG
IYGAGCLITEGCRGEGGILINSEGERFMERYAPVAKDLASRDIVCRSMTLEIREGRGCGP
EKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYRG
QVLKHVNGQDQVVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESSRPGD
KVPPVKPNAGEESVTNLDKLRFADGSIRTSELRLNMQKTMQNHAAVFRVGSVLQEGCEKI
SQLYGDLKHLKTFDRGMVWNTDLVETLELQNLLLCALQTIYGAEARKESRGAHAREDYKV
RIDEFDYSKPIQGQQKRPFGEHWRKHTLSYVDIKTGKVTLEYRPVIDKTLNEADCSTVPP
AIRSY
NT seq
1998 nt
NT seq
+upstream
nt +downstream
nt
atggcgggggtcgggaccgtttcgcggtttcttcgcgcgcggcgcttggcgctgtcccga
gcgcagtggccagcagccttccgagcacaggcctgtggctttcacttcagtgtcaacggg
aataagagggcatctgctaaagtttcaaattcaatttcaactcagtacccagtagtggat
cacgaatttgatgcagttgtggtaggcgctggaggggcaggtttgcgagctgcatttggc
ctttctgaggcaggctttaataccgcatgccttacaaagctttttcctactcggtcacac
actgttgcagcacagggaggaatcaatgctgctttggggaacatggaagaggacaactgg
agatggcacttctatgacactgtgaagggctctgactggctgggggaccaggatgccatc
cattacatgacagagcaggcccctgcctccgtgattgagctagaaaattatggcatgcca
tttagcagaaccgaagatgggaggatttaccagcgtgcatttggtgggcagagcctcaag
tttgggaaaggcgggcaggcccaccggtgctgctgtgtggctgatcggactggccactca
ctcctgcacaccttgtatggaaggtctctgcgatacgataccagctattttgtagagtat
tttgccttggatctcttgatggaagatggggaatgtcgtggtgtgattgcactgtgcata
gaagatgggtccatacatcgcctaagagcaaagaacactgttgttgctactggaggctat
gggcggacctacttcagctgcacctctgcccacaccaccactggtgatggcacagccatg
attaccagagctggccttccctgccaggacttggagtttgtgcagttccaccccacaggc
atatatggtgctggttgtctcatcacagaaggatgccgtggagaaggaggcattctcatt
aacagtgagggtgagaggttcatggagagatatgcccccgtcgcgaaggacctggcatcc
cgagatattgtatgtcggtccatgactctggagatccgtgaaggaagaggctgtggccct
gagaaagatcatgtctacctgcagctacaccatctgccccctgagcagctggccacccgc
ttgcctggcatctcagagacagccatgatctttgctggcgtggatgtcaccaaggagcca
atccctgtcctccccaccgtgcattacaacatgggtgggattcccaccaactacaggggg
caggtgctgaagcatgttaatggccaggatcaggttgtgcctggcctctatgcctgtggg
gaggctgcctgtgcctcagtgcatggtgccaacaggcttggggcaaactcccttctggac
ctggtagtctttggacgggcctgtgccctaagcattgcagagtcttccagaccaggagat
aaagttcctccagttaaaccaaatgccggggaagagtctgtcactaatcttgacaagttg
agatttgctgatggaagcataagaacatcagaactgcgtctcaacatgcaaaagacaatg
cagaatcatgctgcagtattccgtgtgggaagcgtgctgcaagaaggctgtgagaaaatc
agccagctctatggagacctgaagcacctgaagacgtttgacagaggaatggtctggaac
acagacctggtggagaccctggagctgcagaacctgttgctctgtgcacttcagaccatc
tatggagcagaggcacggaaggagtcacggggtgcccatgccagggaagattacaaggtg
cggattgatgagtttgattactccaagcccatccaggggcagcagaagaggccatttggg
gagcactggaggaagcacaccctttcctatgtggacatcaagactgggaaggtcaccctg
gaatataggcctgtcatcgacaagaccttaaatgaggctgactgctccacggttccccct
gccattcgctcctactga
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