Heterocephalus glaber (naked mole-rat): 101701152 Help Entry 101701152         CDS       T02812                                  Symbol Xrn1 Name (RefSeq) 5'-3' exoribonuclease 1   KO K12618   5'-3' exoribonuclease 1 [EC:3.1.13.-] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl03008   Ribosome biogenesis in eukaryotes hgl03018   RNA degradation Brite KEGG Orthology (KO) [BR:hgl00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     101701152 (Xrn1)   09123 Folding, sorting and degradation    03018 RNA degradation     101701152 (Xrn1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:hgl03019]     101701152 (Xrn1)    03009 Ribosome biogenesis [BR:hgl03009]     101701152 (Xrn1)    03016 Transfer RNA biogenesis [BR:hgl03016]     101701152 (Xrn1)    03036 Chromosome and associated proteins [BR:hgl03036]     101701152 (Xrn1) Messenger RNA biogenesis [BR:hgl03019]  Eukaryotic type   mRNA surveillance and transport factors    mRNA cycle factors     Common to processing body (P body) and stress granule      101701152 (Xrn1)   mRNA degradation factors    5'-3' decay     5' exonucleases      101701152 (Xrn1) Ribosome biogenesis [BR:hgl03009]  Eukaryotic type   Pre-60S particles    RNases     101701152 (Xrn1) Transfer RNA biogenesis [BR:hgl03016]  Eukaryotic type   tRNA degradation factors    Rapid tRNA decay (RTD) pathway factors     101701152 (Xrn1) Chromosome and associated proteins [BR:hgl03036]  Eukaryotic type   Gene silencing    piRNA pathway     101701152 (Xrn1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  XRN_N XRN_M XRN1_D2_D3 XRN1_D1 SH3_12 Dicer_dimer Motif Other DBs NCBI-GeneID:  101701152 NCBI-ProteinID:  XP_004834433 LinkDB All DBs Position Un AA seq 1734 aa AA seqDB search MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE TLPTEARFDSNCITPGTEFMARLHEHLKYFVNVKISTDKSWQGVTIYFSGHETPGEGEHK IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA PEETTFHLLHLSLMREYIDYEFSVLKENITFKYDIERIIDDWILMGFLVGNDFIPHLPHL HINHDALPLLYGTYITILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW FESKVGNKYLNEAAGIAAEEAKNYKEKKKSKGQENSVCWAALDKSEGEMVVSKDNLEDET EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAVCYVQAIQWILHYYYHGVQSWSWY YPYHYAPFLSDIRNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPVCYQHLMTSEDSP IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKEEERKRNRHSECLM CWYDKDTEFIYPSPWPEKFPAIERCYTRYKIISLDAWHVDISKNKITRVDQKALYFCGFP TLKHIKHKFFLKKSGVQVFQQSSRGENMMLEILVNAESDELSIENVASSVLGKSVFVNWP HLEEARVVAVSDGETKFYLEEPPGTQKLYLGRTAPPSKVIHLGDKEQSNWTKEVQGISEH YLRRKGIIINETSMVVYAQLLTGRKYQINHNGEVRLEKQWSKQILPFVYQTIVKDIQAFD SRFSSIKTLDDLFPPGSVVFMLGTPYYGCTGEVQVSGDVITEGRIRVVFSIPCEPNLDAL IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVDKCKQRKNNKKVRVTV KPHLLYRPLEQQHGVIPDRDAEFRLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF EVLFDEEFPGGLTIRCSPGKGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVNQYSS NSSVSPGHLGGLNHSSQSLFVPTQVSTKADDEFCNIWQSLQGSRKIQHFQPSIQEKGPVL PQEISQVIQQHKSGFYDNSVKYQQRKHEPHRKFKEECKSPKAECRSQKMSSKQAFGGSAK CNIKLLKRNERPEVSEIQKAVTGYPNATDKPNSGIENFLASLNISKENELPSSHHGEPPN EEHLSPQSFAMKGTRMLKEILKIDGSDTVDPKNEMKRYGNEVTVSSNRRDEYGLSSQPKQ NKKLAPYMNKLHRANEYHSIPSVDSTCWPIPSQVSSVSTPVTELARICSLVGMPQPDFSF LRTPQTMTVCQVKLSNGLLVHGPQCRSENEAKEKAALFALQQLGSLGVNFPLPPPLFPNY PPAIPPGTIPPVFPQPPANIMPSSPRLFGSVPWGPPLPVPGKPFHQTLYPGAVPTAGGIM PGGAHNQFIPLQVMKKRVANKKNFENKETQSSSQATPTQTSKPGSSDIAKVTAQESSSAP LNSSQVAQAASSFQGETASHGSHNAPHQKAAPSSSSRRRSRKLAVNFGVSKPSE NT seq 5205 nt NT seq  +upstreamnt  +downstreamnt atgggagtccccaagttttaccggtggatctcggagcggtatccttgcctcagcgaagta gtgaaagagcatcagattcctgaatttgacaacttgtacctggatatgaatggaattata catcagtgctctcatcctaatgatgatgatgtccactttagaatttcagatgacaaaatc tttactgacatttttcactacttggaggtgttgtttcgcattattaaacctaggaaagtg ttctttatggctgttgatggtgtagctcctcgagcaaaaatgaatcaacagcgtgggagg cgttttaggtcagccaaggaggcagaagacaaaattaaaaaggcaattgaaaagggggaa actcttcctacagaggccaggtttgattccaactgtattacaccagggactgaattcatg gccaggttacatgaacatctgaagtattttgtaaatgtgaaaatttccacagacaagtca tggcaaggagttaccatctacttctcaggccatgagactcccggagaaggagaacataaa atcatggaatttatcagatctgaaaaagcaaagccagatcatgacccaaacaccagacac tgtctttatggtctagatgctgacttgatcatgcttggattaacaagtcacgaggcacat ttttctcttttaagagaagaagttcgatttggtggcaaaaaaacacagagggtgtgtgca ccagaagaaaccacatttcacctcctacatttgtcattaatgagagagtatattgactac gagttttcagtattaaaagaaaatattacatttaaatatgatattgaaagaattatagat gattggattttgatgggatttcttgttggcaatgattttatccctcatctacctcattta catattaatcatgatgcgctgcctcttctttatggaacatatattaccatcctgcccgaa cttggaggttatattaatgaaagtggacatctcaatttacctcgatttgaaaaatacctt gtgaaactatctgattttgatcgggagcacttcagtgaagtttttgtggacctaaagtgg tttgaaagcaaagttggtaacaagtatctcaatgaagcagcaggtatcgcagctgaagaa gccaagaactacaaggaaaagaaaaaatcaaagggccaggaaaattctgtatgttgggct gctttagacaaaagtgaaggtgaaatggtagtttctaaggataatttagaagatgagact gaagatgatgatctatttgaaaccgagtttagacaatacaaaagaacatattacatgacg aagatgggggttgatgtggtatctgatgactttctggctgatcaagctgtatgttatgtt caagcgatacagtggattttgcactattactatcatggtgttcagtcctggagttggtat tatccctatcattatgcacctttcctatctgatatccgaaatatcagtacactcaaaatc cattttgaactaggaaaaccttttaagccatttgagcagcttcttgctgtacttccagca gctagcaaaaatttgcttcctgtatgctaccagcatttgatgaccagtgaagactcaccg attatagagtattatccacctgattttaaaactgatctaaatggaaaacaacaggaatgg gaagctgttgtattaataccttttattgatgagaagcgattgttggaagccatggagaca tgtaaccactccctcaaagaggaagagaggaagagaaaccgacatagtgagtgcctgatg tgctggtatgataaagacacagagtttatctacccttctccatggccagaaaaattccct gccatagaacgatgctatacacggtacaaaataatatcactagatgcttggcatgtagat ataagtaagaacaaaataaccagagttgaccagaaggcattgtatttctgtggattccct actttgaaacacatcaaacataaattttttttgaagaaaagtggtgttcaagtattccag caaagcagtcgtggagaaaacatgatgttggaaatcttagtgaatgcagaatctgatgaa cttagtatagaaaatgtagcttcatcagtgcttggaaagtctgtctttgttaattggcct caccttgaagaagctagagttgttgctgtatcagatggtgaaactaaattttacttggaa gaacctccaggaacacagaagctttatttgggaagaactgctccaccatctaaagtgata catcttggcgataaagagcaatctaattggacaaaagaggtacaaggaatatcagaacac tacttgagaagaaaaggaataataataaatgaaacatctatggttgtatatgctcagtta ctcacaggtcgtaaatatcagataaatcataatggtgaagttcgtctggaaaagcagtgg tcaaaacaaattcttccttttgtctatcaaaccattgtcaaagacatccaagctttcgac tctcgtttctccagtatcaaaacattggatgatttgtttcctcctggaagtgtggtgttt atgctggggactccttattatggctgcacaggagaagttcaagtttcaggtgatgtgatc acagaaggcagaattcgtgtggttttcagcattccatgtgaacccaatcttgatgcttta atacagaaccagcataaatattctataaagtacaacccaggatatgtattggccagtcgc cttggagtgagtggataccttgtttcaaggtttacaggaagtatttttattggaagagga tctaggagaaaccctcatggagaccataaagcaaatgtgggtttaaatctcaaattcaac aaaaaaaatgaggaggtacctggatatactaagaaagttggaagtgaatggatgtactca tctgcagcagaacaacttcttgcagaatatttagagagagctccagaactgtttagttat atagccaaaaatagccaagaggatgtgttctatgaagatgacatttggcctggagaaaat gagaatggtgctgagaaagttcaagaaattattacttggctaaaaggacatcctgtcagt actttgtctcgttcatcttgtgatttacaaattctggatgcagctattgttgagaaaatt gaggaagaagttgataaatgcaagcaaagaaaaaataacaagaaagtacgggtgacagta aagccccacttgctgtacagacctttagaacaacaacatggagtcattcctgatcgagat gcagaatttcgtctctttgaccgtgtagtgaacgtgagagagaatttttcagttccagtt ggccttcggggcaccatcataggaattaaaggggctaatagagaagctgatgtactattt gaagtattgtttgatgaagaatttcctggaggattaacaataaggtgctcacctggaaaa ggttatcgattgccaacaagtgccttagtgaacctttctcatggaagtcgctcggaaact ggaaatcagaagttgacagccattgtgaaaccacagccagctgtaaatcaatatagctca aattcatcagtttctcctggccatctcggaggcctcaaccattcctctcaatcacttttt gttcctactcaagtatctactaaagctgatgatgaattttgcaacatttggcaatcctta caagggtccagaaaaattcagcactttcagccatctatacaagagaagggtccagttcta cctcaagaaataagtcaagtaattcaacagcataaatctggcttttatgacaacagtgtt aagtatcagcaaagaaaacatgaacctcaccgaaaatttaaagaagagtgtaagagtcct aaagctgagtgtcggtcacaaaaaatgtccagtaagcaggcttttggagggtctgccaaa tgtaatattaagttactgaagagaaatgaacgtcctgaagtctcagaaatccaaaaggct gtgactggttacccaaatgctactgataagcctaactctggaattgagaactttttagca tccttgaatatctctaaagaaaatgaattaccatcatctcatcatggagagcctccaaat gaagagcatttgtctccacagtcatttgctatgaagggaacacgaatgcttaaagaaatt ctaaaaattgatggttctgacacagtggaccctaagaatgaaatgaaacgatatggaaat gaagttactgtttcttctaatagaagagatgaatatggactatcctcacagcctaaacaa aataagaaattagcgccttatatgaacaagcttcaccgtgccaatgaataccacagtatt ccgtctgtggacagtacgtgctggcctattcccagccaggtctcttctgtgtccacacca gtaactgaacttgctcgaatttgttcccttgttgggatgccacaaccagatttctccttt ctgagaacacctcagacaatgacagtttgccaggtaaaattatcaaatggtttactggtg catgggccacagtgccgctctgaaaatgaagccaaggagaaagctgcactttttgcttta caacaactgggctccttaggagtgaattttcctttgcctccaccactatttccaaattat cctcctgctataccacctggaaccattcctccagtttttccccaacctcctgctaatata atgccttcatcacctcgtctctttggctcagttccgtggggtccaccattgccagttcct ggaaagcccttccatcagactctgtaccctggggctgtgcccacagctggaggaataatg ccaggtggtgcgcacaatcagttcatacctttgcaggtcatgaaaaaaagagttgcaaac aaaaagaactttgagaataaagaaacccagagctcttctcaagccaccccaacacagact agcaagccagggtcttctgatattgccaaagtgactgcacaggaaagttcatcagcccct ttgaactcctctcaggttgctcaggctgcatcttcttttcaaggtgaaactgcctcccac ggcagccataatgcacctcaccagaaggcagcaccaagctcttcttcaagaagaagatca aggaaactggctgtcaattttggcgtttctaaaccttctgaataa

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