Heterocephalus glaber (naked mole-rat): 101706410 Help Entry 101706410         CDS       T02812                                  Symbol Hk3 Name (RefSeq) hexokinase 3   KO K00844   hexokinase [EC:2.7.1.1] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00010   Glycolysis / Gluconeogenesis hgl00051   Fructose and mannose metabolism hgl00052   Galactose metabolism hgl00500   Starch and sucrose metabolism hgl00520   Amino sugar and nucleotide sugar metabolism hgl00524   Neomycin, kanamycin and gentamicin biosynthesis hgl01100   Metabolic pathways hgl01200   Carbon metabolism hgl01250   Biosynthesis of nucleotide sugars hgl04066   HIF-1 signaling pathway hgl04910   Insulin signaling pathway hgl04930   Type II diabetes mellitus hgl04973   Carbohydrate digestion and absorption hgl05230   Central carbon metabolism in cancer Module hgl_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate hgl_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose hgl_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     101706410 (Hk3)    00051 Fructose and mannose metabolism     101706410 (Hk3)    00052 Galactose metabolism     101706410 (Hk3)    00500 Starch and sucrose metabolism     101706410 (Hk3)    00520 Amino sugar and nucleotide sugar metabolism     101706410 (Hk3)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     101706410 (Hk3)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     101706410 (Hk3)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101706410 (Hk3)   09154 Digestive system    04973 Carbohydrate digestion and absorption     101706410 (Hk3)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     101706410 (Hk3)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101706410 (Hk3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hgl04131]     101706410 (Hk3) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      101706410 (Hk3) Membrane trafficking [BR:hgl04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     101706410 (Hk3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  101706410 NCBI-ProteinID:  XP_004836371 LinkDB All DBs Position Un AA seq 969 aa AA seqDB search MLHLPGGQTPLWNHMDSVEPAGLQPGKRASGCPQKGLFQPSDSSELVQECLQQFKVTRTQ LQQIQASLLDSMEQALTGEASPAPGVRMLPTYVGSTPHGNEQGNFVVLELGASGASLRVL WVTLTGIKGQRVEPKSQEFVIPQEVVLGTGQQLFDFAAHCLFEFLGAHSVGNQGLQLGFS FSFPCHQTGLDRVRWRGNRDSGWRGNAAPMKAFGSVTQLFCPQSTLISWTKGFRCSGVEG QDVVQLLRDAIQRQGAYSIDVVAVVNDTVGTMMGCEPGVGSCEVGLVIDTGTNVCYMEEA RHVAMLDEDRGRTCISVEWGSFNDDGALGPVLTTFDHALDHASLNPGAQRFEKMIGGLYL GELVRLVLAHLAQHRVLFGGYTSPALLSQGSILLEHVAEMEDPTTGAARVHTILQELGLS PEASDAELVQRVCAAVCSRAAQLCAAALAAILSRLQRSREQQILQVTVATGGQVLERHPR FRGILQETVKLLASECNVSFIPSVDGGGRGVAMVTAVAARLAAHRRLLEETLAPFRLSHE QLATVQTQMREAMAKGLRREASSLRMLPTYVRATPDGSERGDFLALDLGGTNFRVLLVRV AEGGVQIVNQVYSIPECVAQGSGQQLFDHIVDCIVDFQQKQGLRGQSLPLGFTFSFPCKQ LGLDQGILLNWTKGFNASGCEGQDVVYLLREAIKRRQAVELNVVAIVNDTVGTMMSCGYE DPRCEMGLIVGTGTNACYMEELQNVAGVAGDSGHMCINMEWGAFGDDGSLGMLSTCFDVR VDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFQGQQTQRLQTRDIFKTKFLS EIESDSLALRQVRAILEDLGLSLTSDDALIVLEVCQAVSRRAAQLCGAGVAAVVEKIREN RGLEELTVSVGVDGTLYKVHPHFANLVAATVRELAPRCVVTFLQSEDGSGKGAALVTAVA CRLAQMACV NT seq 2910 nt NT seq  +upstreamnt  +downstreamnt atgctgcatctcccaggtggccagactccattgtggaaccatatggactccgtagagcct gccgggttgcaacctgggaaaagagcttcaggctgtccccagaagggcttatttcagccc tcagacagctcagagctggtacaggagtgtctgcagcaattcaaggtgacaaggacacag ctacagcagatccaagccagcctcttagactccatggagcaggccctgacaggagaggcc agccctgcccctggtgtccggatgctgcctacatatgtggggtctacccctcatggcaat gagcaaggaaacttcgtggtgctggagctgggggcttcaggagcatcactgcgtgtcttg tgggtgactctgacgggcatcaaggggcagagggtggagcccaagagccaggagtttgtg atcccccaggaggtggtactgggcactggccagcagctctttgactttgctgctcactgc ctttttgagttcctgggtgcacactctgtggggaatcagggtctgcagcttggattcagc ttctccttcccttgtcaccagacgggactggacagggtgaggtggaggggcaatagggac agtgggtggagagggaatgcagcccctatgaaggcctttggaagcgtaacccagcttttt tgcccccagagcaccctcatttcttggaccaaaggttttaggtgcagtggtgtagaaggc caggatgtggtccaattgctgagagatgccattcagaggcagggggcctacagcattgat gtggttgctgtggtgaatgatacagtgggcacgatgatgggctgcgagccaggtgttggg tcatgtgaagttggccttgtcatagacactggcaccaatgtgtgttacatggaggaggca cggcatgtggcaatgctagacgaggaccggggccgcacctgcatcagcgttgaatggggc tccttcaatgatgatggggctctggggccagtgctgaccacctttgaccatgccctggac catgcatccctgaatcctggtgcccagaggtttgagaagatgatcgggggcttgtacctg ggggaactggtgcggctggtgctggcccatttggcccagcacagggtcctgtttggtggc tacacctctcctgctttgctgagccaaggcagcatcctcctggaacacgtggctgagatg gaggaccccaccactggggcagcccgtgtccacacaatcctgcaggagttgggcctgagc ccggaggcctcagatgctgagcttgtgcagcgcgtctgtgcagccgtgtgctctcgggct gcccagctctgtgctgctgccctggccgccatcctgtcccgcctccagcgcagccgggag cagcagatactccaggtcaccgtggctactggaggccaagtgcttgaacggcaccccagg ttccgcggcatcctacaggagacagtgaagctcttggcttcagaatgtaatgtctccttc atcccttctgtggatggaggtggccggggtgtggcaatggtgacagctgtggctgcccgc ctggctgcccaccgacgactgctggaggagaccctagcaccattccggttgagccatgag cagctggcaacagtgcagacacagatgcgggaggccatggccaagggcctgcgaagggag gcctcctctctccgaatgctgcccacatacgtacgggctacacctgatggcagtgaacga ggggacttcctggctttggaccttgggggcaccaactttcgggtcctcctggtgcgtgtg gccgagggaggtgtgcagatcgtcaaccaggtctactccatccctgagtgtgtggctcag gggtctgggcagcagcttttcgaccacatcgtggactgcattgtggacttccagcagaag cagggcctgaggggacagagcctccccctgggtttcaccttttccttcccatgcaagcag cttggcctggaccagggcatcctcctgaactggactaagggtttcaacgcatcaggttgc gagggccaggatgttgtgtatctgttgcgggaagccatcaagcgtagacaggcagtggag ctgaatgtggttgccattgtcaatgacacagttgggaccatgatgtcctgtggctatgag gatccccgttgcgagatgggcctcattgttggaactggtaccaatgcctgctacatggaa gagctccagaatgtggcaggtgtggcgggggactcaggccacatgtgcatcaacatggag tggggtgcctttggggatgatggctctttgggcatgctcagcacctgttttgatgtgagg gtggaccaggcatccatcaatcctggcaagcagaggtttgagaagatgatcagtgggatg tacttgggagagattgtccgccacatcctcttacatttgaccagccttggagttctcttc cagggccagcagacccagcgccttcagactagggacatcttcaagaccaagtttctctct gagattgaaagcgacagcctggccctgcgacaggtccgagccatcctggaggatctgggg ctgtccctgacctcggatgatgccctgatagtcctagaggtgtgccaggctgtgtcccgg agggctgcccaactctgcggggcaggtgtggctgctgttgttgagaagatccgggagaac cggggcctggaggagctgacggtgtctgtgggggtggatgggaccctctacaaggtgcac cctcactttgccaatcttgtggctgccacagtacgggaactggcccctcgctgtgtggtc accttcttgcagtcagaagatgggtctggcaaaggtgcagctttggtcactgctgtcgcc tgtcgccttgctcagatggcctgtgtctga

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