Heterocephalus glaber (naked mole-rat): 101708836 Help Entry 101708836         CDS       T02812                                  Symbol Srd5a2 Name (RefSeq) steroid 5 alpha-reductase 2   KO K12344   3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00140   Steroid hormone biosynthesis hgl01100   Metabolic pathways hgl05215   Prostate cancer Module hgl_M00976   C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     101708836 (Srd5a2)  09160 Human Diseases   09162 Cancer: specific types    05215 Prostate cancer     101708836 (Srd5a2) Enzymes [BR:hgl01000]  1. Oxidoreductases   1.3  Acting on the CH-CH group of donors    1.3.1  With NAD+ or NADP+ as acceptor     1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)      101708836 (Srd5a2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Steroid_dh DUF1295 PEMT DUF6832 Motif Other DBs NCBI-GeneID:  101708836 NCBI-ProteinID:  XP_004839316 UniProt:  G5B3Y9 LinkDB All DBs Position Un AA seq 254 aa AA seqDB search MLVRCQESPVLAGSATLAILGLMILYFAQPSSYGKFSQTGAPGAQCLPARAAWFLQELPS FAVPVGILFQQPRFLVGPPETVLLGLFCAHYFHRTFIYSFLTRGRPYPAVLLFQGIVFCI GNGFLQSYYLIYCAEYPEEWFTDIRFSLGVFLFILGMGINIHSDHTLRQLRKPGEVTYRI PQGGLFTYVSGANFLGEIIEWVGYALATWSLPGLAFAFFSLCFLGLRAFYHHRFYLKMFE DYPKSRKALIPFIF NT seq 765 nt NT seq  +upstreamnt  +downstreamnt atgctagttcggtgccaggagagcccagtactggcgggcagcgccactttggccatcttg gggctaatgattctgtacttcgcgcagccctcgtcctacgggaagttcagccagacaggg gcgcccggggctcagtgcctccccgcccgcgccgcctggttcctgcaggagctgccttcc ttcgccgtcccggtagggatcctcttccagcagccccgcttcctagtcggaccgcccgag actgtgcttctggggttattctgcgcacattactttcacaggacttttatttactcattt ctcactagagggaggccttatccagcagtgctccttttccaaggaatagtcttctgcatc ggaaatggattccttcaaagctactatctgatttactgtgcagaataccctgaagagtgg ttcacagacatccggtttagcttgggtgtcttcctatttattttgggaatgggaatcaac attcatagtgaccataccttgcgccagctcagaaagcctggagaggtcacctacaggatt ccacaaggtggcttgtttacgtatgtttctggagcaaatttccttggtgagatcattgaa tgggttggctatgccttggccacttggtctcttccaggacttgcttttgcatttttctca ctttgtttccttgggcttcgagctttttaccaccacaggttctacctcaagatgtttgag gactaccctaaatctcggaaagccctcattccattcatcttttaa

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