Hyaena hyaena (striped hyena): 120235617
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Entry
120235617 CDS
T07257
Symbol
SDHA
Name
(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00020
Citrate cycle (TCA cycle)
hhv00190
Oxidative phosphorylation
hhv01100
Metabolic pathways
hhv01200
Carbon metabolism
hhv04714
Thermogenesis
hhv04932
Non-alcoholic fatty liver disease
hhv05010
Alzheimer disease
hhv05012
Parkinson disease
hhv05014
Amyotrophic lateral sclerosis
hhv05016
Huntington disease
hhv05020
Prion disease
hhv05022
Pathways of neurodegeneration - multiple diseases
hhv05208
Chemical carcinogenesis - reactive oxygen species
hhv05415
Diabetic cardiomyopathy
Module
hhv_M00009
Citrate cycle (TCA cycle, Krebs cycle)
hhv_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
hhv_M00148
Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
120235617 (SDHA)
09102 Energy metabolism
00190 Oxidative phosphorylation
120235617 (SDHA)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
120235617 (SDHA)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
120235617 (SDHA)
09164 Neurodegenerative disease
05010 Alzheimer disease
120235617 (SDHA)
05012 Parkinson disease
120235617 (SDHA)
05014 Amyotrophic lateral sclerosis
120235617 (SDHA)
05016 Huntington disease
120235617 (SDHA)
05020 Prion disease
120235617 (SDHA)
05022 Pathways of neurodegeneration - multiple diseases
120235617 (SDHA)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
120235617 (SDHA)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
120235617 (SDHA)
Enzymes [BR:
hhv01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
120235617 (SDHA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Thi4
Pyr_redox_2
GIDA
DAO
FAD_binding_3
HI0933_like
Motif
Other DBs
NCBI-GeneID:
120235617
NCBI-ProteinID:
XP_039093944
LinkDB
All DBs
Position
Unknown
AA seq
665 aa
AA seq
DB search
MSRVRVVSRLLGARRLALTRAQWPATWQTGTCGFHFTIDGNKRSSAKVSDSISTQYPVVD
HEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNW
RWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLK
FGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCI
EDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTG
IYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGP
EKDHVYLQLHHLPPEQLAIRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKG
QVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGD
KVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLNMQKSMQNHAAVFRVGSVLQEGCEKI
SQLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKE
RIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVKTGKVSLEYRPVIDRTLNEADCATVPP
AIRSY
NT seq
1998 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggtcagggtggtgtcgcggctgttgggcgcccggcgcctggcactgactagg
gcgcagtggccagcgacatggcagacaggcacctgcggttttcacttcaccattgatggg
aataagaggtcttcagctaaagtttcagattcaatttccactcaatacccagtagtggac
catgaatttgatgcggtggtagtaggagctggaggggcaggcttgcgagctgcatttggc
ctttccgaggctgggtttaacacagcctgcgtcacaaagctctttcctaccagatcacac
accgttgcagcccagggagggatcaatgctgctctgggcaacatggaggaggacaactgg
aggtggcacttctacgacaccgtgaagggctccgactggctgggggaccaggatgccatc
cactacatgaccgagcaggcccctgcttccgtagtagagctcgagaattatggcatgccg
tttagcagaactgaagatgggaggatctaccagcgtgcttttggcggacagagcctcaag
tttgggaagggcgggcaggcccatcggtgttgctgtgtggctgaccgcactggccactcg
ctgctacacacgttgtatggaaggtctctgcgatatgataccagctattttgtagagtat
tttgccttggatcttctgatggaaaatggggaatgtcgtggtgttattgcactatgcata
gaagacgggtccatccatcgcatcagagcaaagaacactgttgtagctactggaggctac
gggcgtacctacttcagctgcacatctgcccacaccagcaccggtgacggcactgccatg
gtcaccagggcaggcctcccctgccaggacttggagtttgttcagtttcaccccacaggt
atatatggtgctggttgtctcattacggaagggtgccgtggagagggaggcattctcatt
aacagtcaaggtgaaaggtttatggaacgatatgccccggttgcaaaggacctggcgtcc
agagacgtcgtgtctcggtccatgactctggagatccgtgaaggaagaggctgtggccct
gagaaagatcatgtctacctgcagttgcaccacctgcctccagagcagttggccatacgg
ctgcctggcatttcagagacagccatgatctttgcaggcgtggatgtcaccaaggagccc
atccctgtccttcctaccgtgcattataacatgggcggcattcccaccaattacaagggg
caggttctgaggcatgtgaatggccaggatcaaatcgtgcctggcctgtatgcctgtggg
gaggctgcctgcgcctccgtgcacggtgccaaccgtcttggggcaaactcactcttggat
ctggttgtctttggccgggcatgtgccctgagtattgcagagtcctgcagacccggagat
aaagttcccccaattaaaccaaatgctggagaagagtctgtcatgaatcttgacaaattg
agatttgctgatggaagcataagaacatcagaactacgactcaacatgcagaagtccatg
caaaatcatgctgcagtgttccgtgtgggaagtgtgttacaggaaggttgcgagaaaatc
agccagctctatggagacctaaaacatctgaagacatttgaccgaggaatggtctggaac
accgacctggtggagaccctagagctgcagaacctgatgctctgtgcacttcagaccatt
tatggagcagaggctcggaaggagtcgcgtggtgctcacgccagggaagattacaaggag
cggattgacgagtatgattactccaagcccatccaggggcagcagaagaagccgtttgag
gagcactggaggaagcacaccctttcttatgttgatgtcaagactgggaaggtctccttg
gagtacagacccgtcattgacagaactttgaatgaggcagactgtgccacagtccctcca
gcgattcgctcctactga
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