Hyaena hyaena (striped hyena): 120231854
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Entry
120231854 CDS
T07257
Symbol
HTT
Name
(RefSeq) huntingtin
KO
K04533
huntingtin
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv05016
Huntington disease
hhv05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
120231854 (HTT)
05022 Pathways of neurodegeneration - multiple diseases
120231854 (HTT)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hhv03019
]
120231854 (HTT)
04131 Membrane trafficking [BR:
hhv04131
]
120231854 (HTT)
03029 Mitochondrial biogenesis [BR:
hhv03029
]
120231854 (HTT)
Messenger RNA biogenesis [BR:
hhv03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
120231854 (HTT)
Membrane trafficking [BR:
hhv04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
120231854 (HTT)
Mitochondrial biogenesis [BR:
hhv03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
120231854 (HTT)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Htt_C-HEAT
Htt_N-HEAT
Htt_bridge
Htt_N-HEAT_1
HEAT
HEAT_2
Motif
Other DBs
NCBI-GeneID:
120231854
NCBI-ProteinID:
XP_039088082
LinkDB
All DBs
Position
Unknown
AA seq
3135 aa
AA seq
DB search
MATLEKLMKAFESLKSFQQQQQQQQQQPPPPPPPQPPQPPQPLPQAQPPLPQPQPPPPPP
PLPPPGPAGAEEPLHRPKKELSATKKDRVNHCLTICENIVAQSLRNSPEFQKLLGIAMEL
FLLCSDDAESDVRMVADECLNRVIKALMDSNLPRLQLELYKEIKKNGAPRSLRAALWRFA
ELAHLVRPQKCRPYLVNLLPCLTRISKRPEESVQETLAAAVPKIMASFGNFANDNEIKVL
LKAFIANLKSSSPTVRRTAAGSAVSVCQHSRRARYFYSWLLSVLLGLLVPVEDEHSTVLI
LGVLLTLRYLVPLLQQQVKDTSLKGSFGVTRKEMEVSPSTEQLLQVYELTLHYTQHQDHN
AVTGALELLQQLFRTPPPELLQALTSPGGGQLSGAQPGPGGRSRSGSIAELLAGGGSSCS
PVLSRKQKGKVLFGEAAALEDDSESRSEGSSPAFTASVKGEIGGELAASSGVSTPGSAGS
AADSVGHDIITEQPRSQHTLQPDSVDLTGCDLASAATDGDEEDILSHSSSQISAVPSDPA
MDLNDGTQASSPVSDSSQTTTEGPDSAVTPSDSSEIVLDGADGQYPGTQVGQPQDEDEEA
AGALPEEDADAFRDSAVALQQAHLLKSMGHSRRPSDSSVDTFVSRDEAAEAGDQENKPCR
IKGDIGQSTDDDSVPLVHCVRLLSASFLLTGEKNVLVPDRDVRVSVKALALSCVGAAVAL
HPESFFSKLYKVPLDPAEYPEEQYVSDILNYIDHGDPQVRGATAVLCGTLISSILSRSHF
QVGDWMGSVRAQTGNTFSLADCIPLLRKTLKDESSVTCKLACTAVRHCVMSLCSSGSSDL
GLQLITDMLSLRDSAYWLVRTELLETLAEIDFRLVSFLEAKAENLHRGAHHYTGLLKLQD
RVLNNVVIYLLGDEDPRVRHVAAAALMRLVPKLFYKCDQGQADPVVAVARDQSSVYLKLL
MHETQPPSHFSVSTITRIYRGYNLLPSMTDVTVENNLSRVIAAVSHELVTSTTRALTFGC
CEALCLLSTAFPVCVWSLGWHCGVPPLSASDESRKSCTVGMATVVLTLLSSAWFPLDLSA
HQDALVLAGNLLAASAPRSLRNSWTSEEEANPAVAKQEEVWPALGDRTLVPMVEQLFSHL
LKVINICAHVLDDVAPGPAIKAALPSLTNPPSLSPIRRKGKEKEPGEQASAPLSPKKGSE
ASPASRQSDASGPVTASKSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQNSAEKFGG
FLRSALDVLSQILELATLHDIGKCVEEILGYLKSCFSREPMMATVCVQQLLKTLFGTNLA
SQFDGLSSNPNKSQGRAQRLGSSSMRPGLYHYCFMAPYTHFTQALADASLRNMVQAEQDR
DASGWFDVLQKVSTQLKTGLTGATKNRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQ
RQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLS
YERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGANKADAGKELE
TQKEVVVSMLLRLIQYHQVLEMFILVLQQCHRESEDKWKRLSRQVADVILPMLAKQQMHI
DSHEALGVLNTLFEILAPSSLRPVDMLLRSMFVTPDTMAPVSTVQLWISGILAILRVLIS
QSTEDIVLSRIQELSFSPYLISCPIINRLREGDSTLTPEEHSEGTQMKSLPEETFSRFLL
QLVGILLEDIVTKQLRVEMSEQQHTFYCQELGTLLMCLIHIFKSGMFRRITAAASRLLTV
DSGDGSFYGLDGLNARVRAMVPTHPALVLLWCQILLLVSHTDHRWWAEVQQTPRRRSLSS
TKSLGPQLSGQEEDSDVAGKPGMCNREIVRRGALILFCDYVCQNLHDSEHLTWLIVNHIQ
DLINLSHEPPVQDFISAVHRNSAASGLFIQAIQSRCENLSTPTTLKKTLQCLEGIHLSQS
GAVLTLYVDKLLCTPFRVLARMVDTLACRRVEMLLAANLQSSMAQLPVEELTRIQEYLQS
SGLAQRHQRLYSLLDRLRLATAPGSRGPSPPVTSHPLDGDGPLALETIIPDKDWYLRLVK
SQCWTRSDSALLEGAELVNRIPPSDMSTFMMNSEFNLSLLAPCLGLGVREISGGQRSPLF
EAARLATLDRVTSLVQQLPATHHVFQPFLSVEPTAYWNKLNDLFGDAVFYRSLTTLARAL
AEYLLVFSKLPGHLHLPPEKERDTVKFVVMTLEALSWHLIHEQIPLSLDLQAGLDCCCLA
LQLPSLWSTLSTPEMVTRACSLIHCVRFILEAIVVRPGDQLLSPDRRTNTPKAARDDEVD
SNTQNPAYITAACEMVAEMVEALPSVLALGHKRNSDTPAFLTSVLRNIIISLARLPLVNS
YTRVPPLVWKLGWSPKPGGDFGTAFPEIPVEFLQEKEVFKEFIYRINTLGWTSRTQFEET
WATLLGVLVTQPLVMEQEESPPEEDTERTQINVLAVQAITSLVLSAMTVPVAGNPAVSCL
EQQPRNKPLKALDTRFGRKLSIIRGIVEQEIQAMVSKRENIATHHSYQAWDPVPSLSPAT
TGALISHDRLLLQINPERELGNMSYKLGQVSIHSVWLGNSITPLREEEWGEEEEEEADVP
TPASPPTSPLNSRKHRAGVDIHSCSQFLLELYSRWILPSGSARRTPIILISEVVRSLLVV
SDLFTERTQFEMMYLALAELRRVHPAEDEILIQYLVPATCKAAAVLGMDKAVAEPVTRLL
ESTLRSSHLPSKVGALHGALYVLECDLLDETAKQLVPVISDYVLSNLKGAAHCVNVHSQQ
HVLVMCATAFYLIENYPLDVGPEFSASIIQMCGVMLSGTEESTPSIIYHCILRGLERLLL
SEQLCRLEAESLVKLSVDRVNVHSPHRAMAALGLMLTCMYTGKEKISPGRTSDPSPATPD
SESVIVAMERVSVLFDRVRKGFPCEARVVARILPQFLDDFFPPQDVMNKVIGEFLSNQQP
YPQFMATVVYKVFQTLHSSGQSSMVRDWVMLSLSNFTQRSPVAMAVWSLSCFFVSASTSP
WVSAVLPHVVSRMGKLERVDVNLFCLVASDFYRHQIEEELDRRAFQSVFEVVAAPGNPYQ
RLLTCLRNVHKVASC
NT seq
9408 nt
NT seq
+upstream
nt +downstream
nt
atggcaaccctggaaaagctgatgaaggccttcgaatccctcaagtccttccagcagcag
cagcagcagcagcagcagcagccgccgccgccgccgccacctcagcctcctcagcctcct
cagccgctgccgcaggcgcagccgccgctccctcagcctcagccgccgcccccgccgccg
cccctgccgccccccggcccggccggggccgaggagccacttcaccgaccaaagaaagaa
ctctcagccaccaagaaagaccgcgtgaatcattgtctgacgatatgtgagaacatagtg
gcacagtcactcagaaattctccagagtttcagaaacttctgggcattgctatggaactc
tttctcctgtgcagtgatgatgcggagtcggatgtcaggatggtggccgacgagtgcctc
aacagagtcataaaagcgctgatggactcgaatcttccgaggttacagctggaactctac
aaggaaatcaaaaagaacggcgctccccggagcctgcgcgctgccctgtggaggttcgct
gagctggctcacctggttcggcctcagaaatgcaggccttacttggtaaaccttctgcct
tgcctgactcgaataagcaagagacctgaggaatctgttcaggagaccttggctgcagct
gtacctaaaattatggcttcttttggcaattttgcaaatgacaatgaaattaaggtccta
ttaaaggctttcatagcgaatctgaagtccagctcgcctaccgtccggcgcacagcagcc
ggctcagccgtgagcgtctgccagcactccaggagggcgcggtacttctacagctggctg
ctcagcgtgctcctgggtttgctggttcctgttgaggacgaacactctaccgtcctgatt
ctcggggtgctgctcacgttgaggtatttggtgcccttgctgcagcagcaggtcaaggac
acgagcctgaaaggcagctttggggtgacacggaaggaaatggaagtctctccctcgaca
gagcagctcctccaggtttatgaactgaccttgcattacactcagcaccaagaccacaac
gccgtgaccggggcactggagctcctgcagcagctcttcaggacgcccccgcccgagctt
ctgcaggccttgacctctccgggtggcgggcagctcagcggcgcgcagcccggacccggc
ggccggagccgcagcggcagcatcgcagagctcctagccggagggggttcttcatgcagc
cctgtcctttcaagaaaacaaaaagggaaagtgctcttcggagaggcagcagccttggag
gatgactccgagtccaggtcggagggcagcagccccgcctttacagcttcagtcaagggt
gagattggtggtgagctggcggcctcttccggggtctccactcctggctctgccggttca
gctgctgactccgtggggcacgacatcatcaccgagcagccccgctcacagcacacgctg
cagccggactcggtggatctgaccggctgtgacttggccagcgctgccaccgacggggat
gaggaggacatcctgagccacagctccagccagatcagtgccgtcccgtccgacccagcc
atggacctgaacgatggcacccaggcctcttccccagtcagtgacagttcccagaccacc
accgaagggcccgattcagctgtgaccccttcagacagttctgaaattgtgttagatggt
gccgacggccagtatccagggacgcaggtcggacagccgcaggacgaggatgaggaggct
gcgggcgccctcccggaggaagacgcagatgccttccgggactctgcagttgcccttcag
caagcacatttactgaaaagcatgggccacagccggcggccctccgatagcagtgtggac
acattcgtctcaagagatgaagctgccgaagcaggagaccaggagaacaagccttgccgg
atcaaaggtgacataggacagtctaccgatgacgattctgttcctcttgtccactgtgtc
cgcctgctctcggcttcctttttgctgactggagaaaaaaatgtgctggttccggacagg
gacgtgagggtcagcgtcaaggcgctggcactcagctgtgtgggagccgctgtggccctt
catcccgagtctttcttcagcaaactttacaaagtccctctcgaccccgcggagtaccct
gaggagcaatatgtgtccgacatcctgaactacatcgatcacggagacccccaggtcaga
ggggccacggccgttctctgcgggaccctcatctcctccatcctcagcaggtcccacttc
caggtgggagactggatgggcagcgttagagctcaaacaggaaatacattttctctggcg
gactgcattcctttgctgcggaaaactttgaaagatgagtcttctgttacttgcaagttg
gcctgcacagctgtgaggcactgtgtcatgagtctgtgcagcagtggctccagtgacctg
ggattgcagctcatcaccgatatgctgagcctcagggacagcgcctactggctggtgagg
acagagcttttggaaacgctcgcagagattgactttaggttggtgagctttctggaggca
aaagcagaaaacctgcacagaggggcccatcactacacagggcttttaaaactgcaagac
cgagtgctcaataatgtcgtcatctatttgcttggggacgaagaccccagggtgcgacat
gtcgccgcggctgcactgatgaggcttgtcccgaagctgttttataaatgtgaccaagga
caagctgacccagtagtggctgtggcaagagatcaaagcagcgtttacctgaaacttctc
atgcatgagactcagcctccgtctcacttctccgtcagcaccataaccagaatatacaga
ggctataacctactgccgagcatgacagatgtcactgtggaaaataacctctcgagagtc
atcgcggcagtttcccacgagctggtcacgtcgaccacgcgagcgctcacattcggatgc
tgcgaggctttgtgtcttctttccactgcctttccagtctgcgtttggagcttaggctgg
cattgtggggtgcccccgctgagcgcgtccgatgagtctcggaagagctgcactgtcggc
atggccacggtggtcctgaccttgctgtcgtccgcgtggttcccgcttgacctctctgcg
caccaggacgctctggtgctggctggaaacttgctcgcagccagcgcccccaggtctctg
agaaattcgtggacctctgaggaggaagccaacccagctgtcgccaagcaggaggaggtc
tggccggctctgggtgaccggaccctggtgcccatggtggagcagctcttctcccacctg
ctgaaggtgatcaatatctgcgcacacgtgctggacgatgtggctcctggaccggcaata
aaggcagccttgccgtccctcacaaaccctccctctctaagtccgatccgccggaagggg
aaggagaaagagccaggagagcaggcctctgcgcccttgagccccaagaagggcagtgaa
gccagtccagcctctcgacagtccgatgcctcggggcctgttactgcaagcaagtcctcg
tcactggggagcttctaccaccttccgtcatacctcaaattgcacgatgtcctgaaagct
actcacgctaactataaggttaccttggaccttcagaacagcgctgagaagtttgggggc
tttctgcgctccgccttggatgttctctcgcagatcctcgagctggcaacgctgcacgat
atcgggaagtgtgtcgaggagatcctcgggtacctgaagtcctgcttcagccgggagccc
atgatggccactgtttgcgttcagcagttgttgaagactctctttgggacaaacttggcc
tcccagttcgatggcttatcttccaaccccaacaagtcgcaaggccgagcgcagcgtctg
ggctcctccagcatgaggccaggcttataccactactgcttcatggctccctacacccac
ttcacccaggccttagccgacgccagcctgaggaacatggtgcaggccgagcaggaccgc
gatgcttcagggtggtttgacgtgcttcagaaagtgtccacccagctgaagaccggcctc
acgggcgccactaagaaccgtgcagataagaacgctattcacaatcacattcgtttgttc
gagcccctcgttataaaagccttaaagcagtacacaaccacaacgtccgtgcagctgcag
aggcaggtcttagatttgctggcacagctggttcagctgcgggtcaattactgtcttctg
gattcagatcaggtgtttattggatttgtgctgaagcagttcgaatacattgaagtaggc
cagttcagggaatcagaggcaattattccaaacatctttttcttcctggtattattgtct
tacgagcgctatcattcaaaacagatcattggaatccctaaaatcattcagctctgtgac
ggcatcatggccagcgggaggaaggctgtgacacatgccataccggctctgcagccgata
gtccatgacctgtttgtactgagaggggccaataaagctgacgcaggaaaagagcttgaa
acccagaaagaggtggtggtgtccatgctgctgagactcatccagtaccatcaggtgctg
gagatgttcatcctggtgctgcagcagtgtcacagggagagcgaggacaagtggaagcgg
ctgtcccggcaggtcgccgacgtcatcctcccgatgctggccaagcagcagatgcacatc
gattctcatgaagcccttggtgtcctgaatactttatttgagattctggccccttcttcc
ctccgtcccgtggacatgcttttacggagtatgtttgtcactccagacacaatggcaccc
gtgagcactgttcagctgtggatatcaggaatcctggccattttgagggttctcatctcc
cagtccactgaggacattgttctttctcgtatccaggagctctccttctctccgtattta
atctcctgtccaataattaataggctaagagagggggacagtactttgacaccggaagaa
cacagtgaagggacacaaatgaagagcctgccggaagaaacattctcaagatttctgcta
caactggttggcattcttttggaggatattgttacaaagcagctcagagtggaaatgagt
gaacagcaacatacgttctattgccaagaactgggcacgctgctcatgtgtctcatccac
atcttcaagtcggggatgttccggaggatcacagcagccgcctccaggctcctcacggtg
gacagcggcgacggcagtttctacggcctggacgggctgaacgcgcgggtgcgcgccatg
gtgcccacgcacccggcccttgtgctgctctggtgccagatcctgctgcttgtcagccac
accgaccaccgctggtgggcagaggtgcagcagacccccaggagacgtagtctgtccagt
acgaagtcactcggcccccagctgtccggacaggaggaggactccgacgtggccggcaaa
cccggcatgtgcaaccgagaaatagtgcggcggggagcgctcattctcttctgcgattat
gtctgtcagaacctgcacgattcagagcacttaacgtggctcatcgtgaatcatattcag
gacctgatcaatctgtcacatgagcccccggtgcaggattttattagcgctgttcatcgg
aactccgccgccagtggcctcttcatccaggcaattcagtctcgttgtgagaacctttca
acccccaccaccctgaagaagacgcttcagtgcttggaagggatccacctcagccagtcg
ggcgccgtgctaacgctgtacgtggacaagcttctgtgcaccccgttccgggtgctggct
cgcatggtcgacaccctggcctgtcgccgggtggagatgcttttggccgcaaatttacag
agcagcatggcccagttgccggtggaggaactaaccagaatccaggaataccttcagagc
agcgggctggctcagagacaccagaggctgtactccctgctggacaggcttcgccttgcc
accgcgccgggctctcgtggcccttctcctccagtcacatcccacccgctggacggggac
gggcccctggcactggagacaatcattccagacaaagactggtacctacgtctagtcaaa
tcccagtgctggaccaggtcagattctgcgctgctggaaggggcagaactggtgaatcgg
attcctcccagtgacatgagcacattcatgatgaactcggaattcaacttaagcctgctg
gcgccgtgcctgggcctgggtgtgcgcgaaatctccggaggccagaggagtccccttttc
gaagcggctcgcctggcgaccttggaccgtgtgaccagcctggttcagcagctccctgcc
acccaccatgtcttccagccgttcctctctgtggagcccaccgcctactggaacaaattg
aacgatctatttggggatgctgtgttttatcggtccttgaccactctggcccgggctctg
gccgagtacctgctggtattctccaaactgcccggccacttgcaccttcctcctgagaag
gagagggacacggtaaagtttgtggtcatgaccctcgaggccctgtcatggcatttgatc
catgagcagatcccgctgagtctggaccttcaggcgggcctggactgctgttgcctggcc
ctgcagctgcccagcctctggagcaccctatccaccccagagatggtgacccgcgcctgc
tctctaatccactgtgtccgcttcatcctggaagccattgtggtgcggcctggggaccag
cttctgagtccagacagaaggacgaacaccccaaaggctgccagagacgacgaagtcgat
tcaaacacacagaacccggcttatatcaccgcagcctgtgagatggtggcagagatggtg
gaggctttgccgtccgtgctggccttgggccataaaaggaacagcgacaccccagcgttt
ctcacctcagtgctcaggaacatcatcatcagcctggctcgccttcccctcgtcaacagc
tacacgcgcgtcccccctctggtttggaaacttggatggtcacccaaaccaggaggggat
tttggcacagcgttccctgagatcccggtggagttcctccaggagaaagaggtgtttaaa
gagttcatctatcgcatcaacacactagggtggaccagccgcacccagtttgaggaaaca
tgggccaccctcctcggtgtcctggtgactcagcccctggtgatggagcaggaggagagc
cctccggaggaagacacggagaggacccagatcaacgtcctggccgtgcaggccatcacc
tccctggtgctgagtgccatgaccgtgcccgtggccggcaacccagccgtcagctgcctg
gagcagcagccccggaacaagcccctgaaagctcttgacaccaggtttgggaggaagctg
agcatcatcagaggaatcgtggagcaggaaatccaagcgatggtttccaagagagagaat
atcgccacccatcactcgtaccaagcgtgggaccccgtcccttctctctccccagctact
acaggtgccctcatcagccatgaccggcttctgctgcagatcaaccccgagcgggagctg
ggcaacatgagctacaagctcggccaggtgtccattcactccgtgtggctggggaacagc
atcacgcccctgagagaggaagagtggggggaggaggaggaggaggaggccgacgtcccc
acacctgcgtcaccacccacgtcgccgctcaactccaggaagcaccgggccggagtcgac
atccactcctgctcccagtttctgctcgaattgtacagccgctggatcctgccgtcgggc
tcagccaggaggacccccatcatcctgatcagcgaagtggtccgatctctcctggtggtc
tcggacttgttcactgagcgcacccagtttgagatgatgtatctggcgctggcagagctg
cggagggtgcaccctgcagaagacgagattctcattcagtacctggtgcctgccacctgc
aaggcggctgccgtcctcggaatggacaaggcggtggctgagcccgtcacccggctgctg
gagagcaccctgaggagtagccacctgcccagcaaggtcggggccctgcatggcgccctc
tacgtgctggagtgtgacctcctggatgagacagcgaagcagctcgtcccagtcatcagt
gactacgtcctgtccaacctcaaaggggcggcccactgcgtgaacgttcacagccaacag
cacgtgctggtgatgtgtgccaccgccttctacctgattgagaactacccgctggacgtg
ggcccagaattctccgcatccataatacagatgtgtggggtgatgctgtccgggactgag
gagtccaccccgtccatcatttaccactgcatcctgcggggcctggagcgccttctgctc
tccgagcagctgtgccggctggaggccgaatccctggtcaagctgagtgtggacagagtg
aatgtgcacagcccacaccgggccatggcggccctgggcctgatgctcacctgcatgtac
acaggaaaggagaagatcagtccaggccgaacctcagaccccagccccgccaccccagac
agcgagtcagtgatcgtggccatggagcgggtgtccgttctttttgaccgggtcaggaaa
ggattcccctgtgaagccagagtggtggcacggatccttcctcagtttttagatgacttc
ttcccaccccaggacgtcatgaacaaagtcattggggaatttctgtccaaccagcagcca
tacccacagttcatggccaccgttgtgtacaaggttttccagactctgcacagcagcggg
cagtcgtccatggtccgggactgggtcatgctgtccctctccaacttcacacagaggagc
ccggtggccatggccgtgtggagcctctcctgcttctttgtcagcgcttccaccagcccc
tgggtgtctgccgtccttccccacgtcgtcagcaggatgggcaagctggagcgagtagac
gtgaacctcttctgcctggtggcctcagacttttacagacaccagatagaggaggagctg
gatcgccgggccttccagtctgtgttcgaggtggtcgcagctccgggaaacccataccag
cgactgttgacttgtttgcggaacgtccacaaggtcgcctcgtgctga
DBGET
integrated database retrieval system
