Heterocephalus glaber (naked mole-rat): 101722401 Help Entry 101722401         CDS       T02812                                  Symbol Hk2 Name (RefSeq) hexokinase 2   KO K00844   hexokinase [EC:2.7.1.1] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00010   Glycolysis / Gluconeogenesis hgl00051   Fructose and mannose metabolism hgl00052   Galactose metabolism hgl00500   Starch and sucrose metabolism hgl00520   Amino sugar and nucleotide sugar metabolism hgl00524   Neomycin, kanamycin and gentamicin biosynthesis hgl01100   Metabolic pathways hgl01200   Carbon metabolism hgl01250   Biosynthesis of nucleotide sugars hgl04066   HIF-1 signaling pathway hgl04910   Insulin signaling pathway hgl04930   Type II diabetes mellitus hgl04973   Carbohydrate digestion and absorption hgl05230   Central carbon metabolism in cancer Module hgl_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate hgl_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose hgl_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     101722401 (Hk2)    00051 Fructose and mannose metabolism     101722401 (Hk2)    00052 Galactose metabolism     101722401 (Hk2)    00500 Starch and sucrose metabolism     101722401 (Hk2)    00520 Amino sugar and nucleotide sugar metabolism     101722401 (Hk2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     101722401 (Hk2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     101722401 (Hk2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101722401 (Hk2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     101722401 (Hk2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     101722401 (Hk2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101722401 (Hk2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hgl04131]     101722401 (Hk2) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      101722401 (Hk2) Membrane trafficking [BR:hgl04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     101722401 (Hk2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 FGGY_N Motif Other DBs NCBI-GeneID:  101722401 NCBI-ProteinID:  XP_004844710 UniProt:  G5AXE1 LinkDB All DBs Position Un AA seq 917 aa AA seqDB search MIASHLIACLFTELNRNQVQKVDQYLYHMRLSDETLLDISKRFRKEMVKGLGATTHPTAS VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEIENQIYAIPEDIMR GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV EGRDIVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGALNDIRTEFDQEIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFRGKLSPELLTTGSFETKDVSDIEEEKDGIQKAYQILVRLG MDPLQEDCVATRRVCQIVSTRSASLCAATLVAVLRRLKENKGGDRLRSTIGVDGSVYKKH PHFAKHLHKAVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEPLKLS REQLLEVKRRMKVEMERGLSKETHTIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGEELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVDGEEGRMCVNMEWGAFGDNGCLDD FRTEFDVAVDELSLNPSKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCEVSFLESEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgattgcctcgcatttgatcgcctgcctcttcacggagctcaaccgtaaccaagtgcag aaggttgaccaatatctctaccacatgcgtctctctgatgagacccttctggacatttct aagcggttccgcaaggagatggtaaaagggcttggagctaccacccatcccactgcttct gtgaaaatgctgcccacctttgtgaggtccaccccagatggaacagaacatggagagttc cttgccctggaccttggagggaccaatttccgcgtgctctgggtaaaagtaacagacaac ggactccagaaagttgagattgagaatcagatctacgccatcccggaggatatcatgcga ggcagtggcactcagctgtttgaccacattgctgaatgcctggccaacttcatggataag ctacaaatcaaagacaagaagctcccactgggctttaccttctccttcccctgccaccag actaaactagatgagagtttcctggtctcgtggaccaagggattcaaatccagtggagtg gaaggcagagacattgtggctttgatccggaaggccatccagcggagaggggactttgat attgacattgtggctgtggtgaatgacacagttgggaccatgatgacctgtggttatgat gaccagaactgtgagattggtctcattgtgggcactggcagcaatgcctgctacatggag gagatgcgccacatcgacatggtagagggcgacgagggacgaatgtgtatcaacatggag tggggggcctttggagacgatggtgcactcaatgacatccgcactgagtttgaccaagag atcgacatgggctcattgaaccctgggaagcaattgttcgagaagatgattagtgggatg tacatgggggagctggtgaggcttatcctggtgaagatggccaaggaggagctgttgttc cgggggaagctcagcccagagctccttaccacaggcagctttgagaccaaagacgtttca gatattgaagaggagaaagatggcatccagaaggcctaccagatcctggtgcggctgggc atggatcccctgcaggaagactgtgtggccacccgccgggtctgccagatcgtgtccaca cgctctgccagcctgtgtgcagccacactggttgctgtacttcggcgcctcaaggaaaac aagggcggggatcggctgcgctccaccatcggtgttgatggctctgtctacaagaagcac cctcatttcgccaagcatcttcacaaggctgtgcggaggctggtacctgactgcgacgtt cgcttcctccgctctgaggatggcagtggcaaaggggcagccatggtgactgcagtggct tatcggctggctgaccaacacagagctcgccagaagacccttgaacctctaaagctgagc cgcgagcagctgctggaggtcaagagaaggatgaaggttgaaatggagcgaggtctaagc aaggagacacataccattgcccctgtgaagatgctgcccacctatgtatgtgccactccc gatggcacagagaaaggggacttcctggctttggaccttggaggaacaaatttccgggtc ttgctggttcgtgtgcggaatgggaagcggcgaggagtggagatgcataacaagatctac tccatcccacaggaggtcatgcacggcactggggaggagctctttgaccacattgtccag tgcatcgctgacttcctggagtacatggggatgaagggtgtgtctctgcctctgggtttc accttctccttcccatgccagcagaacagcctggatgagagcattctcctcaagtggaca aaaggcttcaaggcatctggctgtgagggtgaggacgtggtcaccctgctgaaggaagca atccaccggcgagaggagtttgacctggatgtagttgcagtggtgaatgacacagtagga actatgatgacctgtggctatgaagaccctcactgtgaagttggtctcattgttggtact ggcagcaatgcctgctacatggaggagatgcgtaacgtggagctggtggacggagaagag gggcgaatgtgtgtcaacatggagtggggggccttcggggacaatggatgcttagatgac ttccgcacagaatttgatgtggctgtggatgaactctccctgaaccccagtaaacagagg tttgagaaaatgatcagtggaatgtacctgggcgagattgtccgcaacatcctcattgat ttcaccaaacgtgggctgctattccgtggccgcatctcagagcggctcaagacaagggga atctttgaaaccaagttcctgtctcagattgagagtgactgcctagccctgctgcaggtc cgtgccatcctgcaccacttggggcttgaaagcacctgtgatgacagcatcattgtcaag gaggtgtgcactgtggtggcgcggcgggctgcccagctctgtggcgcaggcatggctgcc gtggtggacaagatacgagaaaatcgtgggctggacaccctgaaagtgacagtgggtgtg gatgggaccctctacaagctacatcctcactttgccaaagtcatgcatgagacagtgaag gacttggctccaaaatgtgaagtgtccttcctggaatcggaggatggcagtgggaagggg gctgctctcatcactgccgtggcctgccgcatccgtgaggctggacagcgatag

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