Hylobates moloch (silvery gibbon): 116458587
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Entry
116458587 CDS
T08803
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh00760
Nicotinate and nicotinamide metabolism
hmh01100
Metabolic pathways
hmh04068
FoxO signaling pathway
hmh04148
Efferocytosis
hmh04152
AMPK signaling pathway
hmh04211
Longevity regulating pathway
hmh04213
Longevity regulating pathway - multiple species
hmh04218
Cellular senescence
hmh04310
Wnt signaling pathway
hmh04922
Glucagon signaling pathway
hmh04936
Alcoholic liver disease
hmh05031
Amphetamine addiction
hmh05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
116458587 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
116458587 (SIRT1)
04068 FoxO signaling pathway
116458587 (SIRT1)
04152 AMPK signaling pathway
116458587 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
116458587 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
116458587 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
116458587 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
116458587 (SIRT1)
04213 Longevity regulating pathway - multiple species
116458587 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
116458587 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
116458587 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
116458587 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hmh03036
]
116458587 (SIRT1)
03029 Mitochondrial biogenesis [BR:
hmh03029
]
116458587 (SIRT1)
Enzymes [BR:
hmh01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
116458587 (SIRT1)
Chromosome and associated proteins [BR:
hmh03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
116458587 (SIRT1)
Mitochondrial biogenesis [BR:
hmh03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
116458587 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
116458587
NCBI-ProteinID:
XP_031994251
EnsemblRapid:
ENSHMOG00005002106
LinkDB
All DBs
Position
Unknown
AA seq
747 aa
AA seq
DB search
MADEAALALQPSGSPSAAGAEREAASSPAGEPLRKRPRRDGPGLERSPGEPGGAAPEREV
PAAAGGCPAAAAALWREAEAEAAAAAGGEQEAQATAAAGEGDNGPGLQGPSREPPLADNF
YDEDDDDEGEEEEEAAAAAIGYRDNLLFGDEIITNGFHSCESDEEDRASHASSSDWTPRP
RIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDI
NTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIE
YFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRII
QCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPE
QFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLG
DCDVIINELCHRLGGEYAKLCCNPIKLSEITEKPPRTQKELAYLSELPPTPLHISEDSSS
PERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDL
KNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSD
SEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDIPERAGGAGFGTD
GDDQEAINEAISIKQEVTDMNCPSNKS
NT seq
2244 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcagccctcgcccttcagcccagcggctccccctcggcggcgggggcc
gagagggaggccgcgtcgtcccccgccggggagccgctccgcaagaggccgcggagagat
ggtcctggcctcgagcggagcccgggcgagcccggtggggcggccccagagcgtgaggtg
ccggcggcggccggcggctgcccggctgcggcggcggcgctgtggcgggaggcggaggca
gaggcggcggcggcggcgggcggggagcaagaggcccaggcgactgcggcggctggggaa
ggagacaatgggccgggcctgcagggcccatctcgggagccaccgctggccgacaacttc
tacgacgaagacgacgacgacgagggcgaggaggaggaagaggcggcggcggcggcgatt
gggtaccgagataaccttctgtttggtgatgaaattatcactaatggttttcattcctgt
gaaagtgatgaggaggatagagcctcacatgcaagctctagtgattggactccaaggcca
cggataggtccatatacttttgttcagcaacatcttatgattggcacagatcctcgaaca
attcttaaagatttattgccggaaacaattcctccacctgagttggatgatatgacactg
tggcagattgttattaatatcctttcagaaccaccaaaaaggaaaaaaagaaaagatatt
aatacaattgaagatgctgtgaaattactgcaagagtgcaaaaaaattatagttctaact
ggagctggggtgtctgtttcatgtggaatacctgacttcaggtcaagggatggtatttat
gctcgccttgctgtagacttcccagatcttccagatcctcaagcgatgtttgatattgaa
tatttcagaaaagatccaagaccattcttcaagtttgcaaaggaaatatatcctggacaa
ttccaaccatctctctgtcacaaattcatagctttgtcagataaggaaggaaaactactt
cgcaactatacccagaacatagacacgctggaacaggttgcgggaatccaaaggataatt
cagtgtcatggttcctttgcaacagcatcttgcctgatttgtaaatacaaagttgactgt
gaagctgtacgaggagatatttttaatcaggtagttcctcgatgtcctaggtgcccagct
gatgaaccgcttgctatcatgaaaccagagattgtgttttttggtgaaaatttaccagaa
cagtttcatagagccatgaagtatgacaaagatgaagttgaccttctcattgttattggg
tcttccctcaaagtaagaccagtagctctaattccaagttccataccccatgaagtgcct
cagatattaattaatagagaacctttgcctcatctgcattttgatgtagagcttcttgga
gactgtgatgtcataattaatgaattgtgtcataggttaggtggtgaatatgccaaactt
tgctgtaaccctataaagctctcagaaattactgaaaaacctccacgaacacaaaaagaa
ttggcttatttgtcagagttgccacccacacctcttcatatttcagaagactcaagttca
ccagaaagaacttcaccaccagattcttcagtgattgtcacacttttagaccaagcagct
aagagtaatgatgatttagatgtgtctgaatcaaaaggttgtatggaagaaaaaccacag
gaagtacaaacttctaggaatgttgaaagtattgctgaacagatggaaaatccggatttg
aagaatgttggttccagtactggggagaaaaatgaaagaacttcagtggctggaacagtg
agaaaatgctggcctaatagagtggcaaaggagcagattagtaagcggcttgatggtaat
cagtatctgtttttgccaccaaatcgttacattttccatggcgctgaggtatattcagac
tctgaagacgacgtcttatcctctagttcttgtggcagtaacagtgatagtgggacatgc
cagagtccaagtttagaagaacccatggaggatgaaagtgaaattgaagaattctacaat
ggcttagaagatgagcctgatattccagagagagctggaggagctggatttgggactgat
ggagatgatcaagaggcaattaatgaagctatatctataaaacaggaagtaacagacatg
aactgtccatcaaacaaatcatag
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integrated database retrieval system
