Haemophilus influenzae KR494 (serotype f): HifGL_000613
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Entry
HifGL_000613 CDS
T02839
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
hik
Haemophilus influenzae KR494 (serotype f)
Pathway
hik00290
Valine, leucine and isoleucine biosynthesis
hik00620
Pyruvate metabolism
hik01100
Metabolic pathways
hik01110
Biosynthesis of secondary metabolites
hik01210
2-Oxocarboxylic acid metabolism
hik01230
Biosynthesis of amino acids
Module
hik_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hik00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
HifGL_000613 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HifGL_000613 (leuA)
Enzymes [BR:
hik01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
HifGL_000613 (leuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
NAD_binding_10
RdfA
Motif
Other DBs
NCBI-ProteinID:
AGV11444
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Position
614952..616499
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AA seq
515 aa
AA seq
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MTDRVIIFDTTLRDGEQALKASLTVKEKLQIALALERLGVDVMEVGFPVSSQGDFESVQT
IARHIKNARVAALSRAVDKDIDAAYQALKVAEAFRIHTFIASSALHVEAKLKRSFDDVVG
MAVAAVKRARNYTDDVEFSCEDAGRTGIDNICRIVEAAINAGATTVNIPDTVGFCLPNEY
GNIIAQVHNRVPNIDKAVISVHCHNDLGMATANSLTAVQNGARQIECTINGIGERAGNTS
LEEVVMAMKVRQDFMDVDTRINTQEIHRVSQMVSQLCNMPIQPNKAIVGSNAFAHSSGIH
QDGMLKNKNTYEIMSPETIGLKKEKLNLTARSGRAAVKGHMADMGYNEQDYDLDKLYDAF
LKLADKKGQVFDYDLEALAFIDMQQGDEDRLVLDKLSAHSTKEYPATAFVQLKLDGEKLS
TSSIGGNGPVDAVYNAILNLTGLEIKMSHYNLTAKGEGAEALGQVDIVVEHEGRKFHGVG
LATDIVESSALALVHAINAIYRTHKVADIKNHKQH
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgacagatcgcgttattatttttgatacgactttgcgtgatggggaacaggcgttaaaa
gcaagtttgacggtaaaagaaaaattacagatcgctttagcacttgaacgcttaggcgtg
gatgtaatggaagtggggttccccgtttcttctcaaggagattttgaatctgttcaaacc
attgcgcgccatatcaaaaacgctcgtgttgccgcgttatctcgagccgtagataaagac
attgatgccgcataccaagcattgaaagtcgctgaagcatttcgtattcatacttttatt
gcaagctcggcattacacgttgaagcgaaattaaaacgttcttttgatgatgtagtagga
atggcagttgcagcagtgaaacgcgcacgtaattatacggatgatgttgagttttcttgc
gaagatgcggggcgtacaggcattgacaatatctgtcgtattgttgaagccgcaatcaat
gcaggcgcaactacagtaaatattcccgatacagtcggtttctgcttaccaaatgaatat
ggcaacattattgctcaagtgcataatcgcgtgccgaatatcgacaaagctgtgatttct
gtgcattgccacaatgacttaggtatggcaacggctaattctttaacggcagtgcaaaat
ggtgcgcgtcaaattgaatgtactattaatggaattggggaacgtgcgggcaatacttcc
cttgaggaagtcgtgatggcaatgaaagtgcgtcaggattttatggatgtggatactcgt
attaatacccaagaaattcatcgcgtgagtcaaatggttagccagctttgcaatatgcca
attcaaccgaataaagccattgtaggctcaaatgcttttgcccattcttctggtattcat
caagatggtatgttgaaaaacaaaaatacctacgaaattatgtctccagaaaccattggt
ttgaaaaaagaaaaattgaatttaaccgcacgttctgggcgtgcggctgtgaaaggtcat
atggcggatatgggctacaacgaacaagattatgatttggataaattgtatgacgcgttc
ttaaaattggcggataaaaaaggtcaagtgttcgattatgacttggaagccttggcattt
atcgatatgcaacaaggggatgaagatcgtttggtattagataaactttctgcgcattca
accaaagaatatccagcaacagcctttgttcaattgaaattagatggcgaaaaattaagt
acgtcttcaattggcggaaatggcccagtagatgcggtttataacgccatcttaaattta
acgggtttagaaattaaaatgtctcactataacttaaccgccaaaggcgagggtgcagaa
gcattagggcaagtggatattgtggtggaacacgaagggcgtaaattccacggtgttggt
ttagcaacagatattgttgaatcttccgcacttgctttagtccacgctatcaatgccatt
tatcgcacgcataaagtggcagatattaagaatcataaacagcattaa
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