Heterocephalus glaber (naked mole-rat): 101708521 Help Entry 101708521         CDS       T02812                                  Symbol Hkdc1 Name (RefSeq) hexokinase domain containing 1   KO K00844   hexokinase [EC:2.7.1.1] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00010   Glycolysis / Gluconeogenesis hgl00051   Fructose and mannose metabolism hgl00052   Galactose metabolism hgl00500   Starch and sucrose metabolism hgl00520   Amino sugar and nucleotide sugar metabolism hgl00524   Neomycin, kanamycin and gentamicin biosynthesis hgl01100   Metabolic pathways hgl01200   Carbon metabolism hgl01250   Biosynthesis of nucleotide sugars hgl04066   HIF-1 signaling pathway hgl04910   Insulin signaling pathway hgl04930   Type II diabetes mellitus hgl04973   Carbohydrate digestion and absorption hgl05230   Central carbon metabolism in cancer Module hgl_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate hgl_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose hgl_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     101708521 (Hkdc1)    00051 Fructose and mannose metabolism     101708521 (Hkdc1)    00052 Galactose metabolism     101708521 (Hkdc1)    00500 Starch and sucrose metabolism     101708521 (Hkdc1)    00520 Amino sugar and nucleotide sugar metabolism     101708521 (Hkdc1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     101708521 (Hkdc1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     101708521 (Hkdc1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101708521 (Hkdc1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     101708521 (Hkdc1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     101708521 (Hkdc1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101708521 (Hkdc1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hgl04131]     101708521 (Hkdc1) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      101708521 (Hkdc1) Membrane trafficking [BR:hgl04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     101708521 (Hkdc1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  101708521 NCBI-ProteinID:  XP_004846239 LinkDB All DBs Position Un AA seq 917 aa AA seqDB search MFAVHLVAFYFTKLKEDQIKKVDRFLYHMRLSDETLLDIMARFQAEMEKGLGKDTNPTAS VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVSEEGKRNVQMESQFYPTPNEIIR GNGTELFEYVADCLADFVRTKGLQHKKLPLGFTFSFPCRQTKLEEGVLLSWTKKFKARGV QETDIVSRLTKAMRKHKDLDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL YLGELVRLILLNMAKAGLLFGGVKSSTLLTKGKIETQHVAAMEKYKEGLANTREILVDLG LEPSEADCIAVQHVCTIVSFRSANLCASALAAILTRLRENKKLARLRTTVGMDGTLYKIH PQYPKRLHKVVRKLVPNCDVRFLLSESGSTKGAAMVTAVACRVQAQRKQIDEVLALFQLT RQQLVDVQGKMRAELEYGLKRKTHALATVKMLPTYVYGMPDGTEKGKYLALDLGGTNFRV LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFT FSFPCRQANIDKGTLIEWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT MMTCAYEDPNCEIGLIAGTGSNMCYMEEMRNIELVEGNEGKMCINTEWGGFGDNGCIDDI RTQYDMEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGRISERLRTRGI FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI VEKRRQDQRLEHLKITVGVDGTLYKLHPHFSLVLQETVKELAPQCDVMFLLSEDGSGKGA ALITAVAKRLQQPRREN NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgtttgcggtacacctggtggcattttacttcaccaagttgaaggaggatcagatcaag aaggtggacaggttcctgtaccacatgcggctctcagacgagacccttctggatatcatg gcgaggttccaggccgagatggagaagggactggggaaggacaccaaccccacagcctct gtgaagatgctgcccaccttcgtcagggccattccggatggctcagaaaatggggagttc ctttccctggatcttggagggtccaagttccgggtcttgaaggtgcaagtctcagaagag gggaagcgaaacgtccagatggagagtcagttctacccaacgcccaatgaaatcatccga gggaacggcacggagctgtttgaatatgtagctgattgcctggcggatttcgtgaggacc aaagggctgcagcataagaaattaccccttggctttaccttttcttttccctgcagacag actaagttggaagagggcgtcctgctgtcatggaccaagaagttcaaggcacggggagtt caggagacagatatcgtgagtcgcctgactaaagccatgagaaaacacaaggacctggat gtggacattctggccttggtcaatgacactgtggggaccatgatgacgtgtgcctatgac gatccctactgtgaagttggcgtcatcattggaactggcaccaatgcatgctacatggag gacatgagcaacattgacctcgtggagggtgacgaggggaggatgtgcatcaacaccgag tggggggcctttggggatgacggggccttggaggacatccgcaccgagtttgacagggag ctggacctaggctcgctcaacccggggaagcaactgtttgagaagatgatcagtggcctg tacctgggggagcttgtcaggctcatcttgctgaatatggccaaggctggcctcctgttc ggtggtgtgaaatcctccactctcctcacgaagggcaagatcgaaacgcagcacgtggct gctatggagaagtataaagaaggccttgccaacacaagagagatcctggtggacctgggc ctggagccctcggaggctgactgcattgctgtccagcatgtctgcaccatcgtgtccttc cgttcggccaatctctgtgcatcggccctggcagccatcctgacacgcctccgagagaac aagaagctggctcggctccggaccaccgtgggcatggatggcacactctacaagatacac cctcagtacccaaaacgcctgcacaaggtggtgaggaagctggtcccaaactgtgacgtc cgatttctactgtcagagagtggcagcaccaagggggccgccatggtgactgctgtggcc tgccgtgtgcaggcccagcggaagcagattgatgaggtgctggctttgttccagctgacc cgacagcagcttgtggatgtgcagggcaagatgcgtgctgagcttgagtacgggctgaag aggaagacccatgccctggccacggtcaagatgctgcccacctatgtctacggcatgccg gatggcacagagaagggaaagtaccttgctctggacttgggaggaactaactttcgggtc ctcctggtgaagatcagaagtggacggaggtcagtgagaatgtacaataagatctttgcc atccctctggagatcatgcagggtactggtgaggagctgtttgatcacattgtgcagtgc attgctgacttcctggactacatgggcctcaaaggggcccagctccctttgggcttcacg ttctcctttccctgcaggcaggcgaacatcgacaagggaacactcatagagtggaccaaa ggctttaaggccaccgactgtgaaggggaggacgtggtggacatgctcagggaagccatc aagaggagaaatgagtttgacctggacatagttgcagttgtgaatgacacagtggggacc atgatgacctgtgcttatgaagatcctaattgtgagattggcctgattgcagggacagga agcaacatgtgctacatggaggagatgaggaacatcgagttggtggaagggaatgaaggg aagatgtgcatcaacactgagtggggagggtttggagataatggctgcatagacgacatc cggacccagtatgacatggaggtggatgaggggtccttgaatcctggcaaacagagatac gagaaaatgaccagtggcatgtacctgggggagattgtgcggcagatcctgattgacttg accaagcaaggtctcctcttccgagggcggatttcagagcgtctcaggaccagggggatc tttgaaaccaagttcctgtcccagatagaaagtgaccggctggccctcctccaagtcagg aggatcctgcagcagctgggtctggacagcacgtgtgaggacagcatcgtggtgaaggag gtgtgtggagctgtgtcccggcgggctgcccagctctgtggtgcaggcctggccgccatt gtggaaaaaaggagacaagaccagaggctggagcacctgaagattaccgtgggtgtggac ggcaccctgtacaagctgcaccctcacttttctctggtattgcaggaaacggtgaaagaa ttggcccctcagtgtgatgtgatgttcttgctgtcagaagacggcagcggaaagggagca gctctgatcactgcagtggccaaaaggctgcagcagccacggagggagaactag

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