Homo sapiens (human): 10595
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Entry
10595 CDS
T01001
Symbol
ERN2, IRE1-BETA, IRE1b, IRE2p, hIRE2p
Name
(RefSeq) endoplasmic reticulum to nucleus signaling 2
KO
K11715
serine/threonine-protein kinase/endoribonuclease IRE2 [EC:
2.7.11.1
3.1.26.-]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
10595 (ERN2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
10595 (ERN2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: Other
IRE family
10595 (ERN2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Ribonuc_2-5A
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Pkinase_fungal
ABC1
PQQ
Kdo
Motif
Other DBs
NCBI-GeneID:
10595
NCBI-ProteinID:
NP_150296
OMIM:
604034
HGNC:
16942
Ensembl:
ENSG00000134398
UniProt:
Q76MJ5
A5YM46
A5YM65
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All DBs
Position
16:complement(23690310..23713222)
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AA seq
926 aa
AA seq
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MASAVRGSRPWPRLGLQLQFAALLLGTLSPQVHTLRPENLLLVSTLDGSLHALSKQTGDL
KWTLRDDPVIEGPMYVTEMAFLSDPADGSLYILGTQKQQGLMKLPFTIPELVHASPCRSS
DGVFYTGRKQDAWFVVDPESGETQMTLTTEGPSTPRLYIGRTQYTVTMHDPRAPALRWNT
TYRRYSAPPMDGSPGKYMSHLASCGMGLLLTVDPGSGTVLWTQDLGVPVMGVYTWHQDGL
RQLPHLTLARDTLHFLALRWGHIRLPASGPRDTATLFSTLDTQLLMTLYVGKDETGFYVS
KALVHTGVALVPRGLTLAPADGPTTDEVTLQVSGEREGSPSTAVRYPSGSVALPSQWLLI
GHHELPPVLHTTMLRVHPTLGSGTAETRPPENTQAPAFFLELLSLSREKLWDSELHPEEK
TPDSYLGLGPQDLLAASLTAVLLGGWILFVMRQQQPQVVEKQQETPLAPADFAHISQDAQ
SLHSGASRRSQKRLQSPSKQAQPLDDPEAEQLTVVGKISFNPKDVLGRGAGGTFVFRGQF
EGRAVAVKRLLRECFGLVRREVQLLQESDRHPNVLRYFCTERGPQFHYIALELCRASLQE
YVENPDLDRGGLEPEVVLQQLMSGLAHLHSLHIVHRDLKPGNILITGPDSQGLGRVVLSD
FGLCKKLPAGRCSFSLHSGIPGTEGWMAPELLQLLPPDSPTSAVDIFSAGCVFYYVLSGG
SHPFGDSLYRQANILTGAPCLAHLEEEVHDKVVARDLVGAMLSPLPQPRPSAPQVLAHPF
FWSRAKQLQFFQDVSDWLEKESEQEPLVRALEAGGCAVVRDNWHEHISMPLQTDLRKFRS
YKGTSVRDLLRAVRNKKHHYRELPVEVRQALGQVPDGFVQYFTNRFPRLLLHTHRAMRSC
ASESLFLPYYPPDSEARRPCPGATGR
NT seq
2781 nt
NT seq
+upstream
nt +downstream
nt
atggcgagtgcggtcagggggtcgaggccgtggccccggctggggctccagctccagttc
gcggcgctgctgctcgggacgctgagtccacaggttcatactctcaggccagagaacctc
ctgctggtgtccaccttggatggaagtctccacgcactaagcaagcagacaggggacctg
aagtggactctgagggatgatcccgtcatcgaaggaccaatgtacgtcacagaaatggcc
tttctctctgacccagcagatggcagcctgtacatcttggggacccaaaaacaacaggga
ttaatgaaactgccattcaccatccctgagctggttcatgcctctccctgccgcagctct
gatggggtcttctacacaggccggaagcaggatgcctggtttgtggtggaccctgagtca
ggggagacccagatgacactgaccacagagggtccctccaccccccgcctctacattggc
cgaacacagtatacggtcaccatgcatgacccaagagccccagccctgcgctggaacacc
acctaccgccgctactcagcgccccccatggatggctcacctgggaaatacatgagccac
ctggcgtcctgcgggatgggcctgctgctcactgtggacccaggaagcgggacggtgctg
tggacacaggacctgggcgtgcctgtgatgggcgtctacacctggcaccaggacggcctg
cgccagctgccgcatctcacgctggctcgagacactctgcatttcctcgccctccgctgg
ggccacatccgactgcctgcctcaggcccccgggacacagccaccctcttctctaccttg
gacacccagctgctaatgacgctgtatgtggggaaggatgaaactggcttctatgtctct
aaagcactggtccacacaggagtggccctggtgcctcgtggactgaccctggcccccgca
gatggccccaccacagatgaggtgacactccaagtctcaggagagcgagagggctcaccc
agcactgctgttagatacccctcaggcagtgtggccctcccaagccagtggctgctcatt
ggacaccacgagctacccccagtcctgcacaccaccatgctgagggtccatcccaccctg
gggagtggaactgcagagacaagacctccagagaatacccaggccccagccttcttcttg
gagctattgagcctgagccgagagaaactttgggactccgagctgcatccagaagaaaaa
actccagactcttacttggggctgggaccccaagacctgctggcagctagcctcactgct
gtcctcctgggagggtggattctctttgtgatgaggcagcaacagccgcaggtggtggag
aagcagcaggagacccccctggcacctgcagactttgctcacatctcccaggatgcccag
tccctgcactcgggggccagccggaggagccagaagaggcttcagagtccctcaaagcaa
gcccagccactcgacgaccctgaagctgagcaactcaccgtagtggggaagatttccttc
aatcccaaggacgtgctgggccgcggggcaggcgggactttcgttttccggggacagttt
gagggacgggcagtggctgtcaagcggctcctccgcgagtgctttggcctggttcggcgg
gaagttcaactgctgcaggagtctgacaggcaccccaacgtgctccgctacttctgcacc
gagcggggaccccagttccactacattgccctggagctctgccgggcctccttgcaggag
tacgtagaaaacccggacctggatcgcgggggtctggagcccgaggtcgtgctgcagcag
ctgatgtctggcctggcccacctgcactctttacacatagtgcaccgggacctgaagcca
ggaaatattctcatcaccgggcctgacagccagggcctgggcagagtggtgctctcagac
ttcggcctctgcaagaagctgcctgctggccgctgtagcttcagcctccactccggcatc
cccggcacggaaggctggatggcgcccgagcttctgcagctcctgccaccagacagtcct
accagcgctgtggacatcttctctgcaggctgcgtgttctactacgtgctttctggtggc
agccacccctttggagacagtctttatcgccaggcaaacatcctcacaggggctccctgt
ctggctcacctggaggaagaggtccacgacaaggtggttgcccgggacctggttggagcc
atgttgagcccactgccgcagccacgcccctctgccccccaggtgctggcccaccccttc
ttttggagcagagccaagcaactccagttcttccaggacgtcagtgactggctggagaag
gagtccgagcaggagcccctggtgagggcactggaggcgggaggctgcgcagtggtccgg
gacaactggcacgagcacatctccatgccgctgcagacagatctgagaaagttccggtcc
tataaggggacatcagtgcgagacctgctccgtgctgtgaggaacaagaagcaccactac
agggagctcccagttgaggtgcgacaggcactcggccaagtccctgatggcttcgtccag
tacttcacaaaccgcttcccacggctgctcctccacacgcaccgagccatgaggagctgc
gcctctgagagcctcttcctgccctactacccgccagactcagaggccaggaggccatgc
cctggggccacagggaggtga
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